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CYP4F2 recombinant protein :: Leukotriene-B (4) omega-hydroxylase 1 (CYP4F2) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS948523 CYP4F2 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $940 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,140 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,260 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,370 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,385 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,390 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,445 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,550 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,970 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,070 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,095 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,355 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,725 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Leukotriene-B (4) omega-hydroxylase 1 (CYP4F2), Recombinant Protein

 Also Known As   

Recombinant Human Leukotriene-B (4) omega-hydroxylase 1 (CYP4F2)

 Product Gene Name   

CYP4F2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    5-520aa, Full Length of Mature Protein
 Sequence    SLSWLGLWPV AASPWLLLLL VGASWLLAHV LAWTYAFYDN CRRLRCFPQP PRRNWFWGHQ GMVNPTEEGM RVLTQLVATY PQGFKVWMGP ISPLLSLCHP DIIRSVINAS AAIAPKDKFF YSFLEPWLGD GLLLSAGDKW SRHRRMLTPA FHFNILKPYM KIFNESVNIM HAKWQLLASE GSACLDMFEH ISLMTLDSLQ KCVFSFDSHC QEKPSEYIAA ILELSALVSK RHHEILLHID FLYYLTPDGQ RFRRACRLVH DFTDAVIQER RRTLPSQGVD DFLQAKAKSK TLDFIDVLLL SKDEDGKKLS DEDIRAEADT FMFEGHDTTA SGLSWVLYHL AKHPEYQERC RQEVQELLKD REPKEIEWDD LAHLPFLTMC MKESLRLHPP VPVISRHVTQ DIVLPDGRVI PKGIICLISV FGTHHNPAVW PDPEVYDPFR FDPENIKERS PLAFIPFSAG PRNCIGQTFA MAEMKVVLAL TLLRFRVLPD HTEPRRKPEL VLRAEGGLWL RVEPLS
 OMIM    122700
 3D Structure    ModBase 3D Structure for P78329
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of CYP4F2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for CYP4F2 recombinant protein

   This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F11, is approximately 16 kb away.
NCBI/Uniprot data below describe general gene information for CYP4F2. It may not necessarily be applicable to this product.
 NCBI GI #    13435391
 NCBI GeneID    8529
 NCBI Accession #    NP_001073.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_001082.4 [Other Products]
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 UniProt Primary Accession #    P78329 [Other Products]
 UniProt Secondary Accession #    Q16677; Q6NWT4; Q6NWT6; Q9NNZ0; Q9UIU8; A0A024R7K3; A8K425; B4DV75 [Other Products]
 UniProt Related Accession #    P78329 [Other Products]
 Molecular Weight    21,709 Da
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 NCBI Official Full Name    phylloquinone omega-hydroxylase CYP4F2
 NCBI Official Synonym Full Names    cytochrome P450 family 4 subfamily F member 2
 NCBI Official Symbol    CYP4F2 [Similar Products]
 NCBI Official Synonym Symbols   
CPF2
[Similar Products]
 NCBI Protein Information    phylloquinone omega-hydroxylase CYP4F2
 UniProt Protein Name    Phylloquinone omega-hydroxylase CYP4F2
 UniProt Synonym Protein Names   
20-hydroxyeicosatetraenoic acid synthase
 Protein Family    Phylloquinone omega-hydroxylase
 UniProt Gene Name    CYP4F2 [Similar Products]
 UniProt Synonym Gene Names    20-HETE synthase [Similar Products]
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 NCBI Summary for CYP4F2    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F11, is approximately 16 kb away. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CYP4F2    Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:19297519, PubMed:24138531). Also shows arachidonic acid omega-hydroxylase activity in kidney, by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), possibly influencing blood pressure control (PubMed:10660572, PubMed:17341693, PubMed:18574070). Also acts as a leukotriene-B4 omega-hydroxylase by mediating conversion of leukotriene-B4 (LTB4) to its omega-hydroxylated metabolite 20-hydroxyleukotriene-B4 (20-OH LTB4) (PubMed:8026587, PubMed:9799565).
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 Research Articles on CYP4F2    1. show that children on chronic warfarin therapy have low levels of vitamin K and vitamin K levels are linked to CYP4F2 genotype
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CYP4F2 recombinant proteinPathways associated with CYP4F2 recombinant protein
 Reference Product  PubMed Publications
 CYP2C9 recombinant protein  >126 publications with CYP4F2 and CYP2C9
 CYP2C19 recombinant protein  >22 publications with CYP4F2 and CYP2C19
 CYP2E1 recombinant protein  >14 publications with CYP4F2 and CYP2E1
 CYP2J2 recombinant protein  >10 publications with CYP4F2 and CYP2J2
 CYP2B6 recombinant protein  >6 publications with CYP4F2 and CYP2B6
 CYP2C8 recombinant protein  >5 publications with CYP4F2 and CYP2C8
 CYP2C18 recombinant protein  >4 publications with CYP4F2 and CYP2C18
 PTGS2 recombinant protein  >1 publications with CYP4F2 and PTGS2
 Products by Pathway  Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Cytochrome P450 - Arranged By Substrate Type Pathway antibodies  Cytochrome P450 - Arranged By Substrate Type Pathway Diagram
 Eicosanoids Pathway antibodies  Eicosanoids Pathway Diagram
 Fatty Acids Pathway antibodies  Fatty Acids Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
Diseases associated with CYP4F2 recombinant proteinOrgans/Tissues associated with CYP4F2 recombinant protein
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >56 publications with CYP4F2 and Cardiovascular Diseases
 Heart Diseases Antibodies  >15 publications with CYP4F2 and Heart Diseases
 Fatty Liver Antibodies  >14 publications with CYP4F2 and Fatty Liver
 Nervous System Diseases Antibodies  >13 publications with CYP4F2 and Nervous System Diseases
 Inflammation Antibodies  >10 publications with CYP4F2 and Inflammation
 Hemorrhage Antibodies  >10 publications with CYP4F2 and Hemorrhage
 Liver Diseases Antibodies  >9 publications with CYP4F2 and Liver Diseases
 Lung Diseases Antibodies  >6 publications with CYP4F2 and Lung Diseases
 Blood Coagulation Disorders Antibodies  >4 publications with CYP4F2 and Blood Coagulation Disorders
 Congenital Abnormalities Antibodies  >2 publications with CYP4F2 and Congenital Abnormalities
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >68 publications with CYP4F2 and Blood
 Liver Antibodies  >63 publications with CYP4F2 and Liver
 Kidney Antibodies  >23 publications with CYP4F2 and Kidney
 Brain Antibodies  >7 publications with CYP4F2 and Brain
 Muscle Antibodies  >6 publications with CYP4F2 and Muscle
 Intestine Antibodies  >5 publications with CYP4F2 and Intestine
 Skin Antibodies  >2 publications with CYP4F2 and Skin
 Prostate Antibodies  >2 publications with CYP4F2 and Prostate
 Bone Antibodies  >1 publications with CYP4F2 and Bone
 Connective Tissue Antibodies  >1 publications with CYP4F2 and Connective Tissue
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