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Gns recombinant protein :: N-acetylglucosamine-6-sulfatase (Gns) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1361387 Gns recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $930 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,135 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,245 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,360 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,375 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,385 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,440 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,540 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,955 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,060 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,085 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,345 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,710 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

N-acetylglucosamine-6-sulfatase (Gns), Recombinant Protein

 Also Known As   

Recombinant Mouse N-acetylglucosamine-6-sulfatase (Gns)

 Product Gene Name   

Gns recombinant protein

[Similar Products]
 Product Synonym Gene Name    Gns [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    36-544aa, Full Length of Mature Protein
 Sequence    ARRPNVLLLL TDDQDAELGG MTPLKKTKAL IGEKGMTFSS AYVPSALCCP SRASILTGKY PHNHHVVNNT LEGNCSSKAW QKIQEPYTFP AILKSVCGYQ TFFAGKYLNE YGAPDAGGLE HIPLGWSYWY ALEKNSKYYN YTLSINGKAR KHGENYSVDY LTDVLANLSL DFLDYKSNSE PFFMMISTPA PHSPWTAAPQ YQKAFQNVIA PRNKNFNIHG TNKHWLIRQA KTPMTNSSIR FLDDAFRRRW QTLLSVDDLV EKLVKRLDST GELDNTYIFY TSDNGYHTGQ FSLPIDKRQL YEFDIKVPLL VRGPGIKPNQ TSKMLVSNID LGPTILDLAG YDLNKTQMDG MSLLPILKGD RNLTWRSDVL VEYQGEGRNV TDPTCPSLSP GVSQCFPDCV CEDAYNNTYA CVRTLSSLWN LQYCEFDDQE VFVEVYNITA DPDQITNIAK SIDPELLGKM NYRLMMLQSC SGPTCRTPGV FDPGYRFDLR LMFNSHGSVR TRRFSKHPL
 3D Structure    ModBase 3D Structure for Q8BFR4
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mouse
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Gns recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Gns recombinant protein

   The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
NCBI/Uniprot data below describe general gene information for Gns. It may not necessarily be applicable to this product.
 NCBI GI #    29789239
 NCBI GeneID    75612
 NCBI Accession #    NP_083640.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_029364.3 [Other Products]
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 UniProt Primary Accession #    Q8BFR4 [Other Products]
 UniProt Secondary Accession #    Q3TWT0; Q8BJJ7; Q8BK91 [Other Products]
 UniProt Related Accession #    Q8BFR4 [Other Products]
 Molecular Weight    61,175 Da
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 NCBI Official Full Name    N-acetylglucosamine-6-sulfatase
 NCBI Official Synonym Full Names    glucosamine (N-acetyl)-6-sulfatase
 NCBI Official Symbol    Gns [Similar Products]
 NCBI Official Synonym Symbols   
G6S; C87209; N28088; AU042285; 2610016K11Rik
[Similar Products]
 NCBI Protein Information    N-acetylglucosamine-6-sulfatase
 UniProt Protein Name    N-acetylglucosamine-6-sulfatase
 UniProt Synonym Protein Names   
Glucosamine-6-sulfatase; G6S
 Protein Family    Non-structural glycoprotein
 UniProt Gene Name    Gns [Similar Products]
 UniProt Synonym Gene Names    G6S [Similar Products]
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 Research Articles on Gns    1. Mice deficient in GNS showed lysosomal storage pathology and a phenotype that closely resembled human MPSIIID. Moreover, treatment of the GNS-deficient animals with GNS-encoding adeno-associated viral (AAV) vectors of serotype 9 delivered to the cerebrospinal fluid completely corrected pathological storage, improved lysosomal functionality in the CNS and somatic tissues, resolved neuroinflammation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Gns recombinant proteinDiseases associated with Gns recombinant protein
 Products by Pathway  Pathway Diagram
 Clathrin Derived Vesicle Budding Pathway antibodies  Clathrin Derived Vesicle Budding Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Glycogen Storage Diseases Pathway antibodies  Glycogen Storage Diseases Pathway Diagram
 Glycosaminoglycan Degradation Pathway antibodies  Glycosaminoglycan Degradation Pathway Diagram
 Glycosaminoglycan Degradation Pathway antibodies  Glycosaminoglycan Degradation Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 Heparan Sulfate Degradation Pathway antibodies  Heparan Sulfate Degradation Pathway Diagram
 Heparan Sulfate Degradation Pathway antibodies  Heparan Sulfate Degradation Pathway Diagram
 Keratan Sulfate Degradation Pathway antibodies  Keratan Sulfate Degradation Pathway Diagram
 Keratan Sulfate Degradation Pathway antibodies  Keratan Sulfate Degradation Pathway Diagram
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >19 publications with Gns and Kidney Diseases
 Nervous System Diseases Antibodies  >13 publications with Gns and Nervous System Diseases
 Death Antibodies  >10 publications with Gns and Death
 Proteinuria Antibodies  >8 publications with Gns and Proteinuria
 Brain Diseases Antibodies  >8 publications with Gns and Brain Diseases
 Central Nervous System Diseases Antibodies  >7 publications with Gns and Central Nervous System Diseases
 Hypertension Antibodies  >6 publications with Gns and Hypertension
 Inflammation Antibodies  >5 publications with Gns and Inflammation
 Fever Antibodies  >5 publications with Gns and Fever
 Mucopolysaccharidosis III Antibodies  >5 publications with Gns and Mucopolysaccharidosis III
Organs/Tissues associated with Gns recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >28 publications with Gns and Blood
 Kidney Antibodies  >15 publications with Gns and Kidney
 Brain Antibodies  >14 publications with Gns and Brain
 Muscle Antibodies  >7 publications with Gns and Muscle
 Liver Antibodies  >5 publications with Gns and Liver
 Heart Antibodies  >4 publications with Gns and Heart
 Lung Antibodies  >4 publications with Gns and Lung
 Eye Antibodies  >4 publications with Gns and Eye
 Bone Antibodies  >3 publications with Gns and Bone
 Skin Antibodies  >3 publications with Gns and Skin
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