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MAP2 recombinant protein :: Microtubule Associated Protein 2 (MAP2) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2012357 (3 units are in stock [0.1 mg] for immediate shipment)
Unit / Price
0.01 mg  /  $140 +1 FREE 8GB USB
0.05 mg  /  $260 +1 FREE 8GB USB
0.1 mg  /  $400 +1 FREE 8GB USB
0.2 mg  /  $495 +1 FREE 8GB USB
0.5 mg  /  $955 +1 FREE 8GB USB
1 mg  /  $1,415 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Microtubule Associated Protein 2 (MAP2), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Microtubule Associated Protein 2 (MAP2)

 Product Gene Name   

MAP2 recombinant protein

[Similar Products]
 Matching Pairs    Antibody: Microtubule Associated Protein 2 (MAP2) (MBS2003826)
Antigen: Microtubule Associated Protein 2 (MAP2) (MBS2012357)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 2; NC_000002.11 (210288733..210598842). Location: 2q34-q35
 OMIM    157130
 3D Structure    ModBase 3D Structure for P11137
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 Host    E. coli
 Species Reactivity    Human
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 Purity/Purification    >98%
 Form/Format    10mM PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and Proclin300.
 Concentration    200ug/mL (lot specific)
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 Source    Prokaryotic expression
 Residues    Leu727~Asp985
 Tags    N-terminal His-Tag
 Tissue Specificity    Brain, Pancreas, Uterus
 Subcellular Location    Cytoplasm, cytoskeleton
 Traits    Freeze-dried powder
    
 Predicted isoelectric point    4.7
 Predicted Molecular Mass    29.4kDa
 Accurate Molecular Mass    43kDa as determined by SDS-PAGE reducing conditions
 Usage    Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8 degree C for one month.
Aliquot and store at -80 degree C for two years.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of MAP2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for MAP2 recombinant protein   

SDS-PAGE, WB, ELISA, IP, CoIP, Purification, Amine Reactive Labeling.

(May be suitable for use in other assays to be determined by the end user.)

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 Sequence of MAP2 recombinant protein    MAP2 recombinant protein Sequence image
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 Gene Sequencing (extract) of MAP2 recombinant protein    MAP2 recombinant protein Gene Sequencing (extract) image
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 SDS-PAGE of MAP2 recombinant protein    MAP2 recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for MAP2. It may not necessarily be applicable to this product.
 NCBI GI #    87578394
 NCBI GeneID    4133
 NCBI Accession #    NP_001034627.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001039538.1 [Other Products]
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 UniProt Primary Accession #    P11137 [Other Products]
 UniProt Secondary Accession #    Q17S04; Q8IUX2; Q99975; Q99976 [Other Products]
 UniProt Related Accession #    P11137 [Other Products]
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 NCBI Official Full Name    microtubule-associated protein 2 isoform 5
 NCBI Official Synonym Full Names    microtubule-associated protein 2
 NCBI Official Symbol    MAP2 [Similar Products]
 NCBI Official Synonym Symbols   
MAP2A; MAP2B; MAP2C
[Similar Products]
 NCBI Protein Information    microtubule-associated protein 2; MAP-2
 UniProt Protein Name    Microtubule-associated protein 2
 Protein Family    Microtubule-associated protein
 UniProt Gene Name    MAP2 [Similar Products]
 UniProt Synonym Gene Names    MAP-2 [Similar Products]
 UniProt Entry Name    MTAP2_HUMAN
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 NCBI Summary for MAP2    This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]
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 UniProt Comments for MAP2    MAP2: a member of the microtubule-associated protein (MAP) family. Its exact function is unknown but MAPs appear to stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. Expressed at high levels in neural tissue and the prostate. Four alternatively spliced transcript variants have been reported.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 2q34-q35

Cellular Component: microtubule; microtubule associated complex; cell soma; cytoplasm; nucleolus; dendritic shaft

Molecular Function: calmodulin binding; protein binding; microtubule binding; structural molecule activity

Biological Process: axonogenesis; dendrite morphogenesis; microtubule bundle formation; neurite development; central nervous system neuron development
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 Research Articles on MAP2    1. MAP-2 and nestin participate in the regulation of the development of gastric tissues in human embryos.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MAP2 recombinant proteinPathways associated with MAP2 recombinant protein
 Reference Product  PubMed Publications
 MBP recombinant protein  >30 publications with MAP2 and MBP
 MAPK1 recombinant protein  >10 publications with MAP2 and MAPK1
 SRC recombinant protein  >8 publications with MAP2 and SRC
 FYN recombinant protein  >7 publications with MAP2 and FYN
 GRB2 recombinant protein  >2 publications with MAP2 and GRB2
 Products by Pathway  Pathway Diagram
 LKB1 Signaling Events Pathway antibodies  LKB1 Signaling Events Pathway Diagram
 MAPK Cascade Pathway antibodies  MAPK Cascade Pathway Diagram
 SIDS Susceptibility Pathways antibodies  SIDS Susceptibility Pathways Diagram
Diseases associated with MAP2 recombinant proteinOrgans/Tissues associated with MAP2 recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >480 publications with MAP2 and Nervous System Diseases
 Brain Diseases Antibodies  >415 publications with MAP2 and Brain Diseases
 Neoplasms Antibodies  >168 publications with MAP2 and Neoplasms
 Cardiovascular Diseases Antibodies  >143 publications with MAP2 and Cardiovascular Diseases
 Nerve Degeneration Antibodies  >68 publications with MAP2 and Nerve Degeneration
 Movement Disorders Antibodies  >39 publications with MAP2 and Movement Disorders
 Inflammation Antibodies  >31 publications with MAP2 and Inflammation
 Necrosis Antibodies  >31 publications with MAP2 and Necrosis
 Atrophy Antibodies  >26 publications with MAP2 and Atrophy
 Immune System Diseases Antibodies  >25 publications with MAP2 and Immune System Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1335 publications with MAP2 and Brain
 Nerve Antibodies  >527 publications with MAP2 and Nerve
 Embryonic Tissue Antibodies  >140 publications with MAP2 and Embryonic Tissue
 Bone Antibodies  >65 publications with MAP2 and Bone
 Eye Antibodies  >54 publications with MAP2 and Eye
 Muscle Antibodies  >43 publications with MAP2 and Muscle
 Vascular Antibodies  >43 publications with MAP2 and Vascular
 Liver Antibodies  >23 publications with MAP2 and Liver
 Adrenal Gland Antibodies  >22 publications with MAP2 and Adrenal Gland
 Connective Tissue Antibodies  >20 publications with MAP2 and Connective Tissue
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