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MDH1 recombinant protein :: Malate Dehydrogenase 1 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS142414 MDH1 recombinant protein
Unit / Price
1000 IU  /  $140 +1 FREE 8GB USB
5000 IU  /  $205 +1 FREE 8GB USB
50000 IU  /  $1,020 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Malate Dehydrogenase 1 (MDH1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Malate Dehydrogenase 1

 Product Synonym Names    MDH1 Chicken; Malate Dehydrogenase Chicken Recombinant; Malate dehydrogenase cytoplasmic; EC 1.1.1.37; Cytosolic malate dehydrogenase; MDHA; MOR2; MDH-s; MGC:1375; MDH1
 Product Gene Name   

MDH1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q5ZME2
 Host    E Coli
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 Purity/Purification    Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
 Form/Format    Each mg of protein contains 0.59mg NaPO4.
Sterile lyophilized powder.
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 Unit Defenition    One unit is defined as 1 umol of NAD+ production per minute under the assay conditions (25 degree C, pH 7.5).
 Specific Activity    Specific Activity Greater than 710U/mg protein.
 Solubility    It is recommended to reconstitute the lyophilized Malate dehydrogenase in sterile 18M Omega -cm H2O.
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 Preparation and Storage    Lyophilized Malate dehydrogenase although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution MDH1 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.Please prevent freeze-thaw cycles.
 Other Notes    Small volumes of MDH1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for MDH1 recombinant protein

   Description: The DNA encoding Malate (Malic) Dehydrogenase is cloned from cDNA library of chicken heart.The MDH1 is purified by proprietary chromatographic techniques.

Introduction: Malate dehydrogenase (EC1.1.1.37) is an enzyme in the citric acid cycle that catalyzes the conversion of malate into oxaloacetate (using NAD+) and vice versa (this is a reversible reaction). Malate dehydrogenase is not to be confused with malic enzyme, which catalyzes the conversion of pyruvate using NADPH.Malate dehydrogenase is also involved in gluconeogenesis, the synthesis of glucose from smaller molecules. Pyruvate in the mitochondria is acted upon by pyruvate carboxylase to form oxaloacetate, a citric acid cycle intermediate. In order to get the oxaloacetate out of the mitochondria, malate dehydrogenase reduces it to malate, and it then traverses the inner mitochondrial membrane. Once in the cytosol, the malate is oxidized back to oxaloacetate by cytosolic malate dehydrogenase. Finally, phosphoenol-pyruvate carboxy kinase (PEPCK) converts oxaloacetate to phosphoenol pyruvate.
 Product Categories/Family for MDH1 recombinant protein    ENZYMES; Enzymes; Dehydrogenase
NCBI/Uniprot data below describe general gene information for MDH1. It may not necessarily be applicable to this product.
 NCBI GI #    57530355
 NCBI GeneID    421281
 NCBI Accession #    NP_001006395.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001006395.1 [Other Products]
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 UniProt Primary Accession #    Q5ZME2 [Other Products]
 UniProt Related Accession #    Q5ZME2 [Other Products]
 Molecular Weight    36,543 Da
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 NCBI Official Full Name    malate dehydrogenase, cytoplasmic
 NCBI Official Synonym Full Names    malate dehydrogenase 1, NAD (soluble)
 NCBI Official Symbol    MDH1 [Similar Products]
 NCBI Protein Information    malate dehydrogenase, cytoplasmic; cytosolic malate dehydrogenase
 UniProt Protein Name    Malate dehydrogenase, cytoplasmic
 UniProt Synonym Protein Names   
Cytosolic malate dehydrogenase
 Protein Family    Malate dehydrogenase
 UniProt Gene Name    MDH1 [Similar Products]
 UniProt Entry Name    MDHC_CHICK
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MDH1 recombinant proteinPathways associated with MDH1 recombinant protein
 Reference Product  PubMed Publications
 MDH2 recombinant protein  >37 publications with MDH1 and MDH2
 ME1 recombinant protein  >5 publications with MDH1 and ME1
 GOT1 recombinant protein  >5 publications with MDH1 and GOT1
 GOT2 recombinant protein  >3 publications with MDH1 and GOT2
 PCK1 recombinant protein  >1 publications with MDH1 and PCK1
 Products by Pathway  Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Citrate Cycle (TCA Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle) Pathway Diagram
 Citrate Cycle (TCA Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle) Pathway Diagram
 Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway Diagram
 Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway Diagram
 Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway antibodies  Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway Diagram
 Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway antibodies  Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
Diseases associated with MDH1 recombinant proteinOrgans/Tissues associated with MDH1 recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >5 publications with MDH1 and Nervous System Diseases
 Brain Diseases Antibodies  >3 publications with MDH1 and Brain Diseases
 Disease Models, Animal Antibodies  >2 publications with MDH1 and Disease Models, Animal
 Heart Diseases Antibodies  >2 publications with MDH1 and Heart Diseases
 Vascular Diseases Antibodies  >2 publications with MDH1 and Vascular Diseases
 Neurobehavioral Manifestations Antibodies  >1 publications with MDH1 and Neurobehavioral Manifestations
 Dyslipidemias Antibodies  >1 publications with MDH1 and Dyslipidemias
 Seizures Antibodies  >1 publications with MDH1 and Seizures
 Kidney Diseases Antibodies  >1 publications with MDH1 and Kidney Diseases
 Fibrosis Antibodies  >1 publications with MDH1 and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Other Antibodies  >28 publications with MDH1 and Other
 Brain Antibodies  >10 publications with MDH1 and Brain
 Muscle Antibodies  >6 publications with MDH1 and Muscle
 Liver Antibodies  >5 publications with MDH1 and Liver
 Heart Antibodies  >4 publications with MDH1 and Heart
 Small Intestine Antibodies  >2 publications with MDH1 and Small Intestine
 Spleen Antibodies  >2 publications with MDH1 and Spleen
 Gonad Antibodies  >1 publications with MDH1 and Gonad
 Embryonic Tissue Antibodies  >1 publications with MDH1 and Embryonic Tissue
 Adipose Tissue Antibodies  >1 publications with MDH1 and Adipose Tissue
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