Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow MSLN  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Caspase 6 (Cleaved-Asp179) (CASP6) Antibody
 • MCPH1 Antibody
 • ATF-4 (Ab-219) Antibody
 • Peptidyl Prolyl Cis-Trans Isomerase Nima Interacting 4 Prote... ELISA Kit
 • Glycoprotein VI, Platelet (GP6) ELISA Kit
 • Phospho Tau Protein (PHOSPHO-TAU) ELISA Kit
 • Centriole and Centrosome Antibody IgA (CA-IgA) ELISA Kit
 • Pentosidine ELISA Kit
 • Hydroxy-Pyridinium Crosslinks (OH-PYD) ELISA Kit
 • Growth Differentiation Factor 2 (GDF2) ELISA Kit
 • Kinase Insert Domain Receptor-Vegfr2 (KDR) ELISA Kit
 • CXC-Chemokine Receptor 2 (CXCR2) ELISA Kit
 • Attractin (ATRN) ELISA Kit
 • Glial Fibrillary Acidic Protein (GFAP) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

MSLN recombinant protein :: Mesothelin (MSLN) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2010411 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
SDS-PAGE
Unit / Price
0.01 mg  /  $175 +1 FREE 8GB USB
0.05 mg  /  $375 +1 FREE 8GB USB
0.1 mg  /  $580 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Mesothelin (MSLN), Recombinant Protein

 Also Known As   

Recombinant Mesothelin (MSLN)

 Product Gene Name   

MSLN recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence    The target protein is fused with two N-terminal Tags, His-tag and GST-tag, its sequence is listed below.
MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTLEV LFQGPLGSEF - PFTYEQ LSIFKHKLDK TYPQGYPESL IQQLGHFFRY VSPEDIHQWN VTSPDTVKTL LKVSKGQKMN AQAIALVACY LRGGGQLDED MVKALGDIPL SYLCDFSPQD LHSVPSSVMW LVGPQDLDKC SQRHLGLLYQ KACSAFQNVS GLEYFEKIKT FLGGASVKDL RALSQHNVSM DIATFKRLQV DSLVGLSVAE VQKLLGPN
 Chromosome Location    Chromosome: 17; NC_000083.6 (25748613..25754446, complement). Location: 17 A3.3; 17
 3D Structure    ModBase 3D Structure for Q61468
Section Bar
 Host    E Coli
Section Bar
 Purity/Purification    > 95%
 Form/Format    Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Section Bar
 Organism    Mus musculus (Mouse)
 Expression System    Prokaryotic expression
 Residues    Pro345~Asn548 (Accession # Q61468) with two N-terminal Tags, His-tag and GST-tag
 Subcellular Location    Cell membrane; Secreted, Lipid-anchor, GPI-anchor, Golgi apparatus
 Endotoxin Level    <1.0EU per 1ug (determined by the LAL method)
 Predicted Isoelectric Point    6.4
 Reconstitution    Reconstitute in sterile PBS, pH7.2-pH7.4.
Section Bar
 Preparation and Storage    Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of MSLN recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for MSLN recombinant protein

   About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
 Applications Tested/Suitable for MSLN recombinant protein   

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

Section Bar
 SDS-PAGE of MSLN recombinant protein    MSLN recombinant protein SDS-PAGE image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for MSLN. It may not necessarily be applicable to this product.
 NCBI GI #    9256568
 NCBI GeneID    56047
 NCBI Accession #    NP_061345.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_018857.1 [Other Products]
Section Bar
 UniProt Primary Accession #    Q61468 [Other Products]
 UniProt Related Accession #    Q61468 [Other Products]
 Molecular Weight    54.7kDa
Table BarTOPTable Bar
 NCBI Official Full Name    mesothelin
 NCBI Official Synonym Full Names    mesothelin
 NCBI Official Symbol    Msln [Similar Products]
 NCBI Official Synonym Symbols   
MPF
[Similar Products]
 NCBI Protein Information    mesothelin; megakaryocyte potentiating factor; pre-pro-megakaryocyte-potentiating factor
 UniProt Protein Name    Mesothelin
 UniProt Synonym Protein Names   
Pre-pro-megakaryocyte-potentiating factor
 Protein Family    Mesothelin
 UniProt Gene Name    Msln [Similar Products]
 UniProt Synonym Gene Names    Mes; Mpf; MPF [Similar Products]
 UniProt Entry Name    MSLN_MOUSE
Section Bar
 UniProt Comments for MSLN    MSLN: Membrane-anchored forms may play a role in cellular adhesion. Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer. Belongs to the mesothelin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor; Cell adhesion

Cellular Component: Golgi apparatus; extracellular space; cell surface; membrane; extracellular region; plasma membrane

Molecular Function: protein binding

Biological Process: cell adhesion
Table BarTOPTable Bar
 Research Articles on MSLN    1. The mesothelin expression promotes resistance to certain chemotherapy drugs such as TNF-alpha, paclitaxel, and a combination of platinum and cyclophosphamide.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with MSLN recombinant proteinDiseases associated with MSLN recombinant protein
 Reference Product  PubMed Publications
 Wfdc2 recombinant protein  >1 publications with MSLN and Wfdc2
 Disease Name  Pubmed Publications
 Mesothelioma Antibodies  >15 publications with MSLN and Mesothelioma
 Carcinoma Antibodies  >15 publications with MSLN and Carcinoma
 Pancreatic Neoplasms Antibodies  >13 publications with MSLN and Pancreatic Neoplasms
 Adenocarcinoma Antibodies  >13 publications with MSLN and Adenocarcinoma
 Neoplasms, Mesothelial Antibodies  >11 publications with MSLN and Neoplasms, Mesothelial
 Ovarian Neoplasms Antibodies  >9 publications with MSLN and Ovarian Neoplasms
 Carcinoma, Pancreatic Ductal Antibodies  >5 publications with MSLN and Carcinoma, Pancreatic Ductal
 Neoplasms, Experimental Antibodies  >5 publications with MSLN and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >5 publications with MSLN and Lung Neoplasms
 Lymphatic Metastasis Antibodies  >4 publications with MSLN and Lymphatic Metastasis
Organs/Tissues associated with MSLN recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >10 publications with MSLN and Lung
 Liver Antibodies  >5 publications with MSLN and Liver
 Pancreas Antibodies  >3 publications with MSLN and Pancreas
 Ovary Antibodies  >3 publications with MSLN and Ovary
 Stomach Antibodies  >2 publications with MSLN and Stomach
 Kidney Antibodies  >2 publications with MSLN and Kidney
 Muscle Antibodies  >2 publications with MSLN and Muscle
 Bladder Antibodies  >1 publications with MSLN and Bladder
 Bone Marrow Antibodies  >1 publications with MSLN and Bone Marrow
 Embryonic Tissue Antibodies  >1 publications with MSLN and Embryonic Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions