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Cdc25a recombinant protein :: M-phase inducer phosphatase 1 (Cdc25a) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS961921 Cdc25a recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $950 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,145 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,270 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,380 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,395 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,400 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,455 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,560 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,995 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,085 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,105 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,375 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,740 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

M-phase inducer phosphatase 1 (Cdc25a), Recombinant Protein

 Also Known As   

Recombinant Rat M-phase inducer phosphatase 1 (Cdc25a)

 Product Gene Name   

Cdc25a recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-525aa, Full length protein
 Sequence    MELGPEPPHR RRLLFTCSPT PAPQPTGKVQ FGASRAGGLS PVTNLTVTMD QLEGLGSDYE KPMDVRNSSS LQRMGSSEST DSGFCLDSPG PLDSKENLEI SLRRINCLPQ KLLGCSPALK RSHSDSLDHD IFQLIDQDEN KENEAFEFKK PIRPASRGCL NAHVHEESKD PFTHRQNSAP ARMLSSNESD ISESGNFSPL FTPQSPVKAS LSDEDDGFID LLDGENLKND EETPSCMSSL WTAPLVMRRP TNLADRCGLF DSPSPCSSTS SCSTRAVKRA DRSHEESPRG TKRRKSSEAS PVKADVPEPT QLPHQSLSLT SFPKGTIENI FHSDPRDLIG DFSKGYLFHT VSGKHQDLKY ISPEIMASVL NGKFANLIKE FVIIDCRYPY EYEGGHIKGA VNLHMEEEVE EFLLKKPIVP ADGKRVIVVF HCEFSSERGP RMCRYVRERD RLGNEYPKLH YPELYVLKGG YKEFFLKCQS HCEPPSYRPM HHEDFKEDLK KFRTKSRTWA GEKSKREMYS RLKKL
 3D Structure    ModBase 3D Structure for P48965
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rat
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Cdc25a recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Cdc25a recombinant protein

   CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
NCBI/Uniprot data below describe general gene information for Cdc25a. It may not necessarily be applicable to this product.
 NCBI GI #    19424258
 NCBI GeneID    171102
 NCBI Accession #    NP_598255.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_133571.1 [Other Products]
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 UniProt Primary Accession #    P48965 [Other Products]
 UniProt Related Accession #    P48965 [Other Products]
 Molecular Weight    59,218 Da
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 NCBI Official Full Name    M-phase inducer phosphatase 1
 NCBI Official Synonym Full Names    cell division cycle 25A
 NCBI Official Symbol    Cdc25a [Similar Products]
 NCBI Protein Information    M-phase inducer phosphatase 1
 UniProt Protein Name    M-phase inducer phosphatase 1
 UniProt Synonym Protein Names   
Dual specificity phosphatase Cdc25A
 Protein Family    M-phase inducer phosphatase
 UniProt Gene Name    Cdc25a [Similar Products]
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 NCBI Summary for Cdc25a    novel phosphatase that mediates the start of the cell cycle; predominantly expressed in late G1, does not fucntion as mitotic regulator [RGD, Feb 2006]
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 UniProt Comments for Cdc25a    Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro (). Phosphorylation by PIM1 leads to an increase in phosphatase activity.
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 Research Articles on Cdc25a    1. accelerated cholangiocyte cystogenesis is likely due to overexpression of Cdc25A
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Cdc25a recombinant proteinPathways associated with Cdc25a recombinant protein
 Reference Product  PubMed Publications
 Cdk2 recombinant protein  >189 publications with Cdc25a and Cdk2
 Myc recombinant protein  >100 publications with Cdc25a and Myc
 Cdk1 recombinant protein  >67 publications with Cdc25a and Cdk1
 Cdk4 recombinant protein  >65 publications with Cdc25a and Cdk4
 Chek2 recombinant protein  >64 publications with Cdc25a and Chek2
 Ccnb1 recombinant protein  >39 publications with Cdc25a and Ccnb1
 Cdk6 recombinant protein  >31 publications with Cdc25a and Cdk6
 Wee1 recombinant protein  >19 publications with Cdc25a and Wee1
 Ccne1 recombinant protein  >7 publications with Cdc25a and Ccne1
 Chek1 recombinant protein  >3 publications with Cdc25a and Chek1
 Products by Pathway  Pathway Diagram
 Activation Of ATR In Response To Replication Stress Pathway antibodies  Activation Of ATR In Response To Replication Stress Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Checkpoints Pathway antibodies  Cell Cycle Checkpoints Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cyclin A/B1 Associated Events During G2/M Transition Pathway antibodies  Cyclin A/B1 Associated Events During G2/M Transition Pathway Diagram
 Cyclin A:Cdk2-associated Events At S Phase Entry Pathway antibodies  Cyclin A:Cdk2-associated Events At S Phase Entry Pathway Diagram
 Cyclin B2 Mediated Events Pathway antibodies  Cyclin B2 Mediated Events Pathway Diagram
Diseases associated with Cdc25a recombinant proteinOrgans/Tissues associated with Cdc25a recombinant protein
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >65 publications with Cdc25a and Breast Neoplasms
 Liver Diseases Antibodies  >39 publications with Cdc25a and Liver Diseases
 Liver Neoplasms Antibodies  >32 publications with Cdc25a and Liver Neoplasms
 Neoplasms, Experimental Antibodies  >30 publications with Cdc25a and Neoplasms, Experimental
 Carcinoma, Hepatocellular Antibodies  >30 publications with Cdc25a and Carcinoma, Hepatocellular
 Lung Neoplasms Antibodies  >29 publications with Cdc25a and Lung Neoplasms
 Lung Diseases Antibodies  >24 publications with Cdc25a and Lung Diseases
 Prostatic Neoplasms Antibodies  >19 publications with Cdc25a and Prostatic Neoplasms
 Necrosis Antibodies  >16 publications with Cdc25a and Necrosis
 Neoplasm Invasiveness Antibodies  >15 publications with Cdc25a and Neoplasm Invasiveness
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >55 publications with Cdc25a and Liver
 Prostate Antibodies  >29 publications with Cdc25a and Prostate
 Brain Antibodies  >17 publications with Cdc25a and Brain
 Embryonic Tissue Antibodies  >14 publications with Cdc25a and Embryonic Tissue
 Eye Antibodies  >7 publications with Cdc25a and Eye
 Heart Antibodies  >5 publications with Cdc25a and Heart
 Pancreas Antibodies  >2 publications with Cdc25a and Pancreas
 Small Intestine Antibodies  >2 publications with Cdc25a and Small Intestine
 Placenta Antibodies  >1 publications with Cdc25a and Placenta
 Uncharacterized Tissue Antibodies  >1 publications with Cdc25a and Uncharacterized Tissue
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