NP_004659.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
maltase-glucoamylase, intestinal
NCBI Official Synonym Full Names
maltase-glucoamylase (alpha-glucosidase)
NCBI Official Synonym Symbols
NCBI Protein Information
maltase-glucoamylase, intestinal; alpha-glucosidase; brush border hydrolase
UniProt Protein Name
Maltase-glucoamylase, intestinal
UniProt Synonym Protein Names
Alpha-glucosidase
UniProt Synonym Gene Names
UniProt Entry Name
MGA_HUMAN
NCBI Summary for MGA
This gene encodes maltase-glucoamylase, which is a brush border membrane enzyme that plays a role in the final steps of digestion of starch. The protein has two catalytic sites identical to those of sucrase-isomaltase, but the proteins are only 59% homologous. Both are members of glycosyl hydrolase family 31, which has a variety of substrate specificities. [provided by RefSeq, Jul 2008]
UniProt Comments for MGA
MGAM: May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing. Belongs to the glycosyl hydrolase 31 family.
Protein type: EC 3.2.1.3; Carbohydrate Metabolism - galactose; Membrane protein, integral; Carbohydrate Metabolism - starch and sucrose; EC 3.2.1.20; Hydrolase
Chromosomal Location of Human Ortholog: 7q34
Cellular Component: apical plasma membrane; plasma membrane; integral to membrane
Molecular Function: alpha-glucosidase activity; amylase activity; glucan 1,4-alpha-glucosidase activity; maltase activity; carbohydrate binding; catalytic activity
Biological Process: polysaccharide digestion; carbohydrate metabolic process; pathogenesis; starch catabolic process
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Products associated with MGA recombinant protein
Pathways associated with MGA recombinant protein
Diseases associated with MGA recombinant protein
Organs/Tissues associated with MGA recombinant protein
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