NP_001018100.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
Molecular Weight
64,046 Da
NCBI Official Full Name
GRINL1A combined protein isoform 1
NCBI Official Synonym Full Names
GRINL1A complex locus 1
NCBI Official Synonym Symbols
gcom; Gcom2; MYZAP; GRINL1A; MYZAP-POLR2M [Similar Products]
NCBI Protein Information
GRINL1A combined protein
UniProt Protein Name
Myocardial zonula adherens protein
UniProt Synonym Protein Names
GRINL1A upstream protein; Gup
UniProt Synonym Gene Names
NCBI Summary for MYZAP
This locus represents naturally occurring readthrough transcription between the neighboring MYZAP (myocardial zonula adherens protein) and POLR2M (polymerase (RNA) II (DNA directed) polypeptide M) genes on chromosome 15. Alternative splicing results in multiple readthrough transcript variants. Readthrough variants may encode proteins that share sequence identity with the upstream gene product or with both the upstream and downstream gene products. Some readthrough transcript variants are also expected to be candidates for nonsense-mediated decay (NMD). [provided by RefSeq, Oct 2013]
UniProt Comments for MYZAP
Plays a role in cellular signaling via Rho-related GTP-binding proteins and subsequent activation of transcription factor SRF (). Targets TJP1 to cell junctions. In cortical neurons, may play a role in glutaminergic signal transduction through interaction with the NMDA receptor subunit GRIN1 ().
Research Articles on MYZAP
Precautions
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Disclaimer
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Organs/Tissues associated with MYZAP recombinant protein
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