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LAMC3 recombinant protein :: Laminin Gamma 3 (LAMC3) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2010373 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
SDS-PAGE
Unit / Price
0.01 mg  /  $200 +1 FREE 8GB USB
0.05 mg  /  $430 +1 FREE 8GB USB
0.1 mg  /  $665 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Laminin Gamma 3 (LAMC3), Recombinant Protein

 Also Known As   

Recombinant Laminin Gamma 3 (LAMC3)

 Product Gene Name   

LAMC3 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSG SEF- GFYGNAFSGR ADDCQPCPCP GQSACATIPE SGDVVCTHCP PGQRGRRCES CEDGFFGDPL GLSGAPQPCR RCQCSGNVDL NAVGNCDPHS GHCLRCLYNT TGAHCEHCRE GFYGSAVATR PVDKC
 Chromosome Location    Chromosome: 2; NC_000068.7 (31887281..31946535). Location: 2 B; 2
 3D Structure    ModBase 3D Structure for Q9R0B6
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 Host    E Coli
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 Purity/Purification    > 95%
 Form/Format    Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
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 Organism    Mus musculus (Mouse)
 Expression System    Prokaryotic expression
 Residues    Gly751~Cys875 (Accession # Q9R0B6) with N-terminal His-Tag
 Endotoxin Level    <1.0EU per 1ug (determined by the LAL method)
 Reconstitution    Reconstitute in sterile PBS, pH7.2-pH7.4.
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 Preparation and Storage    Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of LAMC3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for LAMC3 recombinant protein

   About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
 Applications Tested/Suitable for LAMC3 recombinant protein   

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

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 SDS-PAGE of LAMC3 recombinant protein    LAMC3 recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for LAMC3. It may not necessarily be applicable to this product.
 NCBI GI #    66392579
 NCBI GeneID    23928
 NCBI Accession #    NP_035966.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_011836.3 [Other Products]
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 UniProt Primary Accession #    Q9R0B6 [Other Products]
 UniProt Secondary Accession #    Q4VAI3; Q9WTW6 [Other Products]
 UniProt Related Accession #    Q9R0B6 [Other Products]
 Molecular Weight    14.7kDa
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 NCBI Official Full Name    laminin subunit gamma-3
 NCBI Official Synonym Full Names    laminin gamma 3
 NCBI Official Symbol    Lamc3 [Similar Products]
 NCBI Official Synonym Symbols   
AI562206; AW240805
[Similar Products]
 NCBI Protein Information    laminin subunit gamma-3; laminin-12 subunit gamma; laminin-14 subunit gamma; laminin-15 subunit gamma
 UniProt Protein Name    Laminin subunit gamma-3
 UniProt Synonym Protein Names   
Laminin-12 subunit gamma; Laminin-14 subunit gamma; Laminin-15 subunit gamma
 Protein Family    Laminin
 UniProt Gene Name    Lamc3 [Similar Products]
 UniProt Entry Name    LAMC3_MOUSE
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 UniProt Comments for LAMC3    LAMC3: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Defects in LAMC3 are the cause of cortical malformations occipital (OCCM). OCCM is a disease in which affected individuals develop seizures, sometimes associated with transient visual changes. Brain MRI shows both pachygyria and polymicrogyria restricted to the lateral occipital lobes.

Protein type: Motility/polarity/chemotaxis; Extracellular matrix; Secreted; Secreted, signal peptide

Cellular Component: proteinaceous extracellular matrix; extracellular region; basement membrane

Biological Process: cellular morphogenesis during differentiation; visual perception; retina development in camera-type eye; cell adhesion; astrocyte development
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 Research Articles on LAMC3    1. Deletion of Lamb2 and Lamc3 genes affects astrocyte migration and spatial patterning in the retina.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with LAMC3 recombinant proteinDiseases associated with LAMC3 recombinant protein
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Laminin Interactions Pathway antibodies  Laminin Interactions Pathway Diagram
 Non-integrin Membrane-ECM Interactions Pathway antibodies  Non-integrin Membrane-ECM Interactions Pathway Diagram
 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >3 publications with LAMC3 and Mental Disorders
 Neoplasms Antibodies  >3 publications with LAMC3 and Neoplasms
 Child Development Disorders, Pervasive Antibodies  >2 publications with LAMC3 and Child Development Disorders, Pervasive
 Breast Neoplasms Antibodies  >1 publications with LAMC3 and Breast Neoplasms
 Intracranial Hypertension Antibodies  >1 publications with LAMC3 and Intracranial Hypertension
 Urinary Bladder Neoplasms Antibodies  >1 publications with LAMC3 and Urinary Bladder Neoplasms
 Hydrocephalus Antibodies  >1 publications with LAMC3 and Hydrocephalus
 Central Nervous System Diseases Antibodies  >1 publications with LAMC3 and Central Nervous System Diseases
 Neurobehavioral Manifestations Antibodies  >1 publications with LAMC3 and Neurobehavioral Manifestations
 Maxillofacial Abnormalities Antibodies  >1 publications with LAMC3 and Maxillofacial Abnormalities
Organs/Tissues associated with LAMC3 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >6 publications with LAMC3 and Brain
 Testis Antibodies  >5 publications with LAMC3 and Testis
 Skin Antibodies  >4 publications with LAMC3 and Skin
 Eye Antibodies  >4 publications with LAMC3 and Eye
 Lung Antibodies  >2 publications with LAMC3 and Lung
 Heart Antibodies  >2 publications with LAMC3 and Heart
 Embryonic Tissue Antibodies  >2 publications with LAMC3 and Embryonic Tissue
 Kidney Antibodies  >1 publications with LAMC3 and Kidney
 Salivary Gland Antibodies  >1 publications with LAMC3 and Salivary Gland
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