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Klk14 recombinant protein :: Kallikrein-14 (Klk14) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS7092480
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Unit / Price
0.05 mg (E-Coli)  /  $625 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $845 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $930 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,305 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Kallikrein-14 (Klk14), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse Kallikrein-14 (Klk14)

 Product Synonym Names    Glandular kallikrein KLK14
 Product Gene Name   

Klk14 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Klk14 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    24-250aa; Full Length of Mature Protein
 Sequence    IIGGYRCVRN SQPWQVALQA GPGHRFLCGG VLLSDQWVIT AAHCARPILH VALGKHNIRR WEATQQVVRV ARQVPHPQYQ PQAHDNDLML LKLQKKVRLG RAVKTISVAS SCASPGTPCR VSGWGTIASP IARYPTALQC VNVNIMSEQA CHRAYPGIIT SGMVCAGVPE GGKDSCQGDS GGPLVCGGQL QGLVSWGMER CAMPGYPGVY ANLCNYHSWI QRTMQSN
 3D Structure    ModBase 3D Structure for Q8CGR5
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Klk14 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Klk14 recombinant protein

   Serine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity. May activate/inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1, KLK3, KLK5 and KLK11. May function in seminal clot liquefaction through direct cleavage of the semenogelin SEMG1 and SEMG2 and activation of KLK3. May function through desmoglein DSG1 cleavage in epidermal desquamation a process by which the most superficial corneocytes are shed from the skin surface. May be involved in several aspects of tumor progression including growth, invasion and angiogenesis
 Product Categories/Family for Klk14 recombinant protein    Tags & Cell Markers
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 SDS-Page of Klk14 recombinant protein    Klk14 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Klk14. It may not necessarily be applicable to this product.
 NCBI GI #    33469049
 NCBI GeneID    317653
 NCBI Accession #    NP_777355.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_174866.3 [Other Products]
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 UniProt Primary Accession #    Q8CGR5 [Other Products]
 UniProt Related Accession #    Q8CGR5 [Other Products]
 Molecular Weight    40.5kDa [Similar Products]
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 NCBI Official Full Name    kallikrein-14 preproprotein
 NCBI Official Synonym Full Names    kallikrein related-peptidase 14
 NCBI Official Symbol    Klk14 [Similar Products]
 NCBI Official Synonym Symbols   
GK14
[Similar Products]
 NCBI Protein Information    kallikrein-14
 UniProt Protein Name    Kallikrein-14
 UniProt Synonym Protein Names   
Glandular kallikrein KLK14; mGK14; Kallikrein related-peptidase 14
 Protein Family    Kallikrein
 UniProt Gene Name    Klk14 [Similar Products]
 UniProt Synonym Gene Names    Gk14; mGK14 [Similar Products]
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 NCBI Summary for Klk14    This gene encodes a member of the kallikrein subfamily of serine proteases that have diverse physiological functions such as regulation of blood pressure and desquamation. The encoded protein is a precursor that undergoes proteolytic cleavage of the activation peptide to generate the functional enzyme. The encoded enzyme was found to activate the complement pathway by cleavage of C3 to release C3a anaphylotoxin. This gene is one of the several glandular kallikrein genes located in a cluster on chromosome 7. [provided by RefSeq, Aug 2015]
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 UniProt Comments for Klk14    Serine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity. May activate/inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1, KLK3, KLK5 and KLK11. May function in seminal clot liquefaction through direct cleavage of the semenogelin SEMG1 and SEMG2 and activation of KLK3. May function through desmoglein DSG1 cleavage in epidermal desquamation a process by which the most superficial corneocytes are shed from the skin surface. May be involved in several aspects of tumor progression including growth, invasion and angiogenesis ().
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Product References and Citations for Klk14 recombinant protein

   "Taxon-specific evolution of glandular kallikrein genes and identification of a progenitor of prostate-specific antigen." Olsson A.Y., Lilja H., Lundwall A. Genomics 84:147-156(2004)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with Klk14 recombinant proteinOrgans/Tissues associated with Klk14 recombinant protein
 Disease Name  Pubmed Publications
 Digestive System Diseases Antibodies  >2 publications with Klk14 and Digestive System Diseases
 Dog Diseases Antibodies  >1 publications with Klk14 and Dog Diseases
 Organ/Tissue Name  Pubmed Publications
 Mammary Gland Antibodies  >1 publications with Klk14 and Mammary Gland
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