NP_001081096.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
24,389 Da
NCBI Official Full Name
mitotic spindle assembly checkpoint protein MAD2B
NCBI Official Synonym Full Names
mitotic arrest deficient 2 like 2 S homeolog
NCBI Official Synonym Symbols
mad2B; mad2l2; xMAD2L2; mad2l2-A [Similar Products]
NCBI Protein Information
mitotic spindle assembly checkpoint protein MAD2B
UniProt Protein Name
Mitotic spindle assembly checkpoint protein MAD2B
UniProt Synonym Protein Names
Mad2l2-A protein; Mitotic arrest defective protein 2B; Mitotic arrest deficient 2-like protein 2; MAD2-like protein 2; xMAD2L2
UniProt Synonym Gene Names
UniProt Comments for mad2l2
Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit rev3l and the inserter polymerase rev1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also play a role in signal transduction in response to DNA damage. May regulate the activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Through transcriptional regulation may play a role in epithelial-mesenchymal transdifferentiation.
Research Articles on mad2l2
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Pathways associated with mad2l2 recombinant protein
Diseases associated with mad2l2 recombinant protein
Organs/Tissues associated with mad2l2 recombinant protein
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