NP_001135418.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
61,924 Da
NCBI Official Full Name
McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin isoform 1
NCBI Official Synonym Full Names
McKusick-Kaufman syndrome
NCBI Official Synonym Symbols
Bbs6; AI463362; AI957237; 1300013E18Rik [Similar Products]
NCBI Protein Information
McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin
UniProt Protein Name
McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin
UniProt Synonym Protein Names
Protein Bbs6 homolog
UniProt Synonym Gene Names
NCBI Summary for Mkks
This gene encodes a protein which shares sequence similarity with other members of the type II chaperonin family. The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis. This protein also interacts with other type II chaperonin members to form a complex known as the BBSome, which involves ciliary membrane biogenesis. This protein is encoded by a downstream open reading frame (dORF). Several upstream open reading frames (uORFs) have been identified, which repress the translation of the dORF, and two of which can encode small mitochondrial membrane proteins. Alternatively spliced transcripts encoding distinct isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
UniProt Comments for Mkks
Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis (). As part of the BBS/CCT complex plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:28753627). May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis ().
Research Articles on Mkks
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Products associated with Mkks recombinant protein
Diseases associated with Mkks recombinant protein
Organs/Tissues associated with Mkks recombinant protein
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