View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List MIP1 beta active protein Catalog # MBS539404 Unit / Price 0.01 mg / $475 +1 FREE 8GB USB 5x0.01 mg / $1,955 +2 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name MIP1 beta, Active Protein Full Product Name MIP1 beta protein (Mouse) Product Synonym Names MIP beta 1 protein; MIP beta-1 protein; MIP1 beta; MIP beta-1; ACT-2 protein; MIP-1 beta protein; CCL4 protein; Macrophage Inflammatory Protein-1 beta protein; MIP beta 1 Product Gene Name MIP1 beta active protein[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence Region of MIP1 beta protein correspond ing to amino acids APMGSDPPTS CCFSYTSRQL HRSFVMDYYE TSSLCSKPAV VFLTKRGRQI CANPSEPWVT EYMSDLELN. 3D Structure ModBase 3D Structure for P50230 Host Mouse Purity/Purification > 95% pure Form/Format Supplied as a lyophilized powder. Protein Type Recombinant Biological Significance Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and Mouse MIP-1 alpha and MIP-1 beta are active on human and Mouse hematopoietic cells. Bioactivity Determined by its ability to chemoattract human monocytes using a concentration range of 20.0-100.0 ng/ml. Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug). Expression System E Coli Preparation and Storage Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles. Active Protein Note Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product. Other Notes Small volumes of MIP1 beta active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for MIP1 beta active protein Purified recombinant Mouse MIP1 beta protein Product Categories/Family for MIP1 beta active protein Cytokines & Growth Factors Applications Tested/Suitable for MIP1 beta active protein User optimized TOP NCBI/Uniprot data below describe general gene information for MIP1 beta. It may not necessarily be applicable to this product. NCBI GI # 459148 NCBI GeneID 116637 NCBI Accession # AAA96497.1 [Other Products] UniProt Primary Accession # P50230 [Other Products] UniProt Secondary Accession # A1EC89[Other Products] UniProt Related Accession # P50230[Other Products] Molecular Weight 7.8 kDa TOP NCBI Official Full Name macrophage inflammatory protein-1 beta NCBI Official Synonym Full Names chemokine (C-C motif) ligand 4 NCBI Official Symbol Ccl4 [Similar Products] NCBI Official Synonym Symbols Scya4; Mip1-b [Similar Products] NCBI Protein Information C-C motif chemokine 4 UniProt Protein Name C-C motif chemokine 4 UniProt Synonym Protein Names Macrophage inflammatory protein 1-beta; MIP-1-beta; Small-inducible cytokine A4 UniProt Gene Name Ccl4 [Similar Products] UniProt Synonym Gene Names Mip1b; Scya4; MIP-1-beta [Similar Products] UniProt Entry Name CCL4_RAT TOP NCBI Summary for MIP1 beta a cytokine that is up-regulated during the inflammatory response; may be involved in intrapulmonary recruitment of neutrophils [RGD, Feb 2006] TOP UniProt Comments for MIP1 beta Monokine with inflammatory and chemokinetic properties. Research Articles on MIP1 beta 1. Tong Luo Jiu Nao injection inhibits MIP-1beta expression in brain microvascular endothelial cells injured by oxygen-glucose deprivation and inhibitors microglial cell proliferation. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with MIP1 beta active protein Reference Product PubMed Publications Ccl3 active protein >1641 publications with MIP1 beta and Ccl3 Ccl5 active protein >1009 publications with MIP1 beta and Ccl5 Ccl2 active protein >836 publications with MIP1 beta and Ccl2 Ccr5 active protein >602 publications with MIP1 beta and Ccr5 Ccr1 active protein >200 publications with MIP1 beta and Ccr1 Cxcr3 active protein >76 publications with MIP1 beta and Cxcr3 Ccr7 active protein >53 publications with MIP1 beta and Ccr7 Cxcr2 active protein >27 publications with MIP1 beta and Cxcr2 Ccr9 active protein >9 publications with MIP1 beta and Ccr9 Ccbp2 active protein >1 publications with MIP1 beta and Ccbp2 Pathways associated with MIP1 beta active protein Products by Pathway Pathway Diagram Chemokine Receptors Bind Chemokines Pathway antibodies Chemokine Receptors Bind Chemokines Pathway Diagram Chemokine Signaling Pathway antibodies Chemokine Signaling Pathway Diagram Chemokine Signaling Pathway antibodies Chemokine Signaling Pathway Diagram Class A/1 (Rhodopsin-like Receptors) Pathway antibodies Class A/1 (Rhodopsin-like Receptors) Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram Cytosolic DNA-sensing Pathway antibodies Cytosolic DNA-sensing Pathway Diagram Cytosolic DNA-sensing Pathway antibodies Cytosolic DNA-sensing Pathway Diagram GPCR Ligand Binding Pathway antibodies GPCR Ligand Binding Pathway Diagram NF-kappa B Signaling Pathway antibodies NF-kappa B Signaling Pathway Diagram Diseases associated with MIP1 beta active protein Disease Name Pubmed Publications Liver Diseases Antibodies >2776 publications with MIP1 beta and Liver Diseases Poisoning Antibodies >2056 publications with MIP1 beta and Poisoning Drug-Induced Liver Injury Antibodies >1668 publications with MIP1 beta and Drug-Induced Liver Injury Disease Models, Animal Antibodies >1326 publications with MIP1 beta and Disease Models, Animal Necrosis Antibodies >1252 publications with MIP1 beta and Necrosis Drug-Related Side Effects and Adverse Reactions Antibodies >1241 publications with MIP1 beta and Drug-Related Side Effects and Adverse Reactions Inflammation Antibodies >1151 publications with MIP1 beta and Inflammation Fibrosis Antibodies >1018 publications with MIP1 beta and Fibrosis Fatty Liver Antibodies >297 publications with MIP1 beta and Fatty Liver Lung Diseases Antibodies >263 publications with MIP1 beta and Lung Diseases Organs/Tissues associated with MIP1 beta active protein Organ/Tissue Name Pubmed Publications Mixed Antibodies >167 publications with MIP1 beta and Mixed Eye Antibodies >67 publications with MIP1 beta and Eye TOP © 2006-24 MyBioSource.com. All rights reserved. Privacy Policy | Terms & Conditions Our Best Sellers BACH1 Blocking Peptide IPO7 Antibody alpha Defensin-4 (NP-4) (DEFA4) ELISA Kit AFF2 Antibody F box-WD repeat containing protein 11 (FBXW11) ELISA Kit IL-12 ELISA Kit IL-1beta ELISA Kit N-Acetyl Beta-D-Glucosaminidase (NAGase) Antibody ELISA Antibodies Secondary Antibodies Antigens Biochemicals cDNA Clones Kits Peptides Rec Proteins Protein Family Request a Quote Please fill out the form below and our representative will get back to you shortly. Catalog # MBS000000 Your E-mail (required) Ship to Country (required) United StatesAfghanistanAlbaniaAlgeriaAmerican SamoaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBoliviaBosnia and HerzegowinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCook IslandsCosta RicaCote DIvoireCroatiaCubaCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEast TimorEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrance MetropolitanFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuamGuatemalaGuineaGuinea-bissauGuyanaHaitiHeard and Mc Donald IslandsHondurasHong KongHungaryIcelandIndiaIndonesiaIran (Islamic Republic of)IraqIrelandIsraelItalyJamaicaJapanJordanKazakhstanKenyaKiribatiKorea Democratic People Republic ofKorea Republic ofKuwaitKyrgyzstanLao People Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacauMacedonia The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMarshall IslandsMartiniqueMauritaniaMauritiusMayotteMexicoMicronesia Federated States ofMoldova Republic ofMonacoMongoliaMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNetherlands AntillesNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorthern Mariana IslandsNorwayOmanPakistanPalauPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalPuerto RicoQatarReunionRomaniaRussian FederationRwandaSaint Kitts and NevisSaint LuciaSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSeychellesSierra LeoneSingaporeSlovakia (Slovak Republic)SloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSpainSri LankaSt. HelenaSt. Pierre and MiquelonSudanSurinameSvalbard and Jan Mayen IslandsSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania United Republic ofThailandTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUnited States Minor Outlying IslandsUruguayUzbekistanVanuatuVatican City State (Holy See)VenezuelaViet NamVirgin Islands (British)Virgin Islands (U.S.)Wallis and Futuna IslandsWestern SaharaYemenYugoslaviaZaireZambiaZimbabwe Postal/Zip Code (required) Your Name Your Telephone Your Inquiries, Comments or Full Shipping Address (required) Contact Us Please fill out the form below and our representative will get back to you shortly. Inquiry for # MBS000000 Your Name Your Telephone Your E-mail (required) Your Inquiries or Comments