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NDUFV2 recombinant protein :: NADH dehydrogenase [ubiquinone] flavoprotein 2 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS717229
SDS-PAGE
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.05 mg  /  $190 +1 FREE 8GB USB
0.1 mg  /  $285 +1 FREE 8GB USB
0.2 mg  /  $460 +1 FREE 8GB USB
0.5 mg  /  $750 +1 FREE 8GB USB
1 mg  /  $1,180 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NADH dehydrogenase [ubiquinone] flavoprotein 2 (NDUFV2), Recombinant Protein

 Also Known As   

Recombinant Human NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

 Product Synonym Names    NADH-ubiquinone oxidoreductase 24 kDa subunit
 Product Gene Name   

NDUFV2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    35-249aa; Partial
 Sequence    GGALFVHRDT PENNPDTPFD FTPENYKRIE AIVKNYPEGH KAAAVLPVLD LAQRQNGWLP ISAMNKVAEV LQVPPMRVYE VATFYTMYNR KPVGKYHIQV CTTTPCMLRN SDSILEAIQK KLGIKVGETT PDKLFTLIEV ECLGACVNAP MVQINDNYYE DLTAKDIEEI IDELKAGKIP KPGPRSGRFS CEPAGGLTSL TEPPKGPGFG VQAGL
 OMIM    600532
 3D Structure    ModBase 3D Structure for P19404
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 Host    E Coli
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of NDUFV2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for NDUFV2 recombinant protein

   Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
 Product Categories/Family for NDUFV2 recombinant protein    Transport
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 SDS-PAGE of NDUFV2 recombinant protein    NDUFV2 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for NDUFV2. It may not necessarily be applicable to this product.
 NCBI GI #    222080062
 NCBI GeneID    4729
 NCBI Accession #    NP_066552.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_021074.4 [Other Products]
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 UniProt Primary Accession #    P19404 [Other Products]
 UniProt Secondary Accession #    Q9BV41 [Other Products]
 UniProt Related Accession #    P19404 [Other Products]
 Molecular Weight    51kD
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 NCBI Official Full Name    NADH dehydrogenase
 NCBI Official Synonym Full Names    NADH:ubiquinone oxidoreductase core subunit V2
 NCBI Official Symbol    NDUFV2 [Similar Products]
 NCBI Official Synonym Symbols   
CI-24k
[Similar Products]
 NCBI Protein Information    NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
 UniProt Protein Name    NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
 UniProt Synonym Protein Names   
NADH-ubiquinone oxidoreductase 24 kDa subunit
 Protein Family    NADH dehydrogenase [ubiquinone] flavoprotein
 UniProt Gene Name    NDUFV2 [Similar Products]
 UniProt Entry Name    NDUV2_HUMAN
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 NCBI Summary for NDUFV2    The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19. [provided by RefSeq, Oct 2009]
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 UniProt Comments for NDUFV2    NDUFV2: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I 24 kDa subunit family.

Protein type: Energy Metabolism - oxidative phosphorylation; Mitochondrial; Oxidoreductase; EC 1.6.99.3; EC 1.6.5.3

Chromosomal Location of Human Ortholog: 18p11.22

Cellular Component: mitochondrial inner membrane; mitochondrial respiratory chain complex I; mitochondrion; myelin sheath

Molecular Function: 2 iron, 2 sulfur cluster binding; electron carrier activity; metal ion binding; NADH dehydrogenase (ubiquinone) activity

Biological Process: cardiac muscle development; cellular metabolic process; mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly; nervous system development

Disease: Mitochondrial Complex I Deficiency
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Product References and Citations for NDUFV2 recombinant protein

   Mitochondrial NADH-ubiquinone reductase complementary DNA sequences of import precursors of the bovine and human 24-kDa subunit.Pilkington S.J., Walker J.E.Biochemistry 28:3257-3264(1989) The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.Murray J., Zhang B., Taylor S.W., Oglesbee D., Fahy E., Marusich M.F., Ghosh S.S., Capaldi R.A.J. Biol. Chem. 278:13619-13622(2003) Initial characterization of the human central proteome.Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.BMC Syst. Biol. 5:17-17(2011) Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components.Ogura M., Yamaki J., Homma M.K., Homma Y.Biochem. J. 447:281-289(2012) An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.J. Proteomics 96:253-262(2014)
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 Research Articles on NDUFV2    1. The results show mitochondrial haplotypes associated with polymorphism of this gene are associated with elite middle and sprint power endurance in Japanese athletes
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NDUFV2 recombinant proteinPathways associated with NDUFV2 recombinant protein
 Reference Product  PubMed Publications
 NDUFV1 recombinant protein  >10 publications with NDUFV2 and NDUFV1
 NDUFS3 recombinant protein  >8 publications with NDUFV2 and NDUFS3
 NDUFS1 recombinant protein  >7 publications with NDUFV2 and NDUFS1
 NDUFS2 recombinant protein  >4 publications with NDUFV2 and NDUFS2
 NDUFS7 recombinant protein  >3 publications with NDUFV2 and NDUFS7
 NDUFA2 recombinant protein  >2 publications with NDUFV2 and NDUFA2
 NDUFS8 recombinant protein  >2 publications with NDUFV2 and NDUFS8
 NDUFAB1 recombinant protein  >1 publications with NDUFV2 and NDUFAB1
 Products by Pathway  Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Complex I Biogenesis Pathway antibodies  Complex I Biogenesis Pathway Diagram
 Electron Transport Chain Pathway antibodies  Electron Transport Chain Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 NADH Dehydrogenase (ubiquinone) Fe-S Protein/flavoprotein Complex, Mitochondria Pathway antibodies  NADH Dehydrogenase (ubiquinone) Fe-S Protein/flavoprotein Complex, Mitochondria Pathway Diagram
 NADH Dehydrogenase (ubiquinone) Fe-S Protein/flavoprotein Complex, Mitochondria Pathway antibodies  NADH Dehydrogenase (ubiquinone) Fe-S Protein/flavoprotein Complex, Mitochondria Pathway Diagram
Diseases associated with NDUFV2 recombinant proteinOrgans/Tissues associated with NDUFV2 recombinant protein
 Disease Name  Pubmed Publications
 Bipolar Disorder Antibodies  >20 publications with NDUFV2 and Bipolar Disorder
 Schizophrenia Antibodies  >16 publications with NDUFV2 and Schizophrenia
 Nervous System Diseases Antibodies  >11 publications with NDUFV2 and Nervous System Diseases
 Movement Disorders Antibodies  >4 publications with NDUFV2 and Movement Disorders
 Heart Diseases Antibodies  >2 publications with NDUFV2 and Heart Diseases
 Cardiovascular Diseases Antibodies  >2 publications with NDUFV2 and Cardiovascular Diseases
 Death Antibodies  >2 publications with NDUFV2 and Death
 Cardiomyopathies Antibodies  >2 publications with NDUFV2 and Cardiomyopathies
 Anxiety Disorders Antibodies  >1 publications with NDUFV2 and Anxiety Disorders
 Neurobehavioral Manifestations Antibodies  >1 publications with NDUFV2 and Neurobehavioral Manifestations
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >20 publications with NDUFV2 and Brain
 Blood Antibodies  >4 publications with NDUFV2 and Blood
 Muscle Antibodies  >4 publications with NDUFV2 and Muscle
 Nerve Antibodies  >2 publications with NDUFV2 and Nerve
 Eye Antibodies  >2 publications with NDUFV2 and Eye
 Adrenal Gland Antibodies  >1 publications with NDUFV2 and Adrenal Gland
 Liver Antibodies  >1 publications with NDUFV2 and Liver
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