NP_005801
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
17kDa (153aa)
NCBI Official Full Name
killer cell lectin-like receptor subfamily G member 1 isoform b
NCBI Official Synonym Full Names
killer cell lectin like receptor G1
NCBI Official Synonym Symbols
2F1; MAFA; MAFA-L; CLEC15A; MAFA-2F1; MAFA-LIKE [Similar Products]
NCBI Protein Information
killer cell lectin-like receptor subfamily G member 1
UniProt Protein Name
Killer cell lectin-like receptor subfamily G member 1
UniProt Synonym Protein Names
C-type lectin domain family 15 member A; ITIM-containing receptor MAFA-L; MAFA-like receptor; Mast cell function-associated antigen
UniProt Synonym Gene Names
NCBI Summary for KLRG1
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. [provided by RefSeq, Jun 2016]
UniProt Comments for KLRG1
Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
Product References and Citations for KLRG1 recombinant protein
Schwartzkopff S, Grundemann C, et al. (2007). J Immunol. 179 (2):1022-9.; Ibegbu CC, Xu YX, et al. (2005). J Immunol. 174 (10):6088-94.
Research Articles on KLRG1
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Products associated with KLRG1 recombinant protein
Pathways associated with KLRG1 recombinant protein
Diseases associated with KLRG1 recombinant protein
Organs/Tissues associated with KLRG1 recombinant protein
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