NP_001039578.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
47,844 Da
NCBI Official Full Name
myocyte-specific enhancer factor 2C
NCBI Official Synonym Full Names
myocyte enhancer factor 2C
NCBI Protein Information
myocyte-specific enhancer factor 2C
UniProt Protein Name
Myocyte-specific enhancer factor 2C
UniProt Comments for MEF2C
Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture ().
Research Articles on MEF2C
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Products associated with MEF2C recombinant protein
Pathways associated with MEF2C recombinant protein
Diseases associated with MEF2C recombinant protein
Organs/Tissues associated with MEF2C recombinant protein
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