Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow KRT17  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • angiopoietin-like protein2 (ANGPTL2) ELISA Kit
 • Coagulation Factor VIII Related Antigen (F8-AG) ELISA Kit
 • Glutamate--cysteine ligase, chloroplastic (GSH1) Recombinant Protein
 • CK-18-KRT18 ELISA Kit
 • hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid d... ELISA Kit
 • interleukin 6 receptor (IL6R) ELISA Kit
 • GUCY2C Antibody
 • PKC theta (PRKCQ) Antibody
 • LIPC ELISA Kit
 • TNF-a Antibody
 • Ras and Rab interactor 3 (Rin3) Recombinant Protein
 • Vacuolar protein sorting-associated protein 33B (Vps33b) Recombinant Protein
 • Disintegrin and metalloproteinase domain-containing protein ... ELISA Kit
 • 14 kDa fusion protein (A30L) Recombinant Protein
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

KRT17 recombinant protein

Scan QR to view Datasheet Catalog #    MBS205760
SDS-Page
Unit / Price
0.1 mg  /  $375 +1 FREE 8GB USB
0.5 mg  /  $925 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

KRT17, Recombinant Protein

★Popular Item★
 Also Known As   

KRT17, 1-432aa, Human, His tag, E Coli (Denatured)

 Product Synonym Names    Keratin type I cytoskeletal 17; Keratin; type I cytoskeletal 17; K17; PC; PC2; PCHC1
 Product Gene Name   

KRT17 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence    MGSSHHHHHH SSGLVPRGSH MGSMTTSIRQ FTSSSSIKGS SGLGGGSSRT SCRLSGGLGA GSCRLGSAGG LGSTLGGSSY SSCYSFGSGG GYGSSFGGVD GLLAGGEKAT MQNLNDRLAS YLDKVRALEE ANTELEVKIR DWYQRQAPGP ARDYSQYYRT IEELQNKILT ATVDNANILL QIDNARLAAD DFRTKFETEQ ALRLSVEADI NGLRRVLDEL TLARADLEMQ IENLKEELAY LKKNHEEEMN ALRGQVGGEI NVEMDAAPGV DLSRILNEMR DQYEKMAEKN RKDAEDWFFS KTEELNREVA TNSELVQSGK SEISELRRTM QALEIELQSQ LSMKASLEGN LAETENRYCV QLSQIQGLIG SVEEQLAQLR CEMEQQNQEY KILLDVKTRL EQEIATYRRL LEGEDAHLTQ YKKEPVTTRQ VRTIVEEVQD GKVISSREQV HQTTR
 OMIM    Z19574 Genomic DNA
 3D Structure    ModBase 3D Structure for Q04695
Section Bar
 Host    E Coli
Section Bar
 Purity/Purification    > 90% by SDS-PAGE
 Form/Format    Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol 0.4M urea
 Concentration    0.5 mg/ml (determined by Bradford assay) (lot specific)
Section Bar
 Antigen Species    Human
 Tag Information    His-tag
Section Bar
 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of KRT17 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for KRT17 recombinant protein

   KRT17, as known as keratin17, is a type I cytokeratin. It is found in nail beds, hair follicles, sebaceous glands, and other epidermal appendages. Mutations in KRT17 lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. Recombinant human KRT17 protein, fused to His-tag at N-terminus, was expressed in E Coli.
 Product Categories/Family for KRT17 recombinant protein    Signal Transduction
 Applications Tested/Suitable for KRT17 recombinant protein   

SDS-PAGE

Section Bar
 SDS-Page of KRT17 recombinant protein    KRT17 recombinant protein SDS-Page image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for KRT17. It may not necessarily be applicable to this product.
 NCBI GI #    4557701
 NCBI GeneID    3872
 NCBI Accession #    NP_000413 [Other Products]
 NCBI GenBank Nucleotide #    NM_000422.2 [Other Products]
Section Bar
 UniProt Primary Accession #    Q04695 [Other Products]
 UniProt Secondary Accession #    Q6IP98; Q8N1P6; A5Z1M9; A5Z1N0; A5Z1N1; A5Z1N2; A6NDV6; A6NKQ2 [Other Products]
 UniProt Related Accession #    Q04695 [Other Products]
 Molecular Weight    50.5 kDa (455aa)
Table BarTOPTable Bar
 NCBI Official Full Name    keratin, type I cytoskeletal 17
 NCBI Official Synonym Full Names    keratin 17
 NCBI Official Symbol    KRT17 [Similar Products]
 NCBI Official Synonym Symbols   
PC; K17; PC2; 39.1; CK-17; PCHC1
[Similar Products]
 NCBI Protein Information    keratin, type I cytoskeletal 17
 UniProt Protein Name    Keratin, type I cytoskeletal 17
 UniProt Synonym Protein Names   
39.1; Cytokeratin-17; CK-17; Keratin-17; K17
 Protein Family    Keratin
 UniProt Gene Name    KRT17 [Similar Products]
 UniProt Synonym Gene Names    CK-17; K17 [Similar Products]
Section Bar
 NCBI Summary for KRT17    This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq, Aug 2008]
Section Bar
 UniProt Comments for KRT17    Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair (). Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (). Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors (). May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.
Table BarTOPTable Bar
 

Product References and Citations for KRT17 recombinant protein

   McLean WH. et al. (1995) Nat Genet. 9:273-278.; Troyanovsky SM. et al. (1993) Eur J Cell Biol. 59: 127-137.;
Section Bar
 Research Articles on KRT17    1. Krt17 was demonstrated to contribute to areca nut-induced oral malignancy
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with KRT17 recombinant proteinPathways associated with KRT17 recombinant protein
 Reference Product  PubMed Publications
 KRT16 recombinant protein  >35 publications with KRT17 and KRT16
 KRT6A recombinant protein  >29 publications with KRT17 and KRT6A
 KRT6B recombinant protein  >25 publications with KRT17 and KRT6B
 KRT5 recombinant protein  >11 publications with KRT17 and KRT5
 JUN recombinant protein  >9 publications with KRT17 and JUN
 KRT14 recombinant protein  >6 publications with KRT17 and KRT14
 TP53 recombinant protein  >1 publications with KRT17 and TP53
 EGFR recombinant protein  >1 publications with KRT17 and EGFR
 Products by Pathway  Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Glucocorticoid Receptor Regulatory Network Pathway antibodies  Glucocorticoid Receptor Regulatory Network Pathway Diagram
 Keratinization Pathway antibodies  Keratinization Pathway Diagram
Diseases associated with KRT17 recombinant proteinOrgans/Tissues associated with KRT17 recombinant protein
 Disease Name  Pubmed Publications
 Pachyonychia Congenita Antibodies  >35 publications with KRT17 and Pachyonychia Congenita
 Carcinoma, Squamous Cell Antibodies  >14 publications with KRT17 and Carcinoma, Squamous Cell
 Breast Neoplasms Antibodies  >8 publications with KRT17 and Breast Neoplasms
 Adenocarcinoma Antibodies  >8 publications with KRT17 and Adenocarcinoma
 Pain Antibodies  >7 publications with KRT17 and Pain
 Precancerous Conditions Antibodies  >4 publications with KRT17 and Precancerous Conditions
 Skin Neoplasms Antibodies  >4 publications with KRT17 and Skin Neoplasms
 Cell Transformation, Neoplastic Antibodies  >3 publications with KRT17 and Cell Transformation, Neoplastic
 Hyperplasia Antibodies  >3 publications with KRT17 and Hyperplasia
 Inflammation Antibodies  >3 publications with KRT17 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >30 publications with KRT17 and Skin
 Mouth Antibodies  >7 publications with KRT17 and Mouth
 Bladder Antibodies  >3 publications with KRT17 and Bladder
 Lymph Node Antibodies  >3 publications with KRT17 and Lymph Node
 Bone Antibodies  >3 publications with KRT17 and Bone
 Lymph Antibodies  >3 publications with KRT17 and Lymph
 Mammary Gland Antibodies  >2 publications with KRT17 and Mammary Gland
 Stomach Antibodies  >2 publications with KRT17 and Stomach
 Cervix Antibodies  >2 publications with KRT17 and Cervix
 Thyroid Antibodies  >1 publications with KRT17 and Thyroid
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions