P03903.1
[Other Products]
UniProt Primary Accession #
|
[Other Products]
NCBI Official Full Name
NADH-ubiquinone oxidoreductase chain 4L
UniProt Protein Name
NADH-ubiquinone oxidoreductase chain 4L
UniProt Synonym Protein Names
NADH dehydrogenase subunit 4L
UniProt Synonym Gene Names
UniProt Entry Name
NU4LM_MOUSE
UniProt Comments for Mtnd4l
MT-ND4L: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Defects in MT-ND4L are a cause of Leber hereditary optic neuropathy (LHON). LHON is a maternally inherited disease resulting in acute or subacute loss of central vision, due to optic nerve dysfunction. Cardiac conduction defects and neurological defects have also been described in some patients. LHON results from primary mitochondrial DNA mutations affecting the respiratory chain complexes. Belongs to the complex I subunit 4L family.
Protein type: EC 1.6.5.3; Energy Metabolism - oxidative phosphorylation; Oxidoreductase; Membrane protein, integral; Mitochondrial; Membrane protein, multi-pass
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with Mtnd4l recombinant protein
Pathways associated with Mtnd4l recombinant protein
|