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MAPRE2 recombinant protein

Scan QR to view Datasheet Catalog #    MBS204315
SDS-Page
Unit / Price
0.1 mg  /  $310 +1 FREE 8GB USB
0.5 mg  /  $720 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MAPRE2, Recombinant Protein

 Also Known As   

MAPRE2, 1-327aa, Human, His tag, E Coli

 Product Synonym Names    Microtubule-associated protein RP/EB family member 2; Microtubule-associated protein; RP/EB family member 2; EB1; EB2; RP1
 Product Gene Name   

MAPRE2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHHHHH SSGLVPRGSH MPGPTQTLSP NGENNNDIIQ DNNGTIIPFR KHTVRGERSY SWGMAVNVYS TSITQETMSR HDIIAWVNDI VSLNYTKVEQ LCSGAAYCQF MDMLFPGCIS LKKVKFQAKL EHEYIHNFKL LQASFKRMNV DKVIPVEKLV KGRFQDNLDF IQWFKKFYDA NYDGKEYDPV EARQGQDAIP PPDPGEQIFN LPKKSHHANS PTAGAAKSSP AAKPGSTPSR PSSAKRASSS GSASKSDKDL ETQVIQLNEQ VHSLKLALEG VEKERDFYFG KLREIELLCQ EHGQENDDLV QRLMDILYAS EEHEGHTEEP EAEEQAHEQQ PPQQEEY
 OMIM    X94232 mRNA
 3D Structure    ModBase 3D Structure for Q15555
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 Host    E Coli
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 Purity/Purification    > 85% by SDS-PAGE
 Form/Format    Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
 Concentration    1 mg/ml (determined by Bradford assay) (lot specific)
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 Antigen Species    Human
 Tag Information    His-tag
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of MAPRE2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for MAPRE2 recombinant protein

   MAPRE2, also known as RP1 or EB2, is evolutionarily conserved proteins, which associate with the tips of growing microtubules, and regulate microtubule dynamics and their interactions with intracellular structures. It has been shown that EB proteins regulate microtubule function through CLIP proteins. Recombinant human MAPRE2 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography.
 Product Categories/Family for MAPRE2 recombinant protein    Cytoskeleton
 Applications Tested/Suitable for MAPRE2 recombinant protein   

SDS-PAGE

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 SDS-Page of MAPRE2 recombinant protein    MAPRE2 recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for MAPRE2. It may not necessarily be applicable to this product.
 NCBI GI #    10346135
 NCBI GeneID    10982
 NCBI Accession #    NP_055083 [Other Products]
 NCBI GenBank Nucleotide #    NM_014268.3 [Other Products]
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 UniProt Primary Accession #    Q15555 [Other Products]
 UniProt Secondary Accession #    Q9UQ33; B2RE21; B3KR39; B4DJV4; B7Z2L3; E9PHR3; F5H1V8; G5E9I6 [Other Products]
 UniProt Related Accession #    Q15555 [Other Products]
 Molecular Weight    39.2 kDa (347aa), confirmed by MALDI-TOF
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 NCBI Official Full Name    microtubule-associated protein RP/EB family member 2 isoform 1
 NCBI Official Synonym Full Names    microtubule associated protein RP/EB family member 2
 NCBI Official Symbol    MAPRE2 [Similar Products]
 NCBI Official Synonym Symbols   
EB1; EB2; RP1; CSCSC2
[Similar Products]
 NCBI Protein Information    microtubule-associated protein RP/EB family member 2
 UniProt Protein Name    Microtubule-associated protein RP/EB family member 2
 UniProt Synonym Protein Names   
APC-binding protein EB2; End-binding protein 2; EB2
 Protein Family    Microtubule-associated protein RP/EB family
 UniProt Gene Name    MAPRE2 [Similar Products]
 UniProt Synonym Gene Names    RP1; EB2 [Similar Products]
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 NCBI Summary for MAPRE2    The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
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 UniProt Comments for MAPRE2    May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration ().
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Product References and Citations for MAPRE2 recombinant protein

   Renner C., et al. (1997) J. Immunol. 159:1279-1283; Bu W., et al. (2003) J. Biol. Chem. 278:49721-49731
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 Research Articles on MAPRE2    1. Aurora B and CDK1 temporally regulate the binding affinity of EB2 for microtubules, thereby ensuring kinetochore microtubule dynamics, proper mitotic progression and genome stability.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MAPRE2 recombinant proteinDiseases associated with MAPRE2 recombinant protein
 Reference Product  PubMed Publications
 TUBB recombinant protein  >2 publications with MAPRE2 and TUBB
 CLASP2 recombinant protein  >1 publications with MAPRE2 and CLASP2
 AURKB recombinant protein  >1 publications with MAPRE2 and AURKB
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >2 publications with MAPRE2 and Congenital Abnormalities
 Abnormalities, Multiple Antibodies  >2 publications with MAPRE2 and Abnormalities, Multiple
 Lung Neoplasms Antibodies  >1 publications with MAPRE2 and Lung Neoplasms
 Brain Diseases Antibodies  >1 publications with MAPRE2 and Brain Diseases
 Poisoning Antibodies  >1 publications with MAPRE2 and Poisoning
 Neoplasm Invasiveness Antibodies  >1 publications with MAPRE2 and Neoplasm Invasiveness
 Abnormalities, Drug-Induced Antibodies  >1 publications with MAPRE2 and Abnormalities, Drug-Induced
Organs/Tissues associated with MAPRE2 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3 publications with MAPRE2 and Blood
 Eye Antibodies  >2 publications with MAPRE2 and Eye
 Skin Antibodies  >2 publications with MAPRE2 and Skin
 Brain Antibodies  >2 publications with MAPRE2 and Brain
 Ganglia Antibodies  >1 publications with MAPRE2 and Ganglia
 Lung Antibodies  >1 publications with MAPRE2 and Lung
 Intestine Antibodies  >1 publications with MAPRE2 and Intestine
 Nerve Antibodies  >1 publications with MAPRE2 and Nerve
 Kidney Antibodies  >1 publications with MAPRE2 and Kidney
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