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LRRFIP1 recombinant protein :: Leucine-rich repeat flightless-interacting protein 1 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1265458
SDS-PAGE
Unit / Price
0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $855 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $990 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,145 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,235 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,255 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,300 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,805 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,875 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,970 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,400 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Leucine-rich repeat flightless-interacting protein 1 (LRRFIP1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant human Leucine-rich repeat flightless-interacting protein 1

 Product Gene Name   

LRRFIP1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-314aa; Partial of Isoform 3
 Sequence    MTSPAAAQSR EIDCLSPEAQ KLAEARLAAK RAARAEAREI RMKELERQQK EVEERPEKDF TEKGSRNMPG LSAATLASLG GTSSRRGSGD TSISIDTEAS IREIKDSLAE VEEKYKKAMV SNAQLDNEKT NFMYQVDTLK DMLLELEEQL AESRRQYEEK NKEFEREKHA HSILQFQFAE VKEALKQREE MLEKHGIILN SEIATNGETS DTLNNVGYQG PTKMTKEELN ALKSTGDGTL GRASEVEVKN EIVANVGKRE ILHNTEKEQH TEDTVKDCVD IEVFPAGENT EDQKSSEDTA PFLGTLAGAT YEEQSLSTCS LDR
 Chromosome Location    Chromosome: 2; NC_000002.11 (238536224..238690290). Location: 2q37.3
 OMIM    603256
 3D Structure    ModBase 3D Structure for Q32MZ4
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C. For extended storage, conserve at -20 or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of LRRFIP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for LRRFIP1 recombinant protein

   Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
 Product Categories/Family for LRRFIP1 recombinant protein    Transcription
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 SDS-PAGE of LRRFIP1 recombinant protein    LRRFIP1 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for LRRFIP1. It may not necessarily be applicable to this product.
 NCBI GI #    212276078
 NCBI GeneID    9208
 NCBI Accession #    NP_001131022.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001137550.1 [Other Products]
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 UniProt Primary Accession #    Q32MZ4 [Other Products]
 UniProt Secondary Accession #    O75766; O75799; Q32MZ5; Q53T49; Q6PKG2; Q9Y607; E9PGZ2 [Other Products]
 UniProt Related Accession #    Q32MZ4 [Other Products]
 Molecular Weight    89,253 Da [Similar Products]
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 NCBI Official Full Name    leucine-rich repeat flightless-interacting protein 1 isoform 1
 NCBI Official Synonym Full Names    leucine rich repeat (in FLII) interacting protein 1
 NCBI Official Symbol    LRRFIP1 [Similar Products]
 NCBI Official Synonym Symbols   
GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1
[Similar Products]
 NCBI Protein Information    leucine-rich repeat flightless-interacting protein 1; GC-binding factor 2; NEDD8-conjugating enzyme; TAR RNA-interacting protein; LRR FLII-interacting protein 1
 UniProt Protein Name    Leucine-rich repeat flightless-interacting protein 1
 UniProt Synonym Protein Names   
GC-binding factor 2; TAR RNA-interacting protein
 Protein Family    Leucine-rich repeat flightless-interacting protein
 UniProt Gene Name    LRRFIP1 [Similar Products]
 UniProt Synonym Gene Names    GCF2; TRIP; LRR FLII-interacting protein 1 [Similar Products]
 UniProt Entry Name    LRRF1_HUMAN
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 UniProt Comments for LRRFIP1    LRRFIP1: Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. Belongs to the LRRFIP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; RNA-binding

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: cytoskeleton; cytoplasm; plasma membrane; cytosol; nucleus

Molecular Function: protein binding; protein homodimerization activity; DNA binding; double-stranded RNA binding

Biological Process: regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; positive regulation of interferon type I production; innate immune response; negative regulation of transcription, DNA-dependent
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 Research Articles on LRRFIP1    1. The FLI-interacting domain of LRRFIP1 forms a classic parallel, homodimeric coiled coil with 10 heptad repeats and 22 helical turns.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with LRRFIP1 recombinant proteinPathways associated with LRRFIP1 recombinant protein
 Reference Product  PubMed Publications
 FLII recombinant protein  >4 publications with LRRFIP1 and FLII
 CTNNB1 recombinant protein  >3 publications with LRRFIP1 and CTNNB1
 MYD88 recombinant protein  >2 publications with LRRFIP1 and MYD88
 TFAP2A recombinant protein  >1 publications with LRRFIP1 and TFAP2A
 SLC1A2 recombinant protein  >1 publications with LRRFIP1 and SLC1A2
 GRIP1 recombinant protein  >1 publications with LRRFIP1 and GRIP1
 Products by Pathway  Pathway Diagram
 Cytosolic Sensors Of Pathogen-associated DNA Pathway antibodies  Cytosolic Sensors Of Pathogen-associated DNA Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 LRR FLII-interacting Protein 1 (LRRFIP1) Activates Type I IFN Production Pathway antibodies  LRR FLII-interacting Protein 1 (LRRFIP1) Activates Type I IFN Production Pathway Diagram
 Signaling By FGFR In Disease Pathway antibodies  Signaling By FGFR In Disease Pathway Diagram
 Signaling By FGFR Mutants Pathway antibodies  Signaling By FGFR Mutants Pathway Diagram
 Signaling By FGFR1 Fusion Mutants Pathway antibodies  Signaling By FGFR1 Fusion Mutants Pathway Diagram
 Signaling By FGFR1 Mutants Pathway antibodies  Signaling By FGFR1 Mutants Pathway Diagram
Diseases associated with LRRFIP1 recombinant proteinOrgans/Tissues associated with LRRFIP1 recombinant protein
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >4 publications with LRRFIP1 and Cardiovascular Diseases
 Neoplasms Antibodies  >4 publications with LRRFIP1 and Neoplasms
 Heart Diseases Antibodies  >3 publications with LRRFIP1 and Heart Diseases
 Inflammation Antibodies  >3 publications with LRRFIP1 and Inflammation
 Thrombosis Antibodies  >2 publications with LRRFIP1 and Thrombosis
 Necrosis Antibodies  >2 publications with LRRFIP1 and Necrosis
 Stroke Antibodies  >1 publications with LRRFIP1 and Stroke
 Breast Neoplasms Antibodies  >1 publications with LRRFIP1 and Breast Neoplasms
 Nervous System Diseases Antibodies  >1 publications with LRRFIP1 and Nervous System Diseases
 Atherosclerosis Antibodies  >1 publications with LRRFIP1 and Atherosclerosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >8 publications with LRRFIP1 and Blood
 Heart Antibodies  >4 publications with LRRFIP1 and Heart
 Muscle Antibodies  >3 publications with LRRFIP1 and Muscle
 Brain Antibodies  >3 publications with LRRFIP1 and Brain
 Adipose Tissue Antibodies  >2 publications with LRRFIP1 and Adipose Tissue
 Vascular Antibodies  >1 publications with LRRFIP1 and Vascular
 Testis Antibodies  >1 publications with LRRFIP1 and Testis
 Bone Marrow Antibodies  >1 publications with LRRFIP1 and Bone Marrow
 Bone Antibodies  >1 publications with LRRFIP1 and Bone
 Nerve Antibodies  >1 publications with LRRFIP1 and Nerve
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