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MT2 recombinant protein :: Metallothionein 2 (MT2) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2012291 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $115 +1 FREE 8GB USB
0.05 mg  /  $200 +1 FREE 8GB USB
0.1 mg  /  $290 +1 FREE 8GB USB
0.2 mg  /  $360 +1 FREE 8GB USB
0.5 mg  /  $690 +1 FREE 8GB USB
1 mg  /  $1,015 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Metallothionein 2 (MT2), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Metallothionein 2 (MT2)

 Product Gene Name   

MT2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS2012291 Technical Datasheet    Technical Datasheet PDF
 Chromosome Location    Chromosome: 16; NC_000016.9 (56642478..56643409). Location: 16q13
 OMIM    156360
 3D Structure    ModBase 3D Structure for P02795
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 Host    E Coli
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 Purity/Purification    >90%
 Form/Format    Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
 Concentration    Original Concentration: 200 Ug/mL (lot specific)
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 Organism Species    Homo sapiens (Human)
 Source    Prokaryotic expression
 Residues    Asp2~Ala61
 Tags    No-Tag
 Traits    Freeze-dried powder
 Buffer formulation    100mM NaHCO3, 500mM NaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300.
 Predicted isoelectric point    8.3
 Predicted Molecular Mass    5.9kDa
 Accurate Molecular Mass    12kDa as determined by SDS-PAGE reducing conditions.
 Phenomenon explanation    The possible reasons that the actual band size differs from the predicted are as follows:

1. Splice variants: Alternative splicing may create different sized proteins from the same gene.
2. Relative charge: The composition of amino acids may affects the charge of the protein.
3. Post-translational modification: Phosphorylation, glycosylation, methylation etc.
4. Post-translation cleavage: Many proteins are synthesized as pro-proteins, and then cleaved to give the active form.
5. Polymerization of the target protein: Dimerization, multimerization etc.
 USAGE    Reconstitute in 100mM NaHCO3, 500mM NaCl (pH8.3) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8C for one month.
Aliquot and store at -80oC for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of MT2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for MT2 recombinant protein

   About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
 Applications Tested/Suitable for MT2 recombinant protein   

Positive Control, Immunogen, SDS-PAGE, WB.

(May be suitable for use in other assays to be determined by the end user.)

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 Testing Data TD of MT2 recombinant protein    MT2 recombinant protein Testing Data TD image
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 Testing Data TD of MT2 recombinant protein    MT2 recombinant protein Testing Data TD image
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 SDS-PAGE of MT2 recombinant protein    MT2 recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for MT2. It may not necessarily be applicable to this product.
 NCBI GI #    5174764
 NCBI GeneID    4502
 NCBI Accession #    NP_005944.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005953.3 [Other Products]
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 UniProt Primary Accession #    P02795 [Other Products]
 UniProt Secondary Accession #    Q14823; Q2HXR9; Q53XT9 [Other Products]
 UniProt Related Accession #    P02795 [Other Products]
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 NCBI Official Full Name    metallothionein-2
 NCBI Official Synonym Full Names    metallothionein 2A
 NCBI Official Symbol    MT2A [Similar Products]
 NCBI Official Synonym Symbols   
MT2
[Similar Products]
 NCBI Protein Information    metallothionein-2; MT-2; MT-II; metallothionein-2A; metallothionein-II
 UniProt Protein Name    Metallothionein-2
 UniProt Synonym Protein Names   
Metallothionein-2A; Metallothionein-II
 Protein Family    Metallothionein
 UniProt Gene Name    MT2A [Similar Products]
 UniProt Synonym Gene Names    CES1; MT2; MT-2; MT-II [Similar Products]
 UniProt Entry Name    MT2_HUMAN
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 UniProt Comments for MT2    MT2A: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. Belongs to the metallothionein superfamily. Type 1 family.

Protein type: Carrier

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: perinuclear region of cytoplasm; cytoplasm; cytosol; nucleus

Molecular Function: protein binding; zinc ion binding; drug binding

Biological Process: cellular copper ion homeostasis; cytokine and chemokine mediated signaling pathway; negative regulation of growth
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 Research Articles on MT2    1. Cotreatment with aryl hydrocarbon receptor agonist and dexamethasone enhances human MT2A gene expression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MT2 recombinant proteinPathways associated with MT2 recombinant protein
 Reference Product  PubMed Publications
 MT1G recombinant protein  >8 publications with MT2 and MT1G
 MT1H recombinant protein  >7 publications with MT2 and MT1H
 HIPK2 recombinant protein  >1 publications with MT2 and HIPK2
 SPINK7 recombinant protein  >1 publications with MT2 and SPINK7
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Interferon Signaling Pathway antibodies  Interferon Signaling Pathway Diagram
 Interferon Gamma Signaling Pathway antibodies  Interferon Gamma Signaling Pathway Diagram
 Mineral Absorption Pathway antibodies  Mineral Absorption Pathway Diagram
 Mineral Absorption Pathway antibodies  Mineral Absorption Pathway Diagram
Diseases associated with MT2 recombinant proteinOrgans/Tissues associated with MT2 recombinant protein
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >35 publications with MT2 and Neoplasms
 Inflammation Antibodies  >14 publications with MT2 and Inflammation
 Carcinoma Antibodies  >12 publications with MT2 and Carcinoma
 Nervous System Diseases Antibodies  >8 publications with MT2 and Nervous System Diseases
 Brain Diseases Antibodies  >6 publications with MT2 and Brain Diseases
 Prostatic Neoplasms Antibodies  >6 publications with MT2 and Prostatic Neoplasms
 Immune System Diseases Antibodies  >6 publications with MT2 and Immune System Diseases
 Cardiovascular Diseases Antibodies  >6 publications with MT2 and Cardiovascular Diseases
 Necrosis Antibodies  >5 publications with MT2 and Necrosis
 Liver Diseases Antibodies  >5 publications with MT2 and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >27 publications with MT2 and Blood
 Liver Antibodies  >14 publications with MT2 and Liver
 Brain Antibodies  >10 publications with MT2 and Brain
 Prostate Antibodies  >8 publications with MT2 and Prostate
 Lung Antibodies  >7 publications with MT2 and Lung
 Muscle Antibodies  >7 publications with MT2 and Muscle
 Intestine Antibodies  >6 publications with MT2 and Intestine
 Vascular Antibodies  >5 publications with MT2 and Vascular
 Heart Antibodies  >5 publications with MT2 and Heart
 Stomach Antibodies  >4 publications with MT2 and Stomach
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