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MCP3 recombinant protein

Scan QR to view Datasheet Catalog #    MBS539544 MCP3 recombinant protein
Unit / Price
0.01 mg  /  $310 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MCP3, Recombinant Protein

 Also Known As   

MCP3 protein (Mouse)

 Product Synonym Names    MCP-3 protein; MARC protein; MCP 3 protein; MCP3; Monocyte Chemotactic Protein-3 protein; MCP-3; CCL7 protein; MCP 3
 Product Gene Name   

MCP3 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    Region of MCP3 protein correspond ing to amino acids QPDGPNASTC CYVKKQKIPK RNLKSYRRIT SSRCPWEAVI FKTKKGMEVC AEAHQKWVEE AIAYLDMKTP TPKP.
 OMIM    158106
 3D Structure    ModBase 3D Structure for P80098
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 Host    Mouse
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 Purity/Purification    > 98% pure
 Form/Format    Supplied as a lyophilized powder.
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 Protein Type    Recombinant
 Biological Significance    The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species.
 Bioactivity    Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 10.0-100.0 ng/ml.
 Endotoxin Levels    Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
 Expression System    E Coli
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 Preparation and Storage    Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of MCP3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for MCP3 recombinant protein

   Purified recombinant Mouse MCP3 protein
 Product Categories/Family for MCP3 recombinant protein    Cytokines & Growth Factors
 Applications Tested/Suitable for MCP3 recombinant protein   

User optimized

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NCBI/Uniprot data below describe general gene information for MCP3. It may not necessarily be applicable to this product.
 NCBI GI #    313708
 NCBI Accession #    CAA51055.1 [Other Products]
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 UniProt Primary Accession #    P80098 [Other Products]
 UniProt Secondary Accession #    Q569J6 [Other Products]
 Molecular Weight    8.5 kDa
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 NCBI Official Full Name    monocyte chemotactic protein-3
 UniProt Protein Name    C-C motif chemokine 7
 UniProt Synonym Protein Names   
Monocyte chemoattractant protein 3; Monocyte chemotactic protein 3; MCP-3; NC28; Small-inducible cytokine A7
 Protein Family    Meiotic coiled-coil protein
 UniProt Gene Name    CCL7 [Similar Products]
 UniProt Synonym Gene Names    MCP3; SCYA6; SCYA7; MCP-3 [Similar Products]
 UniProt Entry Name    CCL7_HUMAN
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 UniProt Comments for MCP3    CCL7: Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 17q11.2-q12

Cellular Component: extracellular space; extracellular region

Molecular Function: heparin binding; CCR1 chemokine receptor binding; chemokine activity; CCR2 chemokine receptor binding

Biological Process: cellular calcium ion homeostasis; regulation of cell shape; monocyte chemotaxis; cell-cell signaling; eosinophil chemotaxis; response to gamma radiation; immune response; cytoskeleton organization and biogenesis; inflammatory response; chemotaxis; signal transduction; positive regulation of cell migration
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MCP3 recombinant proteinDiseases associated with MCP3 recombinant protein
 Reference Product  PubMed Publications
 CCL2 recombinant protein  >271 publications with MCP3 and CCL2
 CCR2 recombinant protein  >93 publications with MCP3 and CCR2
 CCL4 recombinant protein  >79 publications with MCP3 and CCL4
 CCL3 recombinant protein  >76 publications with MCP3 and CCL3
 CCR1 recombinant protein  >45 publications with MCP3 and CCR1
 CCR3 recombinant protein  >44 publications with MCP3 and CCR3
 CCR5 recombinant protein  >37 publications with MCP3 and CCR5
 CXCR3 recombinant protein  >10 publications with MCP3 and CXCR3
 CCR10 recombinant protein  >3 publications with MCP3 and CCR10
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >201 publications with MCP3 and Inflammation
 Lung Diseases Antibodies  >58 publications with MCP3 and Lung Diseases
 Necrosis Antibodies  >54 publications with MCP3 and Necrosis
 Hypersensitivity Antibodies  >53 publications with MCP3 and Hypersensitivity
 Disease Models, Animal Antibodies  >51 publications with MCP3 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >26 publications with MCP3 and Cardiovascular Diseases
 Fibrosis Antibodies  >23 publications with MCP3 and Fibrosis
 Atherosclerosis Antibodies  >15 publications with MCP3 and Atherosclerosis
 Heart Diseases Antibodies  >13 publications with MCP3 and Heart Diseases
 Liver Diseases Antibodies  >10 publications with MCP3 and Liver Diseases
Organs/Tissues associated with MCP3 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >284 publications with MCP3 and Blood
 Lung Antibodies  >73 publications with MCP3 and Lung
 Skin Antibodies  >37 publications with MCP3 and Skin
 Intestine Antibodies  >14 publications with MCP3 and Intestine
 Uterus Antibodies  >10 publications with MCP3 and Uterus
 Placenta Antibodies  >4 publications with MCP3 and Placenta
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