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UCP1 recombinant protein :: Mitochondrial brown fat uncoupling protein 1 (UCP1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS965372 UCP1 recombinant protein
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Mitochondrial brown fat uncoupling protein 1 (UCP1), Recombinant Protein

 Also Known As   

Recombinant Bovine Mitochondrial brown fat uncoupling protein 1 (UCP1)

 Product Synonym Names    Recombinant Mitochondrial brown fat uncoupling protein 1 (UCP1); Mitochondrial brown fat uncoupling protein 1; UCP 1; Solute carrier family 25 member 7 Thermogenin
 Product Gene Name   

UCP1 recombinant protein

[Similar Products]
 Product Synonym Gene Name    UCP1; SLC25A7, UCP [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-288
 Sequence    IFSAGVAACV ADIITFPLDT AKVRLQIQGE CLISSAIRYK GVLGTIITLA KTEGPVKLYS GLPAGLQRQI SLASLRIGLY DTVQEFFTTG KEASLGSKIS AGLMTGGVAV FIGQPTEVVK VRLQAQSHLH GPKPRYTGTY NAYRIIATTE GLTGLWKGTS PNLTTNVIIN CTELVTYDLM KEALVKNKLL ADDVPCHFVS AVVAGFCTTV LSSPVDVVKT RFVNSSPGQN TSVPNCAMMM LTREGPSAFF KGFVPSFLRL GSWNIMFVCF ERLKQELMKC RHTMDCAT
 Chromosome Location    Chromosome: 17; AC_000174.1 (17467450..17473934). Location: chromosome: 17
 3D Structure    ModBase 3D Structure for P10861
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Bos taurus (Bovine)
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 Preparation and Storage    Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of UCP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for UCP1. It may not necessarily be applicable to this product.
 NCBI GI #    1717948
 NCBI GeneID    281561
 NCBI Accession #    P10861.2 [Other Products]
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 UniProt Primary Accession #    P10861 [Other Products]
 UniProt Related Accession #    P10861 [Other Products]
 Molecular Weight    31,143 Da [Similar Products]
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 NCBI Official Full Name    Mitochondrial brown fat uncoupling protein 1
 NCBI Official Synonym Full Names    uncoupling protein 1 (mitochondrial, proton carrier)<
 NCBI Official Symbol    UCP1 [Similar Products]
 NCBI Protein Information    mitochondrial brown fat uncoupling protein 1; UCP 1; thermogenin; mitochondrial, proton carrier; solute carrier family 25 member 7
 UniProt Protein Name    Mitochondrial brown fat uncoupling protein 1
 UniProt Synonym Protein Names   
Solute carrier family 25 member 7; Thermogenin
 Protein Family    Mitochondrial brown fat uncoupling protein
 UniProt Gene Name    UCP1 [Similar Products]
 UniProt Synonym Gene Names    SLC25A7; UCP; UCP 1 [Similar Products]
 UniProt Entry Name    UCP1_BOVIN
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 UniProt Comments for UCP1    Function: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.

Subunit structure: Acts as a dimer forming a proton channel.

Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein.

Tissue specificity: Brown adipose tissue.

Sequence similarities: Belongs to the mitochondrial carrier family.Contains 3 Solcar repeats.
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 Research Articles on UCP1    1. These results suggest that CIDE-A and UCP1 are regulated by insulin and/or fatty acids in mammary epithelial cells and lactating mammary glands, and thereby play an important role in lipid and energy metabolism.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with UCP1 recombinant proteinOrgans/Tissues associated with UCP1 recombinant protein
 Products by Pathway  Pathway Diagram
 Electron Transport Chain Pathway antibodies  Electron Transport Chain Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Mitochondrial Uncoupling Proteins Pathway antibodies  Mitochondrial Uncoupling Proteins Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 Respiratory Electron Transport, ATP Synthesis By Chemiosmotic Coupling, And Heat Production By Uncoupling Proteins. Pathway antibodies  Respiratory Electron Transport, ATP Synthesis By Chemiosmotic Coupling, And Heat Production By Uncoupling Proteins. Pathway Diagram
 The Citric Acid (TCA) Cycle And Respiratory Electron Transport Pathway antibodies  The Citric Acid (TCA) Cycle And Respiratory Electron Transport Pathway Diagram
 The Fatty Acid Cycling Model Pathway antibodies  The Fatty Acid Cycling Model Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >7 publications with UCP1 and Mixed
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