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MORC3 recombinant protein :: MORC family CW-type zinc finger protein 3 (MORC3), partial Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1330158
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Unit / Price
0.05 mg (E-Coli)  /  $695 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $935 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,025 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,450 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MORC family CW-type zinc finger protein 3 (MORC3), partial, Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human MORC family CW-type zinc finger protein 3 (MORC3), partial

 Product Synonym Names    MORC family CW-type zinc finger protein 3; Zinc finger CW-type coiled-coil domain protein 3
 Product Gene Name   

MORC3 recombinant protein

[Similar Products]
 Product Synonym Gene Name    MORC3; KIAA0136; ZCWCC3 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS1330158 COA    COA PDF
 Sequence Positions    1-290aa; Partial
 Sequence    MAAQPPRGIR LSALCPKFLH TNSTSHTWPF SAVAELIDNA YDPDVNAKQI WIDKTVINDH ICLTFTDNGN GMTSDKLHKM LSFGFSDKVT MNGHVPVGLY GNGFKSGSMR LGKDAIVFTK NGESMSVGLL SQTYLEVIKA EHVVVPIVAF NKHRQMINLA ESKASLAAIL EHSLFSTEQK LLAELDAIIG KKGTRIIIWN LRSYKNATEF DFEKDKYDIR IPEDLDEITG KKGYKKQERM DQIAPESDYS LRAYCSILYL KPRMQIILRG QKVKTQLVSK SLAYIERDVY
 OMIM    610078
 3D Structure    ModBase 3D Structure for Q14149
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
 Production Note    Special Offer: The E. coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E. coli host-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E. coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E. coli host-expressed protein for the fastest delivery among all hosts. Please contact us or email to support@mybiosource.com for more details.
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of MORC3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for MORC3 recombinant protein

   Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism (PubMed:20501696). Sumoylated MORC3-NBs can also associate with PML-NBs (PubMed:20501696). Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity (PubMed:17332504). Binds RNA in vitro (PubMed:11927593). May be required for influenza A transcription during viral infection (PubMed:26202233).
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 SDS-Page of MORC3 recombinant protein    MORC3 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for MORC3. It may not necessarily be applicable to this product.
 NCBI GI #    28872812
 NCBI GeneID    23515
 NCBI Accession #    NP_056173.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_015358.2 [Other Products]
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 UniProt Primary Accession #    Q14149 [Other Products]
 UniProt Secondary Accession #    Q9UEZ2; A8KA92 [Other Products]
 UniProt Related Accession #    Q14149 [Other Products]
 Molecular Weight    107,113 Da
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 NCBI Official Full Name    MORC family CW-type zinc finger protein 3
 NCBI Official Synonym Full Names    MORC family CW-type zinc finger 3
 NCBI Official Symbol    MORC3 [Similar Products]
 NCBI Official Synonym Symbols   
NXP2; ZCW5; ZCWCC3
[Similar Products]
 NCBI Protein Information    MORC family CW-type zinc finger protein 3; nuclear matrix protein NXP2; zinc finger, CW type with coiled-coil domain 3; zinc finger, CW-type with coiled-coil domain 3; zinc finger CW-type coiled-coil domain protein 3
 UniProt Protein Name    MORC family CW-type zinc finger protein 3
 UniProt Synonym Protein Names   
Zinc finger CW-type coiled-coil domain protein 3
 Protein Family    MORC family CW-type zinc finger protein
 UniProt Gene Name    MORC3 [Similar Products]
 UniProt Synonym Gene Names    KIAA0136; ZCWCC3 [Similar Products]
 UniProt Entry Name    MORC3_HUMAN
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 NCBI Summary for MORC3    This gene encodes a protein that localizes to the nuclear matrix. The protein also has RNA binding activity, and has a predicted coiled-coil domain. [provided by RefSeq, Jul 2008]
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 UniProt Comments for MORC3    MORC3:

Protein type: Cell cycle regulation; RNA-binding

Chromosomal Location of Human Ortholog: 21q22.13

Cellular Component: nucleoplasm; intermediate filament cytoskeleton; PML body

Molecular Function: zinc ion binding

Biological Process: peptidyl-serine phosphorylation; protein stabilization; negative regulation of fibroblast proliferation; cell aging; maintenance of protein localization in nucleus; protein amino acid phosphorylation; post-embryonic development
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 Research Articles on MORC3    1. These studies demonstrate that anti-NXP-2 and anti-TIF-1gamma antibodies are frequent DM specificities (found in 55% of patients) and are present in most patients with cancer-associated dermatomhyositis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with MORC3 recombinant proteinOrgans/Tissues associated with MORC3 recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >10 publications with MORC3 and Nervous System Diseases
 Musculoskeletal Diseases Antibodies  >9 publications with MORC3 and Musculoskeletal Diseases
 Fibrosis Antibodies  >1 publications with MORC3 and Fibrosis
 Heart Defects, Congenital Antibodies  >1 publications with MORC3 and Heart Defects, Congenital
 Necrosis Antibodies  >1 publications with MORC3 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >8 publications with MORC3 and Blood
 Lung Antibodies  >3 publications with MORC3 and Lung
 Heart Antibodies  >2 publications with MORC3 and Heart
 Muscle Antibodies  >2 publications with MORC3 and Muscle
 Skin Antibodies  >1 publications with MORC3 and Skin
 Brain Antibodies  >1 publications with MORC3 and Brain
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