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LAMC1 recombinant protein :: Laminin Gamma 1 (LAMC1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2010250 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $145 +1 FREE 8GB USB
0.05 mg  /  $270 +1 FREE 8GB USB
0.1 mg  /  $420 +1 FREE 8GB USB
0.2 mg  /  $515 +1 FREE 8GB USB
0.5 mg  /  $995 +1 FREE 8GB USB
1 mg  /  $1,480 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Laminin Gamma 1 (LAMC1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Laminin Gamma 1 (LAMC1)

 Product Gene Name   

LAMC1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 1; NC_000067.6 (153218922..153332786, complement). Location: 1 G3; 1 65.3 cM
 3D Structure    ModBase 3D Structure for P02468
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 Host    E. coli
 Species Reactivity    Mouse
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 Purity/Purification    >95%
 Form/Format    20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300
 Concentration    Original Concentration: 200g/mL (lot specific)
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 Source    Prokaryotic expression
 Residues    Glu1228~Arg1404
 Tags    N-terminal His-Tag
 Subcellular Location    Secreted, extracellular space, extracellular matrix, basement membrane
 Traits    Freeze-dried powder
 Predicted isoelectric point    5.7
 Predicted Molecular Mass    21.4kDa
 Accurate Molecular Mass    21kDa as determined by SDS-PAGE reducing conditions
 Usage    Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8C for one month.
Aliquot and store at -80C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of LAMC1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for LAMC1 recombinant protein   

Positive Control; Immunogen; SDS-PAGE; WB
(May be suitable for use in other assays to be determined by the end user.)

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 Sequence of LAMC1 recombinant protein    LAMC1 recombinant protein Sequence image
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 SDS-PAGE of LAMC1 recombinant protein    LAMC1 recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for LAMC1. It may not necessarily be applicable to this product.
 NCBI GI #    126370
 NCBI GeneID    226519
 NCBI Accession #    P02468.2 [Other Products]
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 UniProt Primary Accession #    P02468 [Other Products]
 UniProt Related Accession #    P02468 [Other Products]
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 NCBI Official Full Name    Laminin subunit gamma-1
 NCBI Official Synonym Full Names    laminin, gamma 1
 NCBI Official Symbol    Lamc1 [Similar Products]
 NCBI Official Synonym Symbols   
Lamb2
[Similar Products]
 NCBI Protein Information    laminin subunit gamma-1; S-LAM gamma; laminin B2 chain; S-laminin subunit gamma; laminin-1 subunit gamma; laminin-2 subunit gamma; laminin-3 subunit gamma; laminin-4 subunit gamma; laminin-6 subunit gamma; laminin-7 subunit gamma; laminin-8 subunit gamma; laminin-9 subunit gamma; laminin-10 subunit gamma; laminin-11 subunit gamma
 UniProt Protein Name    Laminin subunit gamma-1
 UniProt Synonym Protein Names   
Laminin B2 chain; Laminin-1 subunit gamma; Laminin-10 subunit gamma; Laminin-11 subunit gamma; Laminin-2 subunit gamma; Laminin-3 subunit gamma; Laminin-4 subunit gamma; Laminin-6 subunit gamma; Laminin-7 subunit gamma; Laminin-8 subunit gamma; Laminin-9 subunit gamma; S-laminin subunit gamma
 Protein Family    Laminin
 UniProt Gene Name    Lamc1 [Similar Products]
 UniProt Synonym Gene Names    Lamb-2; Lamc-1; S-LAM gamma [Similar Products]
 UniProt Entry Name    LAMC1_MOUSE
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 UniProt Comments for LAMC1    LAMC1: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Cellular Component: extracellular matrix; proteinaceous extracellular matrix; laminin-1 complex; laminin-10 complex; extracellular region; basement membrane; basal lamina

Molecular Function: protein binding; extracellular matrix structural constituent; glycosphingolipid binding

Biological Process: extracellular matrix disassembly; cell migration; hemidesmosome assembly; protein complex assembly; cell adhesion; neurite development
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 Research Articles on LAMC1    1. LNgamma1-knockout mice present with intracerebral hemorrhage in adulthood.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with LAMC1 recombinant proteinOrgans/Tissues associated with LAMC1 recombinant protein
 Products by Pathway  Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 ECM Proteoglycans Pathway antibodies  ECM Proteoglycans Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >17 publications with LAMC1 and Embryonic Tissue
 Kidney Antibodies  >7 publications with LAMC1 and Kidney
 Eye Antibodies  >6 publications with LAMC1 and Eye
 Blood Antibodies  >5 publications with LAMC1 and Blood
 Extraembryonic Tissue Antibodies  >3 publications with LAMC1 and Extraembryonic Tissue
 Uterus Antibodies  >3 publications with LAMC1 and Uterus
 Brain Antibodies  >3 publications with LAMC1 and Brain
 Lung Antibodies  >2 publications with LAMC1 and Lung
 Skin Antibodies  >2 publications with LAMC1 and Skin
 Heart Antibodies  >2 publications with LAMC1 and Heart
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