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SERPINB5 recombinant protein :: Maspin Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS203332
SDS-Page
Unit / Price
0.1 mg  /  $310 +1 FREE 8GB USB
0.5 mg  /  $720 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Maspin (SERPINB5), Recombinant Protein

★Popular Item★
 Also Known As   

Maspin, 1-375aa, Human, His tag, E Coli

 Product Synonym Names    Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5; Serpin B5; Protease inhibitor 5; SERPINB5; PI5; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5 Serine (or cysteine) peptidase inhibitor; clade B; member 5; Ovalbumin; PI-5; Serpin peptidase inhibitor; Serpin peptidase inhibitor; clade B (ovalbumin); member 5; SERPINB5; Spi5; Spi7.
 Product Gene Name   

SERPINB5 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS203332 MSDS    MSDS PDF
 Sequence    MGSSHHHHHH SSGLVPRGSH MDALQLANSA FAVDLFKQLC EKEPLGNVLF SPICLSTSLS LAQVGAKGDT ANEIGQVLHF ENVKDVPFGF QTVTSDVNKL SSFYSLKLIK RLYVDKSLNL STEFISSTKR PYAKELETVD FKDKLEETKG QINNSIKDLT DGHFENILAD NSVNDQTKIL VVNAAYFVGK WMKKFPESET KECPFRVNKT DTKPVQMMNM EATFCMGNID SINCKIMELP FQNKHLSMFI LLPKDVEDES TGLEKIEKQL NSESLSQWTN PSTMANAKVK LSIPKFKVEK MIDPKACLEN LGLKHIFSED TSDFSGMSET KGVALSNVIH KVCLEITEDG GDSIEVPGAR ILQHKDELNA DHPFIYIIRH NKTRNIIFFG KFCSP
 OMIM    U04313 mRNA
 3D Structure    ModBase 3D Structure for P36952
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 Host    E Coli
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 Purity/Purification    > 95% by SDS-PAGE
 Form/Format    Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 1mM DTT, 10% glycerol.
 Concentration    1 mg/ml (determined by Bradford assay) (lot specific)
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 Antigen Species    Human
 Tag Information    His-tag
 Endotoxin Level    < 1.0 EU per 1 microgram of protein (determined by LAL method)
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of SERPINB5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for SERPINB5 recombinant protein

   Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5, also known as Maspin, is a tumor suppressor protein of serine proteinase inhibitor family. It plays an essential role in embryonic development through critical roles in cell adhesion. Also, it is present in normal breast and prostatic epithelial cells but downregulated in the respective carcinomas. Recombinant human Maspin, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography.
 Product Categories/Family for SERPINB5 recombinant protein    Proteases & Inhibitors
 Applications Tested/Suitable for SERPINB5 recombinant protein   

SDS-PAGE

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 SDS-Page of SERPINB5 recombinant protein    SERPINB5 recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for SERPINB5. It may not necessarily be applicable to this product.
 NCBI GI #    167860126
 NCBI GeneID    5268
 NCBI Accession #    NP_002630 [Other Products]
 NCBI GenBank Nucleotide #    NM_002639.4 [Other Products]
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 UniProt Primary Accession #    P36952 [Other Products]
 UniProt Secondary Accession #    Q6N0B4; Q8WW89; B2R6Y4 [Other Products]
 UniProt Related Accession #    P36952 [Other Products]
 Molecular Weight    44.2 kDa (395aa), confirmed by MALDI-TOF. [Similar Products]
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 NCBI Official Full Name    serpin B5
 NCBI Official Synonym Full Names    serpin family B member 5
 NCBI Official Symbol    SERPINB5 [Similar Products]
 NCBI Official Synonym Symbols   
PI5; maspin
[Similar Products]
 NCBI Protein Information    serpin B5
 UniProt Protein Name    Serpin B5
 UniProt Synonym Protein Names   
Maspin; Peptidase inhibitor 5; PI-5
 Protein Family    Serpin
 UniProt Gene Name    SERPINB5 [Similar Products]
 UniProt Synonym Gene Names    PI5; PI-5 [Similar Products]
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 UniProt Comments for SERPINB5    Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
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Product References and Citations for SERPINB5 recombinant protein

   Lockett J., et al. (2006). J Cell Biochem. 97 (4):651-60.; Khalkhali Ellis Z., et al. (2006). Clin Cancer Res. 12 (24):7279-83.;
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 Research Articles on SERPINB5    1. Study results provide new insights into the molecular mechanisms of maspin suppression in response to HBx, and revealed nuclear IKKalpha as a prognostic biomarker and a potential therapeutic target to improve the clinical outcome of HBV-associated HCC patients.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SERPINB5 recombinant proteinPathways associated with SERPINB5 recombinant protein
 Reference Product  PubMed Publications
 TP53 recombinant protein  >4 publications with SERPINB5 and TP53
 PLAU recombinant protein  >3 publications with SERPINB5 and PLAU
 IL6 recombinant protein  >1 publications with SERPINB5 and IL6
 Products by Pathway  Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 P53 Signaling Pathway antibodies  P53 Signaling Pathway Diagram
 P53 Signaling Pathway antibodies  P53 Signaling Pathway Diagram
Diseases associated with SERPINB5 recombinant proteinOrgans/Tissues associated with SERPINB5 recombinant protein
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >18 publications with SERPINB5 and Carcinoma
 Breast Neoplasms Antibodies  >16 publications with SERPINB5 and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >13 publications with SERPINB5 and Neoplasm Metastasis
 Adenocarcinoma Antibodies  >10 publications with SERPINB5 and Adenocarcinoma
 Inflammation Antibodies  >8 publications with SERPINB5 and Inflammation
 Neoplasm Invasiveness Antibodies  >8 publications with SERPINB5 and Neoplasm Invasiveness
 Neoplasms, Experimental Antibodies  >7 publications with SERPINB5 and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >6 publications with SERPINB5 and Lung Neoplasms
 Colorectal Neoplasms Antibodies  >5 publications with SERPINB5 and Colorectal Neoplasms
 Pancreatic Neoplasms Antibodies  >5 publications with SERPINB5 and Pancreatic Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >9 publications with SERPINB5 and Lung
 Prostate Antibodies  >6 publications with SERPINB5 and Prostate
 Bone Antibodies  >5 publications with SERPINB5 and Bone
 Intestine Antibodies  >4 publications with SERPINB5 and Intestine
 Muscle Antibodies  >3 publications with SERPINB5 and Muscle
 Stomach Antibodies  >3 publications with SERPINB5 and Stomach
 Pancreas Antibodies  >3 publications with SERPINB5 and Pancreas
 Heart Antibodies  >2 publications with SERPINB5 and Heart
 Uterus Antibodies  >2 publications with SERPINB5 and Uterus
 Bladder Antibodies  >2 publications with SERPINB5 and Bladder
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