NP_115913.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
18,023 Da
NCBI Official Full Name
keratin-associated protein 4-4
NCBI Official Synonym Full Names
keratin associated protein 4-4
NCBI Official Synonym Symbols
KAP4.4; KAP4.13; KRTAP4.4; KRTAP4-13; KRTAP4.13 [Similar Products]
NCBI Protein Information
keratin-associated protein 4-4
UniProt Protein Name
Keratin-associated protein 4-4
UniProt Synonym Protein Names
Keratin-associated protein 4-13; Keratin-associated protein 4.13; Keratin-associated protein 4.4; Ultrahigh sulfur keratin-associated protein 4.13; Ultrahigh sulfur keratin-associated protein 4.4
UniProt Synonym Gene Names
NCBI Summary for KRTAP4-4
This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the ultrahigh sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008]
UniProt Comments for KRTAP4-4
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
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Pathways associated with KRTAP4-4 recombinant protein
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