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LPAR1 recombinant protein :: Lysophosphatidic acid receptor 1 (LPAR1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS964446 LPAR1 recombinant protein
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Lysophosphatidic acid receptor 1 (LPAR1), Recombinant Protein

 Also Known As   

Recombinant Sheep Lysophosphatidic acid receptor 1 (LPAR1)

 Product Synonym Names    Recombinant Lysophosphatidic acid receptor 1 (LPAR1); Lysophosphatidic acid receptor 1; LPA receptor 1; LPA-1; Lysophosphatidic acid receptor Edg-2
 Product Gene Name   

LPAR1 recombinant protein

[Similar Products]
 Product Synonym Gene Name    LPAR1; EDG-2, EDG2, LPA1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-393
 Sequence    MAAASTSSPV VSQPQFTAMN EPQCFYNESI AFFYNRSGKY LATEWNTVSK LVMGLGITVC IFIMLANLLV MVAIYVNRRF HFPIYYLMAN LAAADFFAGL AYFYLMFNTG PNTRRLTVST WLLRQGLIDT TVTASVANLL AIAIERHITV FRMQLHTRMS NRRVVVVIVV IWTMAIVMGA IPSVGWNCIC DIENCSNMAP LYSDSYLVFW AIFNLVTFVV MVVLYAHIFG YVRQRTMRMS RHSSGPRRNR DTMMSLLKTV VIVLGAFIIC WTPGLVLLLL DVCCPQCDVL AYEKFFLLLA EFNSAMNPII YSYRDKEMSA TFRQILCCQR SENTSGPTEG SDRSASSLNH TILAGVHSND HSVFRKETKM RGGHHLLRDE QPPPPERPGQ GRV
 Chromosome Location    Chromosome: 2; NC_019459.1 (12324949..12488421). Location: chromosome: 2
 3D Structure    ModBase 3D Structure for P46628
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Ovis aries (Sheep)
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 Preparation and Storage    Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of LPAR1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for LPAR1. It may not necessarily be applicable to this product.
 NCBI GI #    57164353
 NCBI GeneID    443346
 NCBI Accession #    NP_001009332.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001009332.1 [Other Products]
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 UniProt Primary Accession #    P46628 [Other Products]
 UniProt Related Accession #    P46628 [Other Products]
 Molecular Weight    44,433 Da [Similar Products]
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 NCBI Official Full Name    lysophosphatidic acid receptor 1
 NCBI Official Symbol    LPAR1 [Similar Products]
 NCBI Official Synonym Symbols   
EDG-2
[Similar Products]
 NCBI Protein Information    lysophosphatidic acid receptor 1; LPA-1; LPA receptor 1; endothelium differentiation gene 2; lysophosphatidic acid receptor Edg-2
 UniProt Protein Name    Lysophosphatidic acid receptor 1
 UniProt Synonym Protein Names   
Lysophosphatidic acid receptor Edg-2
 Protein Family    Lysophosphatidic acid receptor
 UniProt Gene Name    LPAR1 [Similar Products]
 UniProt Synonym Gene Names    EDG-2; EDG2; LPA1; LPA receptor 1; LPA-1 [Similar Products]
 UniProt Entry Name    LPAR1_SHEEP
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 UniProt Comments for LPAR1    Function: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation

By similarity.

Subunit structure: Interacts with RALA and ADRBK1

By similarity.

Subcellular location: Cell surface

By similarity. Cell membrane; Multi-pass membrane protein. Note: Prior to LPA treatment found predominantly at the cell surface but in the presence of LPA co-localizes with RALA in the endocytic vesicles

By similarity.

Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with LPAR1 recombinant proteinOrgans/Tissues associated with LPAR1 recombinant protein
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >7 publications with LPAR1 and Neoplasms
 Nervous System Diseases Antibodies  >3 publications with LPAR1 and Nervous System Diseases
 Pain Antibodies  >3 publications with LPAR1 and Pain
 Adenocarcinoma Antibodies  >2 publications with LPAR1 and Adenocarcinoma
 Fibrosis Antibodies  >2 publications with LPAR1 and Fibrosis
 Prostatic Diseases Antibodies  >2 publications with LPAR1 and Prostatic Diseases
 Carcinoma Antibodies  >2 publications with LPAR1 and Carcinoma
 Prostatic Neoplasms Antibodies  >2 publications with LPAR1 and Prostatic Neoplasms
 Carcinoma, Hepatocellular Antibodies  >1 publications with LPAR1 and Carcinoma, Hepatocellular
 Disease Models, Animal Antibodies  >1 publications with LPAR1 and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1 publications with LPAR1 and Bone
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