NP_001291288.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
33.6 kDa
NCBI Official Full Name
mucin-5AC
NCBI Official Synonym Full Names
mucin 5AC, oligomeric mucus/gel-forming
NCBI Protein Information
mucin-5AC
UniProt Protein Name
Mucin-5AC
UniProt Synonym Protein Names
Gastric mucin
UniProt Synonym Gene Names
UniProt Entry Name
MUC5A_HUMAN
UniProt Comments for Muc5ac
MUC5AC iso1:
Chromosomal Location of Human Ortholog: 11p15.5
Cellular Component: cytoplasm; extracellular space; fibril; Golgi lumen
Molecular Function: extracellular matrix structural constituent
Biological Process: cellular protein metabolic process; fibril organization and biogenesis; O-glycan processing; phosphoinositide-mediated signaling; post-translational protein modification; protein amino acid O-linked glycosylation
Product References and Citations for Muc5ac recombinant protein
Human chromosome 11 DNA sequence and analysis including novel gene identification.Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G., Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y.Nature 440:497-500(2006)
Human mucin gene MUC5AC
organization of its 5'-region and central repetitive region.Escande F., Aubert J.-P., Porchet N., Buisine M.P.Biochem. J. 358:763-772(2001)
Cloning of the amino-terminal and 5'-flanking region of the human MUC5AC mucin gene and transcriptional up-regulation by bacterial exoproducts.Li D., Gallup M., Fan N., Szymkowski D.E., Basbaum C.B.J. Biol. Chem. 273:6812-6820(1998)
Cloning and analysis of human gastric mucin cDNA reveals two types of conserved cysteine-rich domains.Klomp L.W., Van Rens L., Strous G.J.Biochem. J. 308:831-838(1995)
Proteolytic fragmentation and peptide mapping of human carboxyamidomethylated tracheobronchial mucin.Rose M.C., Kaufman B., Martin B.M.J. Biol. Chem. 264:8193-8199(1989)
Genomic organization of the 3'-region of the human MUC5AC mucin gene
additional evidence for a common ancestral gene for the 11p15.5 mucin gene family.Buisine M.P., Desseyn J.-L., Porchet N., Degand P., Laine A., Aubert J.-P.Biochem. J. 332:729-738(1998)
Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5)
.Meerzaman D., Charles P., Daskal E., Polymeropoulos M.H., Martin B.M., Rose M.C.J. Biol. Chem. 269:12932-12939(1994)
Characterization of a mucin cDNA clone isolated from HT-29 mucus secreting cells
the 3' end of MUC5AC?Lesuffleur T., Roche F., Hill A.S., Lacasa M., Fox M., Swallow D.M., Zweibaum A., Real F.X.J. Biol. Chem. 270:13665-13673(1995)
Cleavage in the GDPH sequence of the C-terminal cysteine-rich part of the human MUC5AC mucin.Lidell M.E., Hansson G.C.Biochem. J. 399:121-129(2006)
The full-ORF clone resource of the German cDNA consortium.Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I.BMC Genomics 8:399-399(2007)
In vivo glycosylation of mucin tandem repeats.Silverman H.S., Parry S., Sutton-Smith M., Burdick M.D., McDermott K., Reid C.J., Batra S.K., Morris H.R., Hollingsworth M.A., Dell A., Harris A.Glycobiology 11:459-471(2001)
The MUC5AC glycoprotein is the primary receptor for Helicobacter pylori in the human stomach.Van de Bovenkamp J.H., Mahdavi J., Korteland-Van Male A.M., Bueller H.A., Einerhand A.W., Boren T., Dekker J.Helicobacter 8:521-532(2003)
C-Mannosylation of MUC5AC and MUC5B Cys subdomains.Perez-Vilar J., Randell S.H., Boucher R.C.Glycobiology 14:325-337(2004)
Research Articles on Muc5ac
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Pathways associated with Muc5ac recombinant protein
Diseases associated with Muc5ac recombinant protein
Organs/Tissues associated with Muc5ac recombinant protein
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