NP_066245.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
39.1 kDa
NCBI Official Full Name
matrix protein
NCBI Protein Information
matrix protein
UniProt Protein Name
Matrix protein VP40
UniProt Synonym Protein Names
Membrane-associated protein VP40
UniProt Entry Name
VP40_EBOZ5
UniProt Comments for VP40
Promotes virus assembly and budding by interacting with host proteins of the multivesicular body pathway. May facilitate virus budding by interacting with the nucleocapsid and the plasma membrane. Specific interactions with membrane-associated GP and VP24 during the budding process may also occur. The hexamer form seems to be involved in budding. The octamer form binds RNA, and may play a role in genome replication ().
Product References and Citations for VP40 recombinant protein
Chain P.S.G., Ichou M.A., Malfatti S.A., Hajjaj A., Vergez L.M., Paragas J., Do L.H., Jahrling P.B., Smith K.L., McCready P.M., Ibrahim M.S.Crystal structure of the matrix protein VP40 from Ebola virus.Dessen A., Volchkov V., Dolnik O., Klenk H.-D., Weissenhorn W.EMBO J. 19:4228-4236(2000)
Research Articles on VP40
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