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LYPLA1 recombinant protein

Scan QR to view Datasheet Catalog #    MBS203417
SDS-Page
Unit / Price
0.1 mg  /  $310 +1 FREE 8GB USB
0.5 mg  /  $720 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LYPLA1, Recombinant Protein

★Popular Item★
 Also Known As   

LYPLA1, 1-230aa, Mouse, His tag, E Coli

 Product Synonym Names    Acyl-protein thioesterase 1; lysophospholipase 1; Pla1a; APT-1; LysoPLA I; LPL-I; APT1
 Product Gene Name   

LYPLA1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHHHHH SSGLVPRGSH MCGNNMSAPM PAVVPAARKA TAAVIFLHGL GDTGHGWAEA FAGIKSPHIK YICPHAPVMP VTLNMNMAMP SWFDIVGLSP DSQEDESGIK QAAETVKALI DQEVKNGIPS NRIILGGFSQ GGALSLYTAL TTQQKLAGVT ALSCWLPLRA SFSQGPINSA NRDISVLQCH GDCDPLVPLM FGSLTVERLK ALINPANVTF KIYEGMMHSS CQQEMMDVKH FIDKLLPPID
 3D Structure    ModBase 3D Structure for P97823
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 Host    E Coli
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 Purity/Purification    > 90% by SDS-PAGE
 Form/Format    Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol, 0.1M NaCl, 1mM DTT
 Concentration    0.5 mg/ml (determined by Bradford assay) (lot specific)
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 Antigen Species    mouse
 Tag Information    His-tag
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of LYPLA1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for LYPLA1 recombinant protein

   LYPLA1 is lysophospholipase that acts on biological membranes to regulate the multifunctional lysophospholipids. This protein hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS and also has depalmitoylating activity. Recombinant mouse LYPLA1 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques
 Product Categories/Family for LYPLA1 recombinant protein    Metabolism
 Applications Tested/Suitable for LYPLA1 recombinant protein   

SDS-PAGE

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 SDS-Page of LYPLA1 recombinant protein    LYPLA1 recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for LYPLA1. It may not necessarily be applicable to this product.
 NCBI GI #    6678760
 NCBI GeneID    18777
 NCBI Accession #    NP_032892 [Other Products]
 NCBI GenBank Nucleotide #    NM_008866.3 [Other Products]
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 UniProt Primary Accession #    P97823 [Other Products]
 UniProt Secondary Accession #    Q3TJZ0; Q7TPX1; Q8BWM6 [Other Products]
 UniProt Related Accession #    P97823 [Other Products]
 Molecular Weight    26.8 kDa (250aa), confirmed by MALDI-TOF
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 NCBI Official Full Name    acyl-protein thioesterase 1 isoform 1
 NCBI Official Synonym Full Names    lysophospholipase 1
 NCBI Official Symbol    Lypla1 [Similar Products]
 NCBI Official Synonym Symbols   
APT-1; LPL-I; Pla1a; Gm39587
[Similar Products]
 NCBI Protein Information    acyl-protein thioesterase 1
 UniProt Protein Name    Acyl-protein thioesterase 1
 UniProt Synonym Protein Names   
Lysophospholipase 1; Lysophospholipase I; LPL-I; LysoPLA I
 UniProt Gene Name    Lypla1 [Similar Products]
 UniProt Synonym Gene Names    Apt1; Pla1a; APT-1; LPL-I; LysoPLA I [Similar Products]
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 UniProt Comments for LYPLA1    Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Has low lysophospholipase activity ().
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Product References and Citations for LYPLA1 recombinant protein

   Schaloske R.H., et al. (2006) Biochim Biophys Acta. 1761:1246-1259.; Hiraoka M., et al. (2002) J. Biol. Chem 277:10090-10099.;
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 Research Articles on LYPLA1    1. Data indicate that thioesterases APT1/APT2 depalmitoylate nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) and zDHHC17 is the strongest candidate palmitoyltransferase for NMNAT2.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with LYPLA1 recombinant proteinPathways associated with LYPLA1 recombinant protein
 Reference Product  PubMed Publications
 Lpcat2 recombinant protein  >1 publications with LYPLA1 and Lpcat2
 Products by Pathway  Pathway Diagram
 Choline Metabolism In Cancer Pathway antibodies  Choline Metabolism In Cancer Pathway Diagram
 Choline Metabolism In Cancer Pathway antibodies  Choline Metabolism In Cancer Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Nitric Oxide Pathway antibodies  Metabolism Of Nitric Oxide Pathway Diagram
 ENOS Activation Pathway antibodies  ENOS Activation Pathway Diagram
 ENOS Activation And Regulation Pathway antibodies  ENOS Activation And Regulation Pathway Diagram
Diseases associated with LYPLA1 recombinant proteinOrgans/Tissues associated with LYPLA1 recombinant protein
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >3 publications with LYPLA1 and Carcinoma
 Death Antibodies  >2 publications with LYPLA1 and Death
 Hyperplasia Antibodies  >2 publications with LYPLA1 and Hyperplasia
 Neoplasm Metastasis Antibodies  >1 publications with LYPLA1 and Neoplasm Metastasis
 Cardiovascular Diseases Antibodies  >1 publications with LYPLA1 and Cardiovascular Diseases
 Neoplasms, Experimental Antibodies  >1 publications with LYPLA1 and Neoplasms, Experimental
 Atherosclerosis Antibodies  >1 publications with LYPLA1 and Atherosclerosis
 Urinary Bladder Neoplasms Antibodies  >1 publications with LYPLA1 and Urinary Bladder Neoplasms
 Hypertension Antibodies  >1 publications with LYPLA1 and Hypertension
 Necrosis Antibodies  >1 publications with LYPLA1 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >7 publications with LYPLA1 and Blood
 Brain Antibodies  >6 publications with LYPLA1 and Brain
 Kidney Antibodies  >4 publications with LYPLA1 and Kidney
 Lung Antibodies  >1 publications with LYPLA1 and Lung
 Spleen Antibodies  >1 publications with LYPLA1 and Spleen
 Intestine Antibodies  >1 publications with LYPLA1 and Intestine
 Bladder Antibodies  >1 publications with LYPLA1 and Bladder
 Skin Antibodies  >1 publications with LYPLA1 and Skin
 Liver Antibodies  >1 publications with LYPLA1 and Liver
 Thymus Antibodies  >1 publications with LYPLA1 and Thymus
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