Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow SLC25A11  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • ORC1L Antibody
 • Turkey IgG Immunoglobulin
 • CD18 Antibody
 • zyxin Antibody
 • prorenin-renin antiserum Antibody
 • Growth Factor Receptor Bound Protein 2 (Grb2) ELISA Kit
 • Motilin (MTL) ELISA Kit
 • glucagon like peptide 1 (GLP1) ELISA Kit
 • Beta-2-glycoprotein 1 (APOH) Recombinant Protein
 • Asymmetric Dimethylaoyoinine (ADMA) ELISA Kit
 • Cotinine ELISA Kit
 • Sulphaquinoxaline HRP Conjugate
 • Angiotensin 2 Receptor 1 Antibody (AT2R1) ELISA Kit
 • Mouse IgG2a Isotype Control Control & Calibrator
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

SLC25A11 recombinant protein :: Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS965743 SLC25A11 recombinant protein
Unit / Price
 Please Inquire 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11), Recombinant Protein

 Also Known As   

Recombinant Human Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11)

 Product Gene Name   

SLC25A11 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Recombinant Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11); Mitochondrial 2-oxoglutarate/malate carrier protein; OGCP; Solute carrier family 25 member 11 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence Positions    2-314
 Sequence    AATASAGAGG IDGKPRTSPK SVKFLFGGLA GMGATVFVQP LDLVKNRMQL SGEGAKTREY KTSFHALTSI LKAEGLRGIY TGLSAGLLRQ ATYTTTRLGI YTVLFERLTG ADGTPPGFLL KAVIGMTAGA TGAFVGTPAE VALIRMTADG RLPADQRRGY KNVFNALIRI TREEGVLTLW RGCIPTMARA VVVNAAQLAS YSQSKQFLLD SGYFSDNILC HFCASMISGL VTTAASMPVD IAKTRIQNMR MIDGKPEYKN GLDVLFKVVR YEGFFSLWKG FTPYYARLGP HTVLTFIFLE QMNKAYKRLF LSG
 Chromosome Location    Chromosome: 17; NC_000017.10 (4840425..4843462, complement). Location: 17p13.3
 OMIM    604165
 3D Structure    ModBase 3D Structure for Q02978
Section Bar
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
Section Bar
 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
Section Bar
 Species    Homo sapiens (Human)
Section Bar
 Preparation and Storage    Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of SLC25A11 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for SLC25A11 recombinant protein

   SLC25A11; SLC20A4
NCBI/Uniprot data below describe general gene information for SLC25A11. It may not necessarily be applicable to this product.
 NCBI GI #    21361114
 NCBI GeneID    8402
 NCBI Accession #    NP_003553.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_003562.4 [Other Products]
Section Bar
 UniProt Primary Accession #    Q02978 [Other Products]
 UniProt Secondary Accession #    O75537; Q969P7 [Other Products]
 UniProt Related Accession #    Q02978 [Other Products]
 Molecular Weight    34,062 Da [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    mitochondrial 2-oxoglutarate/malate carrier protein isoform 1
 NCBI Official Synonym Full Names    solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
 NCBI Official Symbol    SLC25A11 [Similar Products]
 NCBI Official Synonym Symbols   
OGC; SLC20A4
[Similar Products]
 NCBI Protein Information    mitochondrial 2-oxoglutarate/malate carrier protein; OGCP; solute carrier family 25 member 11; solute carrier family 20 (oxoglutarate carrier), member 4
 UniProt Protein Name    Mitochondrial 2-oxoglutarate/malate carrier protein
 UniProt Synonym Protein Names   
Solute carrier family 25 member 11
 Protein Family    Mitochondrial 2-oxoglutarate/malate carrier protein
 UniProt Gene Name    SLC25A11 [Similar Products]
 UniProt Synonym Gene Names    SLC20A4; OGCP [Similar Products]
 UniProt Entry Name    M2OM_HUMAN
Section Bar
 NCBI Summary for SLC25A11    The oxoglutarate/malate carrier transports 2-oxoglutarate across the inner membranes of mitochondria in an electroneutral exchange for malate or other dicarboxylic acids (summary by Iacobazzi et al., 1992 [PubMed 1457818]).[supplied by OMIM, Jan 2011]
Section Bar
 UniProt Comments for SLC25A11    SLC25A11: Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism. Belongs to the mitochondrial carrier family.

Protein type: Membrane protein, multi-pass; Mitochondrial; Transporter; Transporter, SLC family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: mitochondrion; integral to plasma membrane; mitochondrial inner membrane; nucleus

Molecular Function: oxoglutarate:malate antiporter activity

Biological Process: transport; alpha-ketoglutarate transport; carbohydrate metabolic process; glucose metabolic process; pathogenesis; gluconeogenesis
Table BarTOPTable Bar
 Research Articles on SLC25A11    1. OGCP degrades through proteasome and lysosome degradation pathways. The degradation of parkin protein can promote the degradation of OGCP.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with SLC25A11 recombinant proteinDiseases associated with SLC25A11 recombinant protein
 Products by Pathway  Pathway Diagram
 Gluconeogenesis Pathway antibodies  Gluconeogenesis Pathway Diagram
 Glucose Metabolism Pathway antibodies  Glucose Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >2 publications with SLC25A11 and Liver Diseases
 Mental Disorders Antibodies  >1 publications with SLC25A11 and Mental Disorders
 Disease Models, Animal Antibodies  >1 publications with SLC25A11 and Disease Models, Animal
 Neoplasms Antibodies  >1 publications with SLC25A11 and Neoplasms
 Liver Cirrhosis Antibodies  >1 publications with SLC25A11 and Liver Cirrhosis
 Neoplasms, Experimental Antibodies  >1 publications with SLC25A11 and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >1 publications with SLC25A11 and Liver Neoplasms
 Liver Neoplasms, Experimental Antibodies  >1 publications with SLC25A11 and Liver Neoplasms, Experimental
 Kidney Diseases Antibodies  >1 publications with SLC25A11 and Kidney Diseases
Organs/Tissues associated with SLC25A11 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >2 publications with SLC25A11 and Kidney
 Liver Antibodies  >2 publications with SLC25A11 and Liver
 Heart Antibodies  >1 publications with SLC25A11 and Heart
 Muscle Antibodies  >1 publications with SLC25A11 and Muscle
 Blood Antibodies  >1 publications with SLC25A11 and Blood
 Brain Antibodies  >1 publications with SLC25A11 and Brain
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions