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MT2A recombinant protein :: Metallothionein-2 (MT2A) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS951896 MT2A recombinant protein
Unit / Price
0.01 mg (Yeast)  /  $110 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $190 +1 FREE 8GB USB
0.1 mg (Yeast)  /  $285 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $450 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $460 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $595 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $655 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $750 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $785 +1 FREE 8GB USB
1 mg (E-Coli)  /  $925 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $990 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,025 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,180 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,440 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,570 +1 FREE 8GB USB
1 mg (Baculovirus)  /  $1,935 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Metallothionein-2 (MT2A), Recombinant Protein

 Also Known As   

Recombinant Human Metallothionein-2 (MT2A)

 Product Synonym Names    Metallothionein-2; MT-2; Metallothionein-2A; Metallothionein-II; MT-II
 Product Gene Name   

MT2A recombinant protein

[Similar Products]
 Product Synonym Gene Name    MT2A; CES1; MT2 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-59aa; Partial of the full length of 1-61aa
 Sequence    MDPNCSCAAG DSCTCAGSCK CKECKCTSCK KSCCSCCPVG CAKCAQGCIC KGASDKCSC
 OMIM    156360
 3D Structure    ModBase 3D Structure for P02795
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of MT2A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for MT2A recombinant protein    Epigenetics and Nuclear Signaling
NCBI/Uniprot data below describe general gene information for MT2A. It may not necessarily be applicable to this product.
 NCBI GI #    5174764
 NCBI GeneID    4502
 NCBI Accession #    NP_005944.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005953.3 [Other Products]
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 UniProt Primary Accession #    P02795 [Other Products]
 UniProt Secondary Accession #    Q14823; Q2HXR9; Q53XT9 [Other Products]
 UniProt Related Accession #    P02795 [Other Products]
 Molecular Weight    6,042 Da
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 NCBI Official Full Name    metallothionein-2
 NCBI Official Synonym Full Names    metallothionein 2A
 NCBI Official Symbol    MT2A [Similar Products]
 NCBI Official Synonym Symbols   
MT2
[Similar Products]
 NCBI Protein Information    metallothionein-2; MT-2; MT-II; metallothionein-2A; metallothionein-II
 UniProt Protein Name    Metallothionein-2
 UniProt Synonym Protein Names   
Metallothionein-2A; Metallothionein-II; MT-II
 Protein Family    Metallothionein
 UniProt Gene Name    MT2A [Similar Products]
 UniProt Synonym Gene Names    CES1; MT2; MT-2; MT-II [Similar Products]
 UniProt Entry Name    MT2_HUMAN
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 NCBI Summary for MT2A    This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions, altering the intracellular concentration of heavy metals in the cell. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. The encoded protein interacts with the protein encoded by the homeobox containing 1 gene in some cell types, controlling intracellular zinc levels, affecting apoptotic and autophagy pathways. Some polymorphisms in this gene are associated with an increased risk of cancer. [provided by RefSeq, Sep 2017]
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 UniProt Comments for MT2A    MT2A: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. Belongs to the metallothionein superfamily. Type 1 family.

Protein type: Carrier

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: perinuclear region of cytoplasm; cytoplasm; nucleus; cytosol

Molecular Function: protein binding; zinc ion binding; drug binding

Biological Process: cellular copper ion homeostasis; cytokine and chemokine mediated signaling pathway; negative regulation of growth
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 Research Articles on MT2A    1. Low MT2A expression is associateed with lung carcinogenesis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MT2A recombinant proteinPathways associated with MT2A recombinant protein
 Reference Product  PubMed Publications
 MT1G recombinant protein  >8 publications with MT2A and MT1G
 MT1H recombinant protein  >7 publications with MT2A and MT1H
 HIPK2 recombinant protein  >1 publications with MT2A and HIPK2
 SPINK7 recombinant protein  >1 publications with MT2A and SPINK7
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Interferon Signaling Pathway antibodies  Interferon Signaling Pathway Diagram
 Interferon Gamma Signaling Pathway antibodies  Interferon Gamma Signaling Pathway Diagram
 Mineral Absorption Pathway antibodies  Mineral Absorption Pathway Diagram
 Mineral Absorption Pathway antibodies  Mineral Absorption Pathway Diagram
Diseases associated with MT2A recombinant proteinOrgans/Tissues associated with MT2A recombinant protein
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >35 publications with MT2A and Neoplasms
 Inflammation Antibodies  >14 publications with MT2A and Inflammation
 Nervous System Diseases Antibodies  >8 publications with MT2A and Nervous System Diseases
 Brain Diseases Antibodies  >6 publications with MT2A and Brain Diseases
 Prostatic Neoplasms Antibodies  >6 publications with MT2A and Prostatic Neoplasms
 Immune System Diseases Antibodies  >6 publications with MT2A and Immune System Diseases
 Cardiovascular Diseases Antibodies  >6 publications with MT2A and Cardiovascular Diseases
 Necrosis Antibodies  >5 publications with MT2A and Necrosis
 Atherosclerosis Antibodies  >5 publications with MT2A and Atherosclerosis
 Liver Diseases Antibodies  >5 publications with MT2A and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >28 publications with MT2A and Blood
 Liver Antibodies  >14 publications with MT2A and Liver
 Brain Antibodies  >10 publications with MT2A and Brain
 Prostate Antibodies  >8 publications with MT2A and Prostate
 Lung Antibodies  >7 publications with MT2A and Lung
 Muscle Antibodies  >7 publications with MT2A and Muscle
 Intestine Antibodies  >6 publications with MT2A and Intestine
 Vascular Antibodies  >5 publications with MT2A and Vascular
 Heart Antibodies  >5 publications with MT2A and Heart
 Stomach Antibodies  >4 publications with MT2A and Stomach
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