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FGF7 recombinant protein :: Keratinocyte Growth Factor Human Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS650424 FGF7 recombinant protein
Unit / Price
0.01 mg  /  $470 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Keratinocyte Growth Factor Human (FGF7), Recombinant Protein

 Also Known As   

Keratinocyte Growth Factor, Recombinant Human (KGF, Fibroblast Growth Factor 7, FGF-7) (Human 293 Cells)

 Product Gene Name   

FGF7 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 15; NC_000015.9 (49715375..49779523). Location: 15q21.2
 OMIM    148180
 3D Structure    ModBase 3D Structure for P21781
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 Purity/Purification    Highly Purified
90% as determined by SDS-PAGE and HPLC.
 Form/Format    Supplied as a lyophilized powder from 10mM Tris pH 7.4, 700mM NaCl. Reconstitute with sterile dH2O, 0.1% endotoxin-free recombinant HSA.
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 Specific Activity    ~5ng/ml ED50
 Endotoxin Level    1EU/ug
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 Preparation and Storage    Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O, 0.1% endotoxin-free recombinant HSA. Aliquot and store at -20 degree C. Reconstituted product is stable for 6 months at 4 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of FGF7 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for FGF7 recombinant protein    Growth Factors, Cytokines; Growth Factors-KGF
NCBI/Uniprot data below describe general gene information for FGF7. It may not necessarily be applicable to this product.
 NCBI GI #    4503705
 NCBI GeneID    2252
 NCBI Accession #    NP_002000.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002009.3 [Other Products]
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 UniProt Primary Accession #    P21781 [Other Products]
 UniProt Related Accession #    P21781; Q6FGV5; Q6RK68; Q96FG5 [Other Products]
 Molecular Weight    18kD and 25 to 35kD dimer, glycosylated. [Similar Products]
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 NCBI Official Full Name    keratinocyte growth factor
 NCBI Official Synonym Full Names    fibroblast growth factor 7
 NCBI Official Symbol    FGF7 [Similar Products]
 NCBI Official Synonym Symbols   
KGF; HBGF-7
[Similar Products]
 NCBI Protein Information    keratinocyte growth factor; FGF-7; OTTHUMP00000162252; heparin-binding growth factor 7
 UniProt Protein Name    Keratinocyte growth factor
 UniProt Synonym Protein Names   
Fibroblast growth factor 7; FGF-7; Heparin-binding growth factor 7
 Protein Family    Fibroblast growth factor
 UniProt Gene Name    FGF7 [Similar Products]
 UniProt Synonym Gene Names    KGF [Similar Products]
 UniProt Entry Name    FGF7_HUMAN
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 NCBI Summary for FGF7    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. [provided by RefSeq]
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 UniProt Comments for FGF7    Function: Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation.

Subunit structure: Interacts with FGFBP1. Ref.4

Subcellular location: Secreted.

Tissue specificity: Epithelial cell.

Sequence similarities: Belongs to the heparin-binding growth factors family.
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 Research Articles on FGF7    1. Carcinoma-associated fibroblasts promotes the proliferation of a lingual carcinoma cell line by secreting keratinocyte growth factor.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FGF7 recombinant proteinPathways associated with FGF7 recombinant protein
 Reference Product  PubMed Publications
 FGFR2 recombinant protein  >234 publications with FGF7 and FGFR2
 FGFR1 recombinant protein  >56 publications with FGF7 and FGFR1
 FGFR3 recombinant protein  >25 publications with FGF7 and FGFR3
 FGFR4 recombinant protein  >17 publications with FGF7 and FGFR4
 COL1A1 recombinant protein  >1 publications with FGF7 and COL1A1
 Products by Pathway  Pathway Diagram
 Downstream Signaling Of Activated FGFR Pathway antibodies  Downstream Signaling Of Activated FGFR Pathway Diagram
 FGFR Ligand Binding And Activation Pathway antibodies  FGFR Ligand Binding And Activation Pathway Diagram
 FGFR2 Ligand Binding And Activation Pathway antibodies  FGFR2 Ligand Binding And Activation Pathway Diagram
 FGFR2b Ligand Binding And Activation Pathway antibodies  FGFR2b Ligand Binding And Activation Pathway Diagram
 FRS2-mediated Cascade Pathway antibodies  FRS2-mediated Cascade Pathway Diagram
 Glypican 3 Network Pathway antibodies  Glypican 3 Network Pathway Diagram
 IRS-mediated Signalling Pathway antibodies  IRS-mediated Signalling Pathway Diagram
 IRS-related Events Pathway antibodies  IRS-related Events Pathway Diagram
 Insulin Receptor Signalling Cascade Pathway antibodies  Insulin Receptor Signalling Cascade Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
Diseases associated with FGF7 recombinant proteinOrgans/Tissues associated with FGF7 recombinant protein
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >159 publications with FGF7 and Neoplasms
 Carcinoma Antibodies  >68 publications with FGF7 and Carcinoma
 Lung Injury Antibodies  >60 publications with FGF7 and Lung Injury
 Respiratory Tract Diseases Antibodies  >58 publications with FGF7 and Respiratory Tract Diseases
 Lung Diseases Antibodies  >57 publications with FGF7 and Lung Diseases
 Skin Diseases Antibodies  >49 publications with FGF7 and Skin Diseases
 Inflammation Antibodies  >44 publications with FGF7 and Inflammation
 Fibrosis Antibodies  >33 publications with FGF7 and Fibrosis
 Intestinal Diseases Antibodies  >32 publications with FGF7 and Intestinal Diseases
 Mucositis Antibodies  >31 publications with FGF7 and Mucositis
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >164 publications with FGF7 and Lung
 Skin Antibodies  >151 publications with FGF7 and Skin
 Embryonic Tissue Antibodies  >104 publications with FGF7 and Embryonic Tissue
 Prostate Antibodies  >70 publications with FGF7 and Prostate
 Intestine Antibodies  >67 publications with FGF7 and Intestine
 Bone Antibodies  >61 publications with FGF7 and Bone
 Vascular Antibodies  >46 publications with FGF7 and Vascular
 Kidney Antibodies  >37 publications with FGF7 and Kidney
 Muscle Antibodies  >37 publications with FGF7 and Muscle
 Eye Antibodies  >30 publications with FGF7 and Eye
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