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Lamp2 recombinant protein :: Lysosome-associated membrane glycoprotein 2 (Lamp2) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS955098 Lamp2 recombinant protein
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Lysosome-associated membrane glycoprotein 2 (Lamp2), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Rat Lysosome-associated membrane glycoprotein 2 (Lamp2)

 Product Synonym Names    Recombinant Lysosome-associated membrane glycoprotein 2 (Lamp2); Lysosome-associated membrane glycoprotein 2; LAMP-2; Lysosome-associated membrane protein 2; CD107 antigen-like family member B LGP-110 LGP-96 Lysosomal membrane glycoprotein type B; LGP-B C
 Product Gene Name   

Lamp2 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Lamp2; Lamp-2 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    26-376
 Chromosome Location    Chromosome: X; NC_005120.3 (124809053..124852469, complement). Location: Xq11
 3D Structure    ModBase 3D Structure for P17046
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rattus norvegicus (Rat)
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 Preparation and Storage    Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Lamp2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Lamp2. It may not necessarily be applicable to this product.
 NCBI GI #    126382
 NCBI GeneID    24944
 NCBI Accession #    P17046.2 [Other Products]
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 UniProt Primary Accession #    P17046 [Other Products]
 UniProt Related Accession #    P17046 [Other Products]
 Molecular Weight    45,164 Da [Similar Products]
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 NCBI Official Full Name    Lysosome-associated membrane glycoprotein 2
 NCBI Official Synonym Full Names    lysosomal-associated membrane protein 2
 NCBI Official Symbol    Lamp2 [Similar Products]
 NCBI Protein Information    lysosome-associated membrane glycoprotein 2; LGP-B; LAMP-2; LGP-96; LGP-110; lysosomal membrane glycoprotein 2; CD107 antigen-like family member B; lysosomal membrane glycoprotein type B; lysosome-associated membrane protein 2
 UniProt Protein Name    Lysosome-associated membrane glycoprotein 2
 UniProt Synonym Protein Names   
CD107 antigen-like family member B; LGP-110; LGP-96; Lysosomal membrane glycoprotein type B
 Protein Family    Lysosome-associated membrane glycoprotein
 UniProt Gene Name    Lamp2 [Similar Products]
 UniProt Synonym Gene Names    Lamp-2; LAMP-2; Lysosome-associated membrane protein 2; LGP-B [Similar Products]
 UniProt Entry Name    LAMP2_RAT
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 NCBI Summary for Lamp2    intrinsic lysosomal membrane protein [RGD, Feb 2006]
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 UniProt Comments for Lamp2    Function: Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.

Subcellular location: Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note: This protein shuttles between lysosomes, endosomes, and the plasma membrane.

Post-translational modification: O- and N-glycosylated; some of the N-glycans attached to Lamp-2 are polylactosaminoglycans

By similarity.

Sequence similarities: Belongs to the LAMP family.
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 Research Articles on Lamp2    1. Chaperone-mediated autophagy is increased in rats with pilocarpine-induced status epilepticus through upregulation of de novo synthesis of lysosome-associated membrane protein 2a.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Lamp2 recombinant proteinOrgans/Tissues associated with Lamp2 recombinant protein
 Products by Pathway  Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Platelet Activation, Signaling And Aggregation Pathway antibodies  Platelet Activation, Signaling And Aggregation Pathway Diagram
 Platelet Degranulation Pathway antibodies  Platelet Degranulation Pathway Diagram
 Response To Elevated Platelet Cytosolic Ca2+ Pathway antibodies  Response To Elevated Platelet Cytosolic Ca2+ Pathway Diagram
 Senescence And Autophagy Pathway antibodies  Senescence And Autophagy Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >20 publications with Lamp2 and Brain
 Liver Antibodies  >19 publications with Lamp2 and Liver
 Kidney Antibodies  >9 publications with Lamp2 and Kidney
 Lung Antibodies  >7 publications with Lamp2 and Lung
 Spleen Antibodies  >4 publications with Lamp2 and Spleen
 Ovary Antibodies  >4 publications with Lamp2 and Ovary
 Eye Antibodies  >4 publications with Lamp2 and Eye
 Thymus Antibodies  >3 publications with Lamp2 and Thymus
 Embryonic Tissue Antibodies  >2 publications with Lamp2 and Embryonic Tissue
 Pancreas Antibodies  >2 publications with Lamp2 and Pancreas
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