XP_521864.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
36,849 Da
NCBI Official Full Name
mas-related G-protein coupled receptor member X2
NCBI Official Synonym Symbols
NCBI Protein Information
mas-related G-protein coupled receptor member X2
UniProt Protein Name
Mas-related G-protein coupled receptor member X2
UniProt Synonym Gene Names
UniProt Entry Name
MRGX2_PANTR
UniProt Comments for MRGPRX2
Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction.
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Diseases associated with MRGPRX2 recombinant protein
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