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MBL recombinant protein :: Mannose Binding Lectin (MBL) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2011628 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
SDS-PAGE
Unit / Price
0.01 mg  /  $130 +1 FREE 8GB USB
0.05 mg  /  $225 +1 FREE 8GB USB
0.1 mg  /  $340 +1 FREE 8GB USB
0.2 mg  /  $415 +1 FREE 8GB USB
0.5 mg  /  $800 +1 FREE 8GB USB
1 mg  /  $1,180 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Mannose Binding Lectin (MBL), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mannose Binding Lectin (MBL)

 Product Gene Name   

MBL recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSG S-ET LTEGAQSSCP VIACSSPGLN GFPGKDGHDG AKGEKGEPGQ GLRGLQGPPG KVGPAGPPGN PGSKGATGPK GDRGESVEFD TTNIDLEIAA LRSELRAMRK WVLLSMSENV GKKYFMSSVR RMPLNRAKAL CSELQGTVAT PRNAEENRAI QNVAKDVAFL GITDQRTENV FEDLTGNRVR YTNWNEGEPN NVGSGENCVV LLTNGKWNDV PCSDSFLVVC EFSD
 Chromosome Location    Chromosome: 1; NC_005100.3 (255681084..255688683). Location: 1q51-q55
 3D Structure    ModBase 3D Structure for P08661
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 Host    E Coli
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 Purity/Purification    > 95%
 Form/Format    Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
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 Organism    Rattus norvegicus (Rat)
 Expression System    Prokaryotic expression
 Residues    Glu19~Asp244 (Accession # P08661) with N-terminal His-Tag
 Endotoxin Level    <1.0EU per 1ug (determined by the LAL method)
 Reconstitution    Reconstitute in sterile PBS, pH7.2-pH7.4.
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 Preparation and Storage    Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of MBL recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for MBL recombinant protein

   About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
 Applications Tested/Suitable for MBL recombinant protein   

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

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 SDS-PAGE of MBL recombinant protein    MBL recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for MBL. It may not necessarily be applicable to this product.
 NCBI GI #    148747321
 NCBI GeneID    64668
 NCBI Accession #    NP_073195.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_022704.2 [Other Products]
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 UniProt Primary Accession #    P08661 [Other Products]
 UniProt Related Accession #    P08661 [Other Products]
 Molecular Weight    25.3kDa
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 NCBI Official Full Name    mannose-binding protein C
 NCBI Official Synonym Full Names    mannose-binding lectin (protein C) 2
 NCBI Official Symbol    Mbl2 [Similar Products]
 NCBI Official Synonym Symbols   
Ab2-001; Ab2-011
[Similar Products]
 NCBI Protein Information    mannose-binding protein C; MBP-C; RARF/P28A; raRF p28A; mannan-binding protein; RA-reactive factor P28A subunit; mannose-binding protein C (liver); mannose binding lectin 2 (protein C); ra-reactive factor polysaccharide-binding component p28A
 UniProt Protein Name    Mannose-binding protein C
 UniProt Synonym Protein Names   
Mannan-binding protein; Ra-reactive factor polysaccharide-binding component p28A
 Protein Family    MreB-like protein
 UniProt Gene Name    Mbl2 [Similar Products]
 UniProt Synonym Gene Names    MBP-C; RaRF p28A [Similar Products]
 UniProt Entry Name    MBL2_RAT
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 UniProt Comments for MBL    Function: Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages

By similarity.

Subunit structure: Oligomeric complex of 3 or more homotrimers. Interacts with MASP1 and MASP2

By similarity. Interacts with MEP1A and MEP1B and may inhibit their catalytic activity

By similarity.

Subcellular location: Secreted

By similarity Ref.4.

Sequence similarities: Contains 1 C-type lectin domain.Contains 1 collagen-like domain.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with MBL recombinant proteinDiseases associated with MBL recombinant protein
 Products by Pathway  Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Staphylococcus Aureus Infection Pathway antibodies  Staphylococcus Aureus Infection Pathway Diagram
 Staphylococcus Aureus Infection Pathway antibodies  Staphylococcus Aureus Infection Pathway Diagram
 Disease Name  Pubmed Publications
 Infection Antibodies  >185 publications with MBL and Infection
 Inflammation Antibodies  >75 publications with MBL and Inflammation
 Neoplasms Antibodies  >46 publications with MBL and Neoplasms
 Liver Diseases Antibodies  >30 publications with MBL and Liver Diseases
 Fibrosis Antibodies  >24 publications with MBL and Fibrosis
 HIV Infections Antibodies  >23 publications with MBL and HIV Infections
 Heart Diseases Antibodies  >18 publications with MBL and Heart Diseases
 Necrosis Antibodies  >17 publications with MBL and Necrosis
 Disease Models, Animal Antibodies  >13 publications with MBL and Disease Models, Animal
 Premature Birth Antibodies  >12 publications with MBL and Premature Birth
Organs/Tissues associated with MBL recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >44 publications with MBL and Liver
 Brain Antibodies  >8 publications with MBL and Brain
 Mixed Antibodies  >3 publications with MBL and Mixed
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