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MIP1 beta recombinant protein

Scan QR to view Datasheet Catalog #    MBS539404 MIP1 beta recombinant protein
Unit / Price
0.01 mg  /  $310 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MIP1 beta, Recombinant Protein

 Also Known As   

MIP1 beta protein (Mouse)

 Product Synonym Names    MIP beta 1 protein; MIP beta-1 protein; MIP1 beta; MIP beta-1; ACT-2 protein; MIP-1 beta protein; CCL4 protein; Macrophage Inflammatory Protein-1 beta protein; MIP beta 1
 Product Gene Name   

MIP1 beta recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    Region of MIP1 beta protein correspond ing to amino acids APMGSDPPTS CCFSYTSRQL HRSFVMDYYE TSSLCSKPAV VFLTKRGRQI CANPSEPWVT EYMSDLELN.
 3D Structure    ModBase 3D Structure for P50230
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 Host    Mouse
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 Purity/Purification    > 95% pure
 Form/Format    Supplied as a lyophilized powder.
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 Protein Type    Recombinant
 Biological Significance    Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and Mouse MIP-1 alpha and MIP-1 beta are active on human and Mouse hematopoietic cells.
 Bioactivity    Determined by its ability to chemoattract human monocytes using a concentration range of 20.0-100.0 ng/ml.
 Endotoxin Levels    Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
 Expression System    E Coli
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 Preparation and Storage    Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of MIP1 beta recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for MIP1 beta recombinant protein

   Purified recombinant Mouse MIP1 beta protein
 Product Categories/Family for MIP1 beta recombinant protein    Cytokines & Growth Factors
 Applications Tested/Suitable for MIP1 beta recombinant protein   

User optimized

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NCBI/Uniprot data below describe general gene information for MIP1 beta. It may not necessarily be applicable to this product.
 NCBI GI #    459148
 NCBI GeneID    116637
 NCBI Accession #    AAA96497.1 [Other Products]
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 UniProt Primary Accession #    P50230 [Other Products]
 UniProt Secondary Accession #    A1EC89 [Other Products]
 UniProt Related Accession #    P50230 [Other Products]
 Molecular Weight    7.8 kDa
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 NCBI Official Full Name    macrophage inflammatory protein-1 beta
 NCBI Official Synonym Full Names    chemokine (C-C motif) ligand 4
 NCBI Official Symbol    Ccl4 [Similar Products]
 NCBI Official Synonym Symbols   
Scya4; Mip1-b
[Similar Products]
 NCBI Protein Information    C-C motif chemokine 4
 UniProt Protein Name    C-C motif chemokine 4
 UniProt Synonym Protein Names   
Macrophage inflammatory protein 1-beta; MIP-1-beta; Small-inducible cytokine A4
 UniProt Gene Name    Ccl4 [Similar Products]
 UniProt Synonym Gene Names    Mip1b; Scya4; MIP-1-beta [Similar Products]
 UniProt Entry Name    CCL4_RAT
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 NCBI Summary for MIP1 beta    a cytokine that is up-regulated during the inflammatory response; may be involved in intrapulmonary recruitment of neutrophils [RGD, Feb 2006]
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 UniProt Comments for MIP1 beta    Monokine with inflammatory and chemokinetic properties.
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 Research Articles on MIP1 beta    1. Tong Luo Jiu Nao injection inhibits MIP-1beta expression in brain microvascular endothelial cells injured by oxygen-glucose deprivation and inhibitors microglial cell proliferation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MIP1 beta recombinant proteinPathways associated with MIP1 beta recombinant protein
 Reference Product  PubMed Publications
 Ccl3 recombinant protein  >1641 publications with MIP1 beta and Ccl3
 Ccl5 recombinant protein  >1009 publications with MIP1 beta and Ccl5
 Ccl2 recombinant protein  >836 publications with MIP1 beta and Ccl2
 Ccr5 recombinant protein  >602 publications with MIP1 beta and Ccr5
 Ccr1 recombinant protein  >200 publications with MIP1 beta and Ccr1
 Cxcr3 recombinant protein  >76 publications with MIP1 beta and Cxcr3
 Ccr7 recombinant protein  >53 publications with MIP1 beta and Ccr7
 Cxcr2 recombinant protein  >27 publications with MIP1 beta and Cxcr2
 Ccr9 recombinant protein  >9 publications with MIP1 beta and Ccr9
 Ccbp2 recombinant protein  >1 publications with MIP1 beta and Ccbp2
 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 NF-kappa B Signaling Pathway antibodies  NF-kappa B Signaling Pathway Diagram
Diseases associated with MIP1 beta recombinant proteinOrgans/Tissues associated with MIP1 beta recombinant protein
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >2776 publications with MIP1 beta and Liver Diseases
 Poisoning Antibodies  >2056 publications with MIP1 beta and Poisoning
 Drug-Induced Liver Injury Antibodies  >1668 publications with MIP1 beta and Drug-Induced Liver Injury
 Disease Models, Animal Antibodies  >1326 publications with MIP1 beta and Disease Models, Animal
 Necrosis Antibodies  >1252 publications with MIP1 beta and Necrosis
 Drug-Related Side Effects and Adverse Reactions Antibodies  >1241 publications with MIP1 beta and Drug-Related Side Effects and Adverse Reactions
 Inflammation Antibodies  >1151 publications with MIP1 beta and Inflammation
 Fibrosis Antibodies  >1018 publications with MIP1 beta and Fibrosis
 Fatty Liver Antibodies  >297 publications with MIP1 beta and Fatty Liver
 Lung Diseases Antibodies  >263 publications with MIP1 beta and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >167 publications with MIP1 beta and Mixed
 Eye Antibodies  >67 publications with MIP1 beta and Eye
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