NP_002290.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
218,587 Da
NCBI Official Full Name
lactase-phlorizin hydrolase preproprotein
NCBI Official Synonym Full Names
lactase
NCBI Protein Information
lactase-phlorizin hydrolase
UniProt Protein Name
Lactase-phlorizin hydrolase
UniProt Synonym Protein Names
Lactase-glycosylceramidaseIncluding the following 2 domains:Lactase (EC:3.2.1.108)Phlorizin hydrolase (EC:3.2.1.62)
UniProt Synonym Gene Names
NCBI Summary for LCT
The protein encoded by this gene belongs to the glycosyl hydrolase 1 family of proteins. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme is integral to the plasma membrane and has both phlorizin hydrolase activity and lactase activity. Mutations in this gene are associated with congenital lactase deficiency. Polymorphisms in this gene are associated with lactase persistence, in which intestinal lactase activity persists at childhood levels into adulthood. [provided by RefSeq, Jan 2016]
UniProt Comments for LCT
LPH splits lactose in the small intestine.
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Pathways associated with LCT recombinant protein
Diseases associated with LCT recombinant protein
Organs/Tissues associated with LCT recombinant protein
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