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Acadm recombinant protein :: Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (Acadm) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS967853 Acadm recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $810 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $915 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,045 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,080 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,195 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,230 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,295 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,325 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,395 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,695 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,905 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,955 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,115 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,515 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (Acadm), Recombinant Protein

 Also Known As   

Recombinant Rat Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (Acadm)

 Product Synonym Names    Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; MCAD; EC=1.3.99.3
 Product Gene Name   

Acadm recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    26-421aa; Full length protein
 Sequence    KPSLK QEPGLGFSFE LTEQQKEFQT IARKFAREEI IPVAPDYDKS GEYPFPLIKR AWELGLINTH IPESCGGLGL GTFDACLITE ELAYGCTGVQ TAIEANSLGQ MPVIIAGNDQ QKKKYLGRMT EQPMMCAYCV TEPSAGSDVA GIKTKAEKKG DEYVINGQKM WITNGGKANW YFVLTRSNPD PKVPASKAFT GFIVEADTPG IHIGKKELNM GQRCSDTRGI TFEDVRVPKE NVLIGEGAGF KIAMGAFDRT RPTVAAGAVG LAQRALDEAT KYALDRKTFG KLLVEHQGVS FLLAEMAMKV ELARLSYQRA AWEVDSGRRN TYFASIAKAF AGDIANQLAT DAVQIFGGYG FNTEYPVEKL MRDAKIYQIY EGTAQIQRLI IAREHIEKYK N
 3D Structure    ModBase 3D Structure for P08503
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rattus norvegicus (Rat)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Acadm recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for Acadm recombinant protein

   This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI/Uniprot data below describe general gene information for Acadm. It may not necessarily be applicable to this product.
 NCBI GI #    292494885
 NCBI GeneID    24158
 NCBI Accession #    NP_058682.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_016986.2 [Other Products]
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 UniProt Primary Accession #    P08503 [Other Products]
 UniProt Related Accession #    P08503 [Other Products]
 Molecular Weight    46,555 Da
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 NCBI Official Full Name    medium-chain specific acyl-CoA dehydrogenase, mitochondrial
 NCBI Official Synonym Full Names    acyl-CoA dehydrogenase, C-4 to C-12 straight chain
 NCBI Official Symbol    Acadm [Similar Products]
 NCBI Official Synonym Symbols   
MCAD
[Similar Products]
 NCBI Protein Information    medium-chain specific acyl-CoA dehydrogenase, mitochondrial; medium-chain acyl-CoA dehydrogenase; acyl-Coenzyme A dehydrogenase, medium chain; Acyl-Coenzyme A dehydrogenase C-4 to C-12 straight-chain; Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight-chain; acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain
 UniProt Protein Name    Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
 Protein Family    Medium-chain specific acyl-CoA dehydrogenase
 UniProt Gene Name    Acadm [Similar Products]
 UniProt Synonym Gene Names    MCAD [Similar Products]
 UniProt Entry Name    ACADM_RAT
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 NCBI Summary for Acadm    catalyzes the alpha, beta-dehydrogenation of acyl-CoA esters in fatty acid metabolism [RGD, Feb 2006]
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 UniProt Comments for Acadm    ACADM: This enzyme is specific for acyl chain lengths of 4 to 16

Protein type: Mitochondrial; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Other Amino Acids Metabolism - beta-alanine; Carbohydrate Metabolism - propanoate; EC 1.3.8.7; Oxidoreductase; Lipid Metabolism - fatty acid
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 Research Articles on Acadm    1. High fat diets increase the expression of fatty acid oxidation enzymes such as UCP3,PDK4, and MCAD concomitant with elevated plasma fatty acid levels and the induction of PGC-1 beta, but independent of changes in AMPK, p38, and PKA signaling.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Acadm recombinant proteinPathways associated with Acadm recombinant protein
 Reference Product  PubMed Publications
 Acsl1 recombinant protein  >2 publications with Acadm and Acsl1
 Acsl5 recombinant protein  >1 publications with Acadm and Acsl5
 Echs1 recombinant protein  >1 publications with Acadm and Echs1
 Acaa2 recombinant protein  >1 publications with Acadm and Acaa2
 Ehhadh recombinant protein  >1 publications with Acadm and Ehhadh
 Hadhb recombinant protein  >1 publications with Acadm and Hadhb
 Products by Pathway  Pathway Diagram
 Beta Oxidation Meta Pathway antibodies  Beta Oxidation Meta Pathway Diagram
 Beta Oxidation Of Unsaturated Fatty Acids Pathway antibodies  Beta Oxidation Of Unsaturated Fatty Acids Pathway Diagram
 Beta Oxidation Of Decanoyl-CoA To Octanoyl-CoA-CoA Pathway antibodies  Beta Oxidation Of Decanoyl-CoA To Octanoyl-CoA-CoA Pathway Diagram
 Beta Oxidation Of Octanoyl-CoA To Hexanoyl-CoA Pathway antibodies  Beta Oxidation Of Octanoyl-CoA To Hexanoyl-CoA Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Fatty Acid Beta Oxidation Pathway antibodies  Fatty Acid Beta Oxidation Pathway Diagram
 Fatty Acid Beta Oxidation 2 Pathway antibodies  Fatty Acid Beta Oxidation 2 Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram
Diseases associated with Acadm recombinant proteinOrgans/Tissues associated with Acadm recombinant protein
 Disease Name  Pubmed Publications
 Medium chain acyl CoA dehydrogenase deficiency Antibodies  >20 publications with Acadm and Medium chain acyl CoA dehydrogenase deficiency
 Fatty Liver Antibodies  >9 publications with Acadm and Fatty Liver
 Obesity Antibodies  >4 publications with Acadm and Obesity
 Cardiovascular Diseases Antibodies  >4 publications with Acadm and Cardiovascular Diseases
 Liver Diseases Antibodies  >3 publications with Acadm and Liver Diseases
 Heart Diseases Antibodies  >3 publications with Acadm and Heart Diseases
 Inflammation Antibodies  >2 publications with Acadm and Inflammation
 Insulin Resistance Antibodies  >2 publications with Acadm and Insulin Resistance
 Disease Models, Animal Antibodies  >2 publications with Acadm and Disease Models, Animal
 Fibrosis Antibodies  >1 publications with Acadm and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >9 publications with Acadm and Liver
 Heart Antibodies  >5 publications with Acadm and Heart
 Muscle Antibodies  >4 publications with Acadm and Muscle
 Adipose Tissue Antibodies  >4 publications with Acadm and Adipose Tissue
 Connective Tissue Antibodies  >3 publications with Acadm and Connective Tissue
 Kidney Antibodies  >3 publications with Acadm and Kidney
 Brain Antibodies  >2 publications with Acadm and Brain
 Pancreas Antibodies  >2 publications with Acadm and Pancreas
 Prostate Antibodies  >1 publications with Acadm and Prostate
 Embryonic Tissue Antibodies  >1 publications with Acadm and Embryonic Tissue
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