P61507.1
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UniProt Primary Accession #
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NCBI Official Full Name
M-lycotoxin-Hc1a
UniProt Protein Name
M-lycotoxin-Hc1a
UniProt Synonym Protein Names
Lycotoxin I; Lycotoxin-1
UniProt Synonym Gene Names
UniProt Entry Name
LYT1_HOGCA
UniProt Comments for M-LCTX-Hc1a
Function: Forms pore that permeabilize the cell membrane. Promotes efflux of calcium from synaptosomes, causes hemolysis, and dissipates voltage gradients across muscle membrane. Potently inhibits the growth of bacteria, yeast and Leishmania. Is lethal to lepidopteran larvae. May function both in the prey capture strategy as well as protection from infectious organisms arising from prey ingestion. Ref.1 Ref.2
Subcellular location: Secreted. Target cell membrane. Note: Forms a transmembrane alpha-helix in the target cell membrane. Forms a membrane channel in the prey. Ref.2
Tissue specificity: Expressed by the venom gland.
Miscellaneous: Mutated toxins are expressed as transgene in yeasts. Yeasts containing transgenes cause lethality when feed to lepidopteran larvae (S.frugiperda).
Mass spectrometry: Molecular mass is 2843.4 Da from positions 1 - 25. Determined by MALDI. Ref.1
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Products associated with M-LCTX-Hc1a recombinant protein
Pathways associated with M-LCTX-Hc1a recombinant protein
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