Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow TAU  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Reticulocalbin 2 (RCN2) ELISA Kit
 • LGALS3 cDNA Clone
 • Phenytoin Protein
 • (Rhesus macaque) Growth hormone receptor (GHR) Recombinant Protein
 • Urokinase plasminogen activator surface receptor (Plau) Antibody
 • C-type lectin domain family 16, member A (CLEC16A) ELISA Kit
 • Parvalbumin a (PALB a) ELISA Kit
 • UBC13 (UBE2N) Antibody
 • MannoseReceptor (MR) ELISA Kit
 • GARS Antibody
 • Microtubule Associated Protein 1 Light Chain 3 Alpha (MAP1LC... ELISA Kit
 • MAP10 Antibody
 • Ovalbumin (SERPINB14) Antibody
 • Gentamicin Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

TAU recombinant protein :: Microtubule-associated protein tau Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS9422386 TAU recombinant protein
Unit / Price
0.01 mg  /  $230 +1 FREE 8GB USB
0.05 mg  /  $290 +1 FREE 8GB USB
0.1 mg  /  $455 +1 FREE 8GB USB
0.2 mg  /  $705 +1 FREE 8GB USB
0.5 mg  /  $1,145 +1 FREE 8GB USB
1 mg  /  $1,800 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Microtubule-associated protein tau, Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Rat Microtubule-associated protein tau

 Product Synonym Names    Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau
 Product Gene Name   

TAU recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence Positions    Full Length, 2-752aa
 Sequence    AEPRQEFDTM EDQAGDYTML QDQEGDMDHG LKESPPQPPA DDGSEEPGSE TSDAKSTPTA EDVTAPLVEE RAPDKQATAQ SHTEIPEGTT AEEAGIGDTP NMEDQAAGHV TQEPQKVEIF SQSLLVEPGR REGQAPDSGI SDWTHQQVPS MSGAPLPPQG LREATHQPLG TRPEDVERSH PASELLWQES PQKEAWGKDR LGSEEEVDED ITMDESSQES PPSQASLAPG TATPQARSVS ASGVSGETTS IPGFPAEGSI PLPADFFSKV SAETQASPPE GPGTGPSEEG HEAAPEFTFH VEIKASAPKE QDLEGATVVG APAEEQKARG PSVGKGTKEA SLLEPTDKQP AAGLPGRPVS RVPQLKARVA GVSKDRTGND EKKAKTSTPS CAKTPSNRPC LSPTRPTPGS SDPLIKPSSP AVCPEPATSP KYVSSVTPRN GSPGTKQMKL KGADGKTGAK IATPRGAATP GQKGTSNATR IPAKTTPSPK TPPGSGEPPK SGERSGYSSP GSPGTPGSRS RTPSLPTPPT REPKKVAVVR TPPKSPSASK SRLQTAPVPM PDLKNVRSKI GSTENLKHQP GGGKVQIINK KLDLSNVQSK CGSKDNIKHV PGGGSVHIVY KPVDLSKVTS KCGSLGNIHH KPGGGQVEVK SEKLDFKDRV QSKIGSLDNI THVPGGGNKK IETHKLTFRE NAKAKTDHGA EIVYKSPVVS GDTSPRHLSN VSSTGSIDMV DSPQLATLAD EVSASLAKQG L
 3D Structure    ModBase 3D Structure for P19332
Section Bar
 Host    Yeast
 Species Reactivity    Rat
Section Bar
 Purity/Purification    Greater than 90% as determined by SDS-PAGE.
 Form/Format    20mM Tris-HCl based buffer, pH8.0
Section Bar
 Tag Info    His-tag
Section Bar
 Preparation and Storage    Store at -20C, for extended storage, conserve at -20C or -80C. Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
 Other Notes    Small volumes of TAU recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for TAU recombinant protein

   Promotes microtubule assbly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma mbrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
NCBI/Uniprot data below describe general gene information for TAU. It may not necessarily be applicable to this product.
 NCBI GI #    13432197
 NCBI GeneID    29477
 NCBI Accession #    P19332.3 [Other Products]
Section Bar
 UniProt Primary Accession #    P19332 [Other Products]
 UniProt Secondary Accession #    Q63567; Q63677; Q9QW06 [Other Products]
 UniProt Related Accession #    P19332 [Other Products]
 Molecular Weight    80.4kD
Table BarTOPTable Bar
 NCBI Official Full Name    Microtubule-associated protein tau
 NCBI Official Synonym Full Names    microtubule-associated protein tau
 NCBI Official Symbol    Mapt [Similar Products]
 NCBI Official Synonym Symbols   
Tau; pTau; Mtapt; RNPTAU
[Similar Products]
 NCBI Protein Information    microtubule-associated protein tau
 UniProt Protein Name    Microtubule-associated protein tau
 UniProt Synonym Protein Names   
Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau
 Protein Family    Microtubule-associated protein
 UniProt Gene Name    Mapt [Similar Products]
 UniProt Synonym Gene Names    Mtapt; Tau; PHF-tau [Similar Products]
Section Bar
 NCBI Summary for TAU    a microtubule-associated protein; expression is found specifically in neurons [RGD, Feb 2006]
Section Bar
 UniProt Comments for TAU    Tau: a microtubule-associated protein that regulates microtubule assembly and stability. Apparently involved in the establishment and maintenance of neuronal polarity. Mutations can result in several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. Nine differentially spliced isoforms have been described. The short isoforms allow plasticity of the cytoskeleton, whereas the longer isoforms may preferentially play a role in its stabilization.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 10q32.1

Cellular Component: axolemma; axon; axoneme; cell soma; cytoplasm; cytosol; dendrite; growth cone; internal side of plasma membrane; membrane; microtubule; microtubule associated complex; microtubule cytoskeleton; neuron projection; nuclear speck; nucleus; plasma membrane; postsynaptic density; tubulin complex

Molecular Function: apolipoprotein binding; DNA binding; enzyme binding; Hsp90 protein binding; identical protein binding; microtubule binding; protein binding; protein complex binding; protein domain specific binding; protein homodimerization activity; protein kinase binding; protein phosphatase 2A binding; receptor agonist activity; SH3 domain binding

Biological Process: adult walking behavior; apoptosis; axon cargo transport; axon extension; axonogenesis; brain development; female pregnancy; induction of apoptosis by oxidative stress; intracellular distribution of mitochondria; memory; microtubule cytoskeleton organization and biogenesis; mitochondrion transport along microtubule; negative regulation of intracellular transport; negative regulation of kinase activity; neurite development; neuron migration; positive regulation of axon extension; positive regulation of microtubule polymerization; positive regulation of superoxide release; regulation of autophagy; regulation of calcium-mediated signaling; regulation of microtubule polymerization or depolymerization; response to nutrient; response to organic substance; synapse organization and biogenesis
Table BarTOPTable Bar
 Research Articles on TAU    1. analysis of MAP2c phosphorylation and regulatory protein 14-3-3zeta-binding sites, which reveals key differences between MAP2c and its homolog Tau
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with TAU recombinant proteinOrgans/Tissues associated with TAU recombinant protein
 Products by Pathway  Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptotic Cleavage Of Cellular Proteins Pathway antibodies  Apoptotic Cleavage Of Cellular Proteins Pathway Diagram
 Apoptotic Execution Phase Pathway antibodies  Apoptotic Execution Phase Pathway Diagram
 Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway antibodies  Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Programmed Cell Death Pathway antibodies  Programmed Cell Death Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >756 publications with TAU and Brain
 Nerve Antibodies  >241 publications with TAU and Nerve
 Eye Antibodies  >16 publications with TAU and Eye
 Embryonic Tissue Antibodies  >10 publications with TAU and Embryonic Tissue
 Heart Antibodies  >9 publications with TAU and Heart
 Kidney Antibodies  >6 publications with TAU and Kidney
 Dorsal Root Ganglion Antibodies  >4 publications with TAU and Dorsal Root Ganglion
 Prostate Antibodies  >3 publications with TAU and Prostate
 Lung Antibodies  >2 publications with TAU and Lung
 Testis Antibodies  >1 publications with TAU and Testis
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions