View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List K48-linked Tetra-Ubiquitin Recombinant Protein Catalog # MBS845352 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name K48-linked Tetra-Ubiquitin, Recombinant Protein Full Product Name K48-linked Tetra-Ubiquitin Product Synonym Names K48-linked Tetra-Ubiquitin Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Purity/Purification >=95% Form/Format 2.5 mg/ml in 20 mM Tris-HCl, pH 7.5, 0.15 M NaCl and 1 mM EDTA.Appearance: Liquid Concentration 2.5 mg/ml (lot specific) Handling Centrifuge the vial prior to opening. Preparation and Storage At -80 degree CShelf Life: 12 months Other Notes Small volumes of K48-linked Tetra-Ubiquitin recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for K48-linked Tetra-Ubiquitin recombinant protein Background: Poly-ubiquitylation of target proteins through linkage at K48, is now the most thoroughly studied of the various chain linkages, and was once considered the hallmark of this post-translational modification. It is now clear that many, if not all, poly-Ub chain topologies likely play distinct and important roles in regulating cellular processes. Nevertheless, K48 linkage remains a critical pathway for the cells to maintain homeostasis through proteolytic degradation, and as such remains very intriguing for the study of DUBs that play a role in the degradation, as well as the proteasome itself. These tetra-ubiquitin chains are generated from the enzymatic linkage (E2-25K) of wild-type ubiquitin through lysine 48. The most distal ubiquitin contains an arginine substitution for a lysine at position 48, limiting the chain length. Product Categories/Family for K48-linked Tetra-Ubiquitin recombinant protein Proteins and Enzymes; Proteins and Enzymes (A-Z) Diabetes; Obesity & Metabolic Syndrome; Signaling Pathways in Diabetes and Obesity; GSK-3/Wnt Signaling; Proteins/Enzymes Applications Tested/Suitable for K48-linked Tetra-Ubiquitin recombinant protein Western Blot (WB) Testing Data of K48-linked Tetra-Ubiquitin recombinant protein TOP Molecular Weight 34.233 kDa (Band migrates faster on gels)[Similar Products] TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP