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MUG1 recombinant protein :: Murinoglobulin-1 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS9420926 MUG1 recombinant protein
Unit / Price
0.01 mg  /  $230 +1 FREE 8GB USB
0.05 mg  /  $290 +1 FREE 8GB USB
0.1 mg  /  $455 +1 FREE 8GB USB
0.2 mg  /  $710 +1 FREE 8GB USB
0.5 mg  /  $1,145 +1 FREE 8GB USB
1 mg  /  $1,795 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Murinoglobulin-1 (MUG1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant mouse Murinoglobulin-1

 Product Gene Name   

MUG1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    Partial, 700-910aa
 Sequence    TPEISWSLRT TLSKRPEEPP RKDPSSNDPL TETIRKYFPE TWVWDIVTVN STGLAEVEMT VPDTITEWKA GALC LSND TGLGLSSVVP LQAFKPFFVE VSLPYSVVRG EAFMLKATVM NYLPTSMQMS VQLEASPDFT AVPVGDDQ DSYCLSANGR HTSSWLVTPK SLGNVNFSVS AEAQQSSEPC GSEVATVPET GRKDTVVKVL IVEPE
 3D Structure    ModBase 3D Structure for P28665
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 Host    E Coli
 Species Reactivity    Mouse
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE.
 Form/Format    20mM Tris-HCl based buffer, pH8.0
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 Brief Description    Recombinant Protein
 Tag Info    His-tag
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 Preparation and Storage    Store at -20C, for extended storage, conserve at -20C or -80C. Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
 Other Notes    Small volumes of MUG1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for MUG1 recombinant protein

   A proteinase activates the inhibitor by specific proteolysis in the bait region, which, by an unknown mechanism leads to reaction at the cysteinyl-glutamyl internal thiol ester site and to a conformational change, whereby the proteinase is trapped and/or covalently bound to the inhibitor. While in the tetrameric proteinase inhibitors steric inhibition is sufficiently strong, monomeric forms need a covalent linkage between the activated glutamyl residue of the original thiol ester and a terminal amino group of a lysine or another nucleophilic group on the proteinase, for inhibition to be effective.
NCBI/Uniprot data below describe general gene information for MUG1. It may not necessarily be applicable to this product.
 NCBI GI #    31982171
 NCBI GeneID    17836
 NCBI Accession #    NP_032671.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_008645.3 [Other Products]
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 UniProt Primary Accession #    P28665 [Other Products]
 UniProt Secondary Accession #    Q3UNE7; Q80XE6 [Other Products]
 UniProt Related Accession #    P28665 [Other Products]
 Molecular Weight    27.13kD
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 NCBI Official Full Name    murinoglobulin-1
 NCBI Official Synonym Full Names    murinoglobulin 1
 NCBI Official Symbol    Mug1 [Similar Products]
 NCBI Protein Information    murinoglobulin-1
 UniProt Protein Name    Murinoglobulin-1
 Protein Family    Murinoglobulin
 UniProt Gene Name    Mug1 [Similar Products]
 UniProt Synonym Gene Names    Mug-1; MuG1 [Similar Products]
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 UniProt Comments for MUG1    Mug1: A proteinase activates the inhibitor by specific proteolysis in the bait region, which, by an unknown mechanism leads to reaction at the cysteinyl-glutamyl internal thiol ester site and to a conformational change, whereby the proteinase is trapped and/or covalently bound to the inhibitor. While in the tetrameric proteinase inhibitors steric inhibition is sufficiently strong, monomeric forms need a covalent linkage between the activated glutamyl residue of the original thiol ester and a terminal amino group of a lysine or another nucleophilic group on the proteinase, for inhibition to be effective. Belongs to the protease inhibitor I39 (alpha-2- macroglobulin) family.

Chromosomal Location of Human Ortholog: 6|6 F1

Biological Process: embryo implantation
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 Research Articles on MUG1    1. susceptibility to T. cruzi infection of mice that are deficient only in alpha2-macroglobulins (AM-KO) or in both MAM and monomeric murinoglobulin-1 (MM-KO), relative to the wild type (WT)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with MUG1 recombinant proteinOrgans/Tissues associated with MUG1 recombinant protein
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >1 publications with MUG1 and Disease Models, Animal
 Necrosis Antibodies  >1 publications with MUG1 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1 publications with MUG1 and Liver
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