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rmMIG recombinant protein :: MIG Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS142044 rmMIG recombinant protein
Unit / Price
0.005 mg  /  $140 +1 FREE 8GB USB
0.02 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $2,665 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MIG (rmMIG), Recombinant Protein

 Also Known As   

Recombinant Mouse MIG (CXCL9)

 Product Synonym Names    MIG Mouse; MIG Mouse Recombinant (CXCL9); Small inducible cytokine B9; CXCL9; Gamma interferon-induced monokine; MIG; chemokine (C-X-C motif) ligand 9; CMK; Humig; SCYB9; crg-10; M119; monokine induced by gamma-interferon
 Product Gene Name   

rmMIG recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    The sequence of the first five N-terminal amino acids was determined and was found to be, Thr-Leu-Va l-Ile-Arg
 3D Structure    ModBase 3D Structure for P18340
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 Host    E Coli
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 Purity/Purification    Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
 Form/Format    The CXCL9 was lyophilized from a concentrated (1mg/ml) solution in water containing no additives.
Sterile Filtered White lyophilized (freeze-dried) powder.
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 Solubility    It is recommended to reconstitute the lyophilized MIG in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
 Biological Activity    The Activity is calculated by the ability to chemoattract Human lymphocytes using a concentration of 0.1-1ng/ml corresponding to a Specific Activity of 1,000,000-10,000,000IU/mg.
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 Preparation and Storage    Lyophilized MIG although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution CXCL9 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
 Other Notes    Small volumes of rmMIG recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for rmMIG recombinant protein

   Description: MIG (monokine induced by gamma-interferon) Mouse Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 105 amino acids and having a molecular mass of 12208 Dalton. The MIG is purified by proprietary chromatographic techniques.

Introduction: Chemokine (C-X-C motif) ligand 9 (CXCL9) is a small cytokine belonging to the CXC chemokine family that is also known as Monokine induced by gamma interferon (MIG). CXCL9 is a T-cell chemoattractant, which is induced by IFN-?. It is closely related to two other CXC chemokines called CXCL10 and CXCL11, whose genes are located near the gene for CXCL9 on human chromosome 4. CXCL9, CXCL10 and CXCL11 all elicit their chemotactic functions by interacting with the chemokine receptor CXCR3.
 Product Categories/Family for rmMIG recombinant protein    CHEMOKINES; Chemokines; MIG (CXCL9)
NCBI/Uniprot data below describe general gene information for rmMIG. It may not necessarily be applicable to this product.
 NCBI GI #    110626107
 NCBI GeneID    17329
 NCBI Accession #    NP_032625.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_008599.4 [Other Products]
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 UniProt Primary Accession #    P18340 [Other Products]
 UniProt Secondary Accession #    Q8C9J0; Q99J60 [Other Products]
 UniProt Related Accession #    P18340 [Other Products]
 Molecular Weight    14,444 Da
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 NCBI Official Full Name    C-X-C motif chemokine 9
 NCBI Official Synonym Full Names    chemokine (C-X-C motif) ligand 9
 NCBI Official Symbol    Cxcl9 [Similar Products]
 NCBI Official Synonym Symbols   
CMK; Mig; MuMIG; Scyb9; crg-10; BB139920
[Similar Products]
 NCBI Protein Information    C-X-C motif chemokine 9; M119; gamma interferon-induced monokine; gamma-interferon-induced monokine; monokine induced by gamma interferon; monokine induced by interferon-gamma; protein m119; small inducible cytokine B subfamily (Cys-X-Cys), member 9; small-inducible cytokine B9
 UniProt Protein Name    C-X-C motif chemokine 9
 UniProt Synonym Protein Names   
Gamma-interferon-induced monokine; Monokine induced by interferon-gamma; MIG; MuMIG; Protein m119; Small-inducible cytokine B9
 Protein Family    Migration and invasion enhancer
 UniProt Gene Name    Cxcl9 [Similar Products]
 UniProt Synonym Gene Names    Mig; Scyb9; MIG; MuMIG [Similar Products]
 UniProt Entry Name    CXCL9_MOUSE
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 UniProt Comments for rmMIG    CXCL9: Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Cellular Component: extracellular space; extracellular region; external side of plasma membrane

Molecular Function: CXCR3 chemokine receptor binding; chemokine activity; cytokine activity

Biological Process: G-protein coupled receptor protein signaling pathway; response to lipopolysaccharide; positive regulation of leukocyte chemotaxis; immune response; chemotaxis; inflammatory response; defense response to virus; positive regulation of myoblast differentiation; regulation of cell proliferation
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 Research Articles on rmMIG    1. In our mouse model, fatal progression of AIH is mediated by IL-18-dependent differentiation of T cells into Th1 cells and effector T cells, respectively, and that CXCR3-CXCL9 axis-dependent migration of those T cells is crucial for fatal progression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with rmMIG recombinant proteinDiseases associated with rmMIG recombinant protein
 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >412 publications with rmMIG and Inflammation
 Necrosis Antibodies  >213 publications with rmMIG and Necrosis
 Disease Models, Animal Antibodies  >156 publications with rmMIG and Disease Models, Animal
 Lung Diseases Antibodies  >118 publications with rmMIG and Lung Diseases
 Liver Diseases Antibodies  >85 publications with rmMIG and Liver Diseases
 Carcinoma Antibodies  >73 publications with rmMIG and Carcinoma
 Cardiovascular Diseases Antibodies  >59 publications with rmMIG and Cardiovascular Diseases
 Hypersensitivity Antibodies  >57 publications with rmMIG and Hypersensitivity
 Fibrosis Antibodies  >57 publications with rmMIG and Fibrosis
 Neoplasms, Experimental Antibodies  >55 publications with rmMIG and Neoplasms, Experimental
Organs/Tissues associated with rmMIG recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >170 publications with rmMIG and Lung
 Liver Antibodies  >121 publications with rmMIG and Liver
 Lymph Node Antibodies  >92 publications with rmMIG and Lymph Node
 Spleen Antibodies  >80 publications with rmMIG and Spleen
 Kidney Antibodies  >72 publications with rmMIG and Kidney
 Bone Antibodies  >60 publications with rmMIG and Bone
 Thymus Antibodies  >20 publications with rmMIG and Thymus
 Mammary Gland Antibodies  >4 publications with rmMIG and Mammary Gland
 Adipose Tissue Antibodies  >3 publications with rmMIG and Adipose Tissue
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