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MYL6 recombinant protein

Scan QR to view Datasheet Catalog #    MBS203807
SDS-PAGE
Unit / Price
0.05 mg  /  $375 +1 FREE 8GB USB
0.25 mg  /  $925 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MYL6, Recombinant Protein

 Also Known As   

MYL6, 1-151aa, Human, His tag, E Coli

 Product Synonym Names    Myosin light polypeptide 6; ESMLC; LC17-GI; LC17-NM; LC17A; LC17B; MLC1SM; MLC3NM; MLC3SM
 Product Gene Name   

MYL6 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHHHHH SSGLVPRGSH MCDFTEDQTA EFKEAFQLFD RTGDGKILYS QCGDVMRALG QNPTNAEVLK VLGNPKSDEM NVKVLDFEHF LPMLQTVAKN KDQGTYEDYV EGLRVFDKEG NGTVMGAEIR HVLVTLGEKM TEEEVEMLVA GHEDSNGCIN YEELVRMVLN G
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 Purity/Purification    > 90% by SDS - PAGE
 Form/Format    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
 Concentration    0.5 mg/ml (determined by Bradford assay) (lot specific)
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 Antigen Species    Human
 Tag    His-tag
 Expression System    E Coli
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of MYL6 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for MYL6 recombinant protein

   Myosin light polypeptide 6 is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. MYL6 participates in generating the force for cellular movements, thereby playing an important role in overall cellular function. Recombinant human MYL6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
 Product Categories/Family for MYL6 recombinant protein    Cytoskeleton
 Applications Tested/Suitable for MYL6 recombinant protein   

SDS-PAGE

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 SDS-PAGE of MYL6 recombinant protein    MYL6 recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for MYL6. It may not necessarily be applicable to this product.
 NCBI GI #    88999583
 NCBI GeneID    4637
 NCBI Accession #    NP_524147 [Other Products]
 NCBI GenBank Nucleotide #    NM_079423.3 [Other Products]
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 UniProt Secondary Accession #    P16475; P24572; P24573; Q12790; Q561V9; Q6IAZ0; Q6IPY5 [Other Products]
 UniProt Related Accession #    P60660 [Other Products]
 Molecular Weight    19.1 kDa (171aa) confirmed by MALDI-TOF
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 NCBI Official Full Name    myosin light polypeptide 6 isoform 2
 NCBI Official Synonym Full Names    myosin, light chain 6, alkali, smooth muscle and non-muscle
 NCBI Official Symbol    MYL6 [Similar Products]
 NCBI Official Synonym Symbols   
LC17; ESMLC; LC17A; LC17B; MLC-3; MLC1SM; MLC3NM; MLC3SM; LC17-GI; LC17-NM
[Similar Products]
 NCBI Protein Information    myosin light polypeptide 6; 17 kDa myosin light chain; myosin light chain A3; myosin light chain alkali 3; myosin, light polypeptide 6, alkali, smooth muscle and non-muscle
 UniProt Protein Name    Myosin light polypeptide 6
 UniProt Synonym Protein Names   
17 kDa myosin light chain; LC17; Myosin light chain 3; MLC-3; Myosin light chain alkali 3; Myosin light chain A3; Smooth muscle and nonmuscle myosin light chain alkali 6
 Protein Family    Myosin light polypeptide
 UniProt Gene Name    MYL6 [Similar Products]
 UniProt Synonym Gene Names    LC17; MLC-3; Myosin light chain A3 [Similar Products]
 UniProt Entry Name    MYL6_HUMAN
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 NCBI Summary for MYL6    Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for MYL6    MYL6: Regulatory light chain of myosin. Does not bind calcium. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Motor

Chromosomal Location of Human Ortholog: 12q13.2

Cellular Component: membrane; unconventional myosin complex; cytosol; myosin complex; vesicle

Molecular Function: protein binding; structural constituent of muscle; motor activity; calcium ion binding; actin-dependent ATPase activity

Biological Process: axon guidance; skeletal muscle development; muscle contraction; metabolic process; ephrin receptor signaling pathway; muscle filament sliding
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Product References and Citations for MYL6 recombinant protein

   Lenz S., et al. (1989) J Biol Chem. 264:9009-9015.
Komiyama M., et al. (1996) J Cell Sci. 109:2089-2099.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MYL6 recombinant proteinPathways associated with MYL6 recombinant protein
 Reference Product  PubMed Publications
 MYH10 recombinant protein  >1 publications with MYL6 and MYH10
 MYH9 recombinant protein  >1 publications with MYL6 and MYH9
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 EPH-Ephrin Signaling Pathway antibodies  EPH-Ephrin Signaling Pathway Diagram
 EPHA-mediated Growth Cone Collapse Pathway antibodies  EPHA-mediated Growth Cone Collapse Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Muscle Contraction Pathway antibodies  Muscle Contraction Pathway Diagram
 Oxytocin Signaling Pathway antibodies  Oxytocin Signaling Pathway Diagram
 Oxytocin Signaling Pathway antibodies  Oxytocin Signaling Pathway Diagram
 Sema4D In Semaphorin Signaling Pathway antibodies  Sema4D In Semaphorin Signaling Pathway Diagram
 Sema4D Induced Cell Migration And Growth-cone Collapse Pathway antibodies  Sema4D Induced Cell Migration And Growth-cone Collapse Pathway Diagram
Diseases associated with MYL6 recombinant proteinOrgans/Tissues associated with MYL6 recombinant protein
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >2 publications with MYL6 and Liver Diseases
 Inflammation Antibodies  >1 publications with MYL6 and Inflammation
 Liver Neoplasms Antibodies  >1 publications with MYL6 and Liver Neoplasms
 Disease Models, Animal Antibodies  >1 publications with MYL6 and Disease Models, Animal
 Breast Neoplasms Antibodies  >1 publications with MYL6 and Breast Neoplasms
 Carcinoma, Hepatocellular Antibodies  >1 publications with MYL6 and Carcinoma, Hepatocellular
 Drug-Related Side Effects and Adverse Reactions Antibodies  >1 publications with MYL6 and Drug-Related Side Effects and Adverse Reactions
 Necrosis Antibodies  >1 publications with MYL6 and Necrosis
 Adenocarcinoma Antibodies  >1 publications with MYL6 and Adenocarcinoma
 Poisoning Antibodies  >1 publications with MYL6 and Poisoning
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >3 publications with MYL6 and Muscle
 Liver Antibodies  >2 publications with MYL6 and Liver
 Mouth Antibodies  >1 publications with MYL6 and Mouth
 Testis Antibodies  >1 publications with MYL6 and Testis
 Skin Antibodies  >1 publications with MYL6 and Skin
 Brain Antibodies  >1 publications with MYL6 and Brain
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