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mstn recombinant protein :: Myostatin Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS537292 mstn recombinant protein
Unit / Price
0.01 mg  /  $310 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Myostatin (mstn), Recombinant Protein

 Also Known As   

Myostatin protein

 Product Synonym Names    GDF-8 protein
 Product Gene Name   

mstn recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    Region of Myostatin beta protein correspond ing to amino acids DFGLDCDEHS TESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGECEFV FLQKYPHTHL VHQANPRGSA GPCCTPTKMS PINMLYFNGK EQIIYGKIPA MVVDRCGCS.
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 Host    Human
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 Purity/Purification    > 98% pure
 Form/Format    Lyophilized with no additives. Reconstitute with water to 0.1 - 1.0 mg/ml. Due to the solubility reasons the protein should be kept at low pH.
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 Protein Type    Recombinant
 Biological Significance    Myostatin is a TGF beta family member that acts as an inhibitor of skeletal muscle growth. This muscle-specific cytokine interacts with Activin type I and type II receptors, and suppresses myoblast proliferation by arresting cell-cycle in the G1 phase. Suppression of myostatin activity facilitates muscle formation and may be useful in reducing and/or preventing adiposity and type-2 diabetes. Myostatin activity can be blocked by the Activin-binding protein Follistatin, and by the propeptide of Myostatin.
 Bioactivity    Determined by its ability to inhibit the proliferation of MPC-11 cells. The expected ED50 for this effect is 17.0-25.0 ng/ml.
 Endotoxin Levels    Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
 Contaminants    Supplied lyophilized with no additives.
 Expression System    E Coli
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 Preparation and Storage    Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of mstn recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for mstn recombinant protein

   Purified recombinant Human Myostatin protein
 Product Categories/Family for mstn recombinant protein    Cytokines & Growth Factors
 Applications Tested/Suitable for mstn recombinant protein   

User optimized

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NCBI/Uniprot data below describe general gene information for mstn. It may not necessarily be applicable to this product.
 NCBI GI #    319996677
 NCBI GeneID    100529165
 NCBI Accession #    NP_001188428.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001201499.1 [Other Products]
 Molecular Weight    25 kDa [Similar Products]
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 NCBI Official Full Name    growth/differentiation factor 8
 NCBI Official Symbol    mstn [Similar Products]
 NCBI Protein Information    growth/differentiation factor 8
 Protein Family    Growth/differentiation factor
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 Research Articles on mstn    1. Findings suggest that myostatin (MSTN) function is required for regulating the appropriate growth of skeletal muscle in medaka
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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