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LAMA1 recombinant protein :: Laminin subunit alpha-1 (LAMA1), partial Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS956514 LAMA1 recombinant protein
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Laminin subunit alpha-1 (LAMA1), partial, Recombinant Protein

 Also Known As   

Recombinant Human Laminin subunit alpha-1 (LAMA1), partial

 Product Synonym Names    Laminin subunit alpha-1; Laminin A chain; Laminin-1 subunit alpha; Laminin-3 subunit alpha; S-laminin subunit alpha; S-LAM alpha
 Product Gene Name   

LAMA1 recombinant protein

[Similar Products]
 Product Synonym Gene Name    LAMA1; LAMA [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    150320
 3D Structure    ModBase 3D Structure for P25391
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of LAMA1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for LAMA1 recombinant protein

   LAMA1; LAMA
NCBI/Uniprot data below describe general gene information for LAMA1. It may not necessarily be applicable to this product.
 NCBI GI #    38788416
 NCBI GeneID    284217
 NCBI Accession #    NP_005550.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_005559.3 [Other Products]
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 UniProt Primary Accession #    P25391 [Other Products]
 UniProt Related Accession #    P25391 [Other Products]
 Molecular Weight    337,084 Da
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 NCBI Official Full Name    laminin subunit alpha-1
 NCBI Official Synonym Full Names    laminin, alpha 1
 NCBI Official Symbol    LAMA1 [Similar Products]
 NCBI Official Synonym Symbols   
LAMA; S-LAM-alpha
[Similar Products]
 NCBI Protein Information    laminin subunit alpha-1; S-LAM alpha; laminin A chain; S-laminin subunit alpha; laminin-3 subunit alpha
 UniProt Protein Name    Laminin subunit alpha-1
 UniProt Synonym Protein Names   
Laminin A chain; Laminin-1 subunit alpha; Laminin-3 subunit alpha; S-laminin subunit alpha; S-LAM alpha
 Protein Family    Laminin
 UniProt Gene Name    LAMA1 [Similar Products]
 UniProt Synonym Gene Names    LAMA; S-LAM alpha [Similar Products]
 UniProt Entry Name    LAMA1_HUMAN
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 NCBI Summary for LAMA1    This gene encodes one of the alpha 1 subunits of laminin. The laminins are a family of extracellular matrix glycoproteins that have a heterotrimeric structure consisting of an alpha, beta and gamma chain. These proteins make up a major component of the basement membrane and have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Mutations in this gene may be associated with Poretti-Boltshauser syndrome. [provided by RefSeq, Sep 2014]
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 UniProt Comments for LAMA1    LAMA1: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.

Protein type: Extracellular matrix; Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 18p11.3

Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular space; laminin-1 complex; laminin-3 complex; extracellular region; basement membrane; intercellular junction

Molecular Function: protein binding; extracellular matrix structural constituent; glycosphingolipid binding; receptor binding

Biological Process: regulation of cell adhesion; axon guidance; extracellular matrix organization and biogenesis; cell surface receptor linked signal transduction; regulation of embryonic development; morphogenesis of an epithelial sheet; establishment of epithelial cell polarity; cell adhesion; regulation of cell migration

Disease: Poretti-boltshauser Syndrome
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 Research Articles on LAMA1    1. Studies indicate that progenitor endothelial cells (ECs), endothelial colony-forming cells (ECFCs), deposit collagen IV, fibronectin, and laminin.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with LAMA1 recombinant proteinPathways associated with LAMA1 recombinant protein
 Reference Product  PubMed Publications
 LAMC1 recombinant protein  >6 publications with LAMA1 and LAMC1
 LAMB1 recombinant protein  >5 publications with LAMA1 and LAMB1
 LAMA5 recombinant protein  >3 publications with LAMA1 and LAMA5
 ITGA3 recombinant protein  >2 publications with LAMA1 and ITGA3
 ITGA6 recombinant protein  >1 publications with LAMA1 and ITGA6
 Products by Pathway  Pathway Diagram
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 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
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 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 ECM Proteoglycans Pathway antibodies  ECM Proteoglycans Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
Diseases associated with LAMA1 recombinant proteinOrgans/Tissues associated with LAMA1 recombinant protein
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with LAMA1 and Neoplasms
 Fibrosis Antibodies  >2 publications with LAMA1 and Fibrosis
 Liver Diseases Antibodies  >1 publications with LAMA1 and Liver Diseases
 Leukemia, Myeloid Antibodies  >1 publications with LAMA1 and Leukemia, Myeloid
 Brain Diseases Antibodies  >1 publications with LAMA1 and Brain Diseases
 Fatty Liver Antibodies  >1 publications with LAMA1 and Fatty Liver
 Necrosis Antibodies  >1 publications with LAMA1 and Necrosis
 Inflammation Antibodies  >1 publications with LAMA1 and Inflammation
 Skin Diseases Antibodies  >1 publications with LAMA1 and Skin Diseases
 Non-alcoholic Fatty Liver Disease Antibodies  >1 publications with LAMA1 and Non-alcoholic Fatty Liver Disease
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >10 publications with LAMA1 and Embryonic Tissue
 Blood Antibodies  >8 publications with LAMA1 and Blood
 Brain Antibodies  >6 publications with LAMA1 and Brain
 Eye Antibodies  >6 publications with LAMA1 and Eye
 Muscle Antibodies  >4 publications with LAMA1 and Muscle
 Placenta Antibodies  >3 publications with LAMA1 and Placenta
 Skin Antibodies  >3 publications with LAMA1 and Skin
 Uterus Antibodies  >3 publications with LAMA1 and Uterus
 Bone Antibodies  >3 publications with LAMA1 and Bone
 Intestine Antibodies  >2 publications with LAMA1 and Intestine
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