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MT3 recombinant protein :: Metallothionein-3 (MT3) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS953195
SDS-PAGE
Unit / Price
0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $795 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,020 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,020 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,100 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,560 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,560 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,560 +1 FREE 8GB USB
1 mg (Baculovirus)  /  $2,175 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Metallothionein-3 (MT3), Recombinant Protein

 Also Known As   

Recombinant Human Metallothionein-3 (MT3)

 Product Synonym Names    Metallothionein-3; MT-3; GIFB; GIF; Growth inhibitory factor; Metallothionein-III; MT-III
 Product Gene Name   

MT3 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS953195 COA    COA PDF
 Sequence Positions    1-68, Full length.
 Sequence    MDPETCPCPS GGSCTCADSC KCEGCKCTSC KKSCCSCCPA ECEKCAKDCV CKGGEAAEAE AEKCSCCQ
 OMIM    139255
 3D Structure    ModBase 3D Structure for P25713
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of MT3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 SDS-PAGE of MT3 recombinant protein    Recombinant Human Metallothionein-3(MT3)
His-sumo-tagged
E.Coli derived
MT3 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for MT3. It may not necessarily be applicable to this product.
 NCBI GI #    5174762
 NCBI GeneID    4504
 NCBI Accession #    NP_005945.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005954.2 [Other Products]
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 UniProt Primary Accession #    P25713 [Other Products]
 UniProt Secondary Accession #    Q2V574 [Other Products]
 UniProt Related Accession #    P25713 [Other Products]
 Molecular Weight    6,927 Da
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 NCBI Official Full Name    metallothionein-3
 NCBI Official Synonym Full Names    metallothionein 3
 NCBI Official Symbol    MT3 [Similar Products]
 NCBI Official Synonym Symbols   
GIF; GIFB; GRIF; ZnMT3
[Similar Products]
 NCBI Protein Information    metallothionein-3; MT-3; MT-III; metallothionein-III; growth inhibitory factor; metallothionein 3 (growth inhibitory factor (neurotrophic))
 UniProt Protein Name    Metallothionein-3
 UniProt Synonym Protein Names   
GIFB; GIF; Growth inhibitory factor; Metallothionein-III; MT-III
 Protein Family    Metallothionein
 UniProt Gene Name    MT3 [Similar Products]
 UniProt Synonym Gene Names    MT-3; GIF; MT-III [Similar Products]
 UniProt Entry Name    MT3_HUMAN
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 UniProt Comments for MT3    MT3: Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro. Belongs to the metallothionein superfamily. Type 1 family.

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: synaptic vesicle; perinuclear region of cytoplasm; cytoplasm; intracellular; inclusion body

Molecular Function: antioxidant activity; protein binding; copper ion binding; zinc ion binding; caspase inhibitor activity; drug binding; cadmium ion binding; protein kinase activator activity

Biological Process: positive regulation of catalytic activity; negative regulation of autophagy; removal of superoxide radicals; positive regulation of transcription, DNA-dependent; negative regulation of axon extension; negative regulation of caspase activity; positive regulation of vascular endothelial growth factor receptor signaling pathway; zinc ion homeostasis; cadmium ion homeostasis; cellular lipid catabolic process; histone modification; protein kinase B signaling cascade; negative regulation of neuron apoptosis; cholesterol catabolic process; regulation of response to food; protein stabilization; activation of protein kinase B; cellular zinc ion homeostasis; zinc ion transport; regulation of protein amino acid glycosylation; leptin-mediated signaling pathway; astrocyte development; cell proliferation; cellular metal ion homeostasis; protein import into nucleus, translocation; negative regulation of oxidoreductase activity; response to hypoxia; energy reserve metabolic process; positive regulation of protein amino acid phosphorylation; negative regulation of cell growth; negative regulation of transcription, DNA-dependent; negative regulation of apoptosis
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 Research Articles on MT3    1. MT-capital I, Ukrainiancapital I, Ukrainiancapital I, Ukrainian increases the amount of active ADAM10 in association with furin, PC7 and PKCalpha.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MT3 recombinant proteinDiseases associated with MT3 recombinant protein
 Reference Product  PubMed Publications
 CD4 recombinant protein  >1 publications with MT3 and CD4
 TTR recombinant protein  >1 publications with MT3 and TTR
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >26 publications with MT3 and Immune System Diseases
 Nervous System Diseases Antibodies  >25 publications with MT3 and Nervous System Diseases
 Neoplasm Metastasis Antibodies  >20 publications with MT3 and Neoplasm Metastasis
 Brain Diseases Antibodies  >15 publications with MT3 and Brain Diseases
 Breast Neoplasms Antibodies  >12 publications with MT3 and Breast Neoplasms
 Cardiovascular Diseases Antibodies  >11 publications with MT3 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >11 publications with MT3 and Disease Models, Animal
 Inflammation Antibodies  >10 publications with MT3 and Inflammation
 Lung Diseases Antibodies  >9 publications with MT3 and Lung Diseases
 Lung Neoplasms Antibodies  >9 publications with MT3 and Lung Neoplasms
Organs/Tissues associated with MT3 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >65 publications with MT3 and Brain
 Connective Tissue Antibodies  >12 publications with MT3 and Connective Tissue
 Eye Antibodies  >12 publications with MT3 and Eye
 Ovary Antibodies  >8 publications with MT3 and Ovary
 Prostate Antibodies  >8 publications with MT3 and Prostate
 Spinal Cord Antibodies  >4 publications with MT3 and Spinal Cord
 Testis Antibodies  >1 publications with MT3 and Testis
 Adrenal Gland Antibodies  >1 publications with MT3 and Adrenal Gland
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