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K48-linked Tri-Ubiquitin Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS844580
Testing Data
Unit / Price
0.05 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

K48-linked Tri-Ubiquitin, Recombinant Protein

 Also Known As   

K48-linked Tri-Ubiquitin

 Product Synonym Names    K48-linked Tri-Ubiquitin
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Purity/Purification    >=95%
 Form/Format    2.5 mg/ml in 20 mM Tris-HCl, pH 7.5, 0.15 M NaCl and 1 mM EDTA.
Appearance: Liquid
 Concentration    2.5 mg/ml (lot specific)
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 Handling    Centrifuge the vial prior to opening.
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 Preparation and Storage    At -80 degree C
Shelf Life: 12 months
 Other Notes    Small volumes of K48-linked Tri-Ubiquitin recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for K48-linked Tri-Ubiquitin recombinant protein

   Background: Poly-ubiquitylation of target proteins through linkage at K48, is now the most thoroughly studied of the various chain linkages, and was once considered the hallmark of this post-translational modification. It is now clear that many, if not all, poly-Ub chain topologies likely play distinct and important roles in regulating cellular processes. Nevertheless, K48 linkage remains a critical pathway for the cells to maintain homeostasis through proteolytic degradation, and as such remains very intriguing for the study of DUBs that play a role in the degradation, as well as the proteasome itself. These tri-ubiquitin chains are generated from the enzymatic linkage (E2-25K) of wild-type ubiquitin through lysine 48. The most distal ubiquitin contains an arginine substitution for a lysine at position 48, limiting the chain length.
 Product Categories/Family for K48-linked Tri-Ubiquitin recombinant protein    Proteins and Enzymes; Proteins and Enzymes (A-Z)Diabetes, Obesity & Metabolic Syndrome; Signaling Pathways in Diabetes and Obesity; GSK-3/Wnt Signaling; Proteins/Enzymes
 Applications Tested/Suitable for K48-linked Tri-Ubiquitin recombinant protein   

Western Blot (WB)

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 Testing Data of K48-linked Tri-Ubiquitin recombinant protein    K48-linked Tri-Ubiquitin recombinant protein Testing Data image
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 Molecular Weight    25.686 kDa (Band migrates faster on gels) [Similar Products]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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