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NCR2 recombinant protein

Scan QR to view Datasheet Catalog #    MBS205541
SDS-Page
Unit / Price
0.1 mg  /  $310 +1 FREE 8GB USB
0.5 mg  /  $720 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NCR2, Recombinant Protein

 Also Known As   

NCR2, 19-130aa, Human, His tag, E Coli (Denatured)

 Product Synonym Names    Natural cytotoxicity triggering receptor 2 isoform 1; CD336; LY95; NK-p44 NKP44
 Product Gene Name   

NCR2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHHHHH SSGLVPRGSH MSQAQSKAQV LQSVAGQTLT VRCQYPPTGS LYEKKGWCKE ASALVCIRLV TSSKPRTMAW TSRFTIWDDP DAGFFTVTMT DLREEDSGHY WCRIYRPSDN SVSKSVRFYL VVS
 OMIM    AJ225109 mRNA
 3D Structure    ModBase 3D Structure for O95944
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 Host    E Coli
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 Purity/Purification    > 80% by SDS-PAGE
 Form/Format    Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol, 0.4M urea
 Concentration    1.0 mg/ml (determined by Bradford assay) (lot specific)
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 Antigen Species    Human
 Tag Information    His-tag
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of NCR2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for NCR2 recombinant protein

   NCR2 belongs to the natural cytotoxicity receptor (NCR) family and contains 1 Ig-like (immunoglobulin-like) domain. This protein interacts with TYROBP/DAP12 and is selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d lymphoid cells. NCR2 is a cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Recombinant human NKP44 protein, fused to His-tag at N-terminus, was expressed in E Coli
 Product Categories/Family for NCR2 recombinant protein    Signal Transduction
 Applications Tested/Suitable for NCR2 recombinant protein   

SDS-PAGE

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 SDS-Page of NCR2 recombinant protein    NCR2 recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for NCR2. It may not necessarily be applicable to this product.
 NCBI GI #    153945782
 NCBI GeneID    9436
 NCBI Accession #    NP_004819.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004828.3 [Other Products]
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 UniProt Primary Accession #    O95944 [Other Products]
 UniProt Secondary Accession #    Q9H562; Q9H563; Q9H564; Q9UMT1; Q9UMT2 [Other Products]
 UniProt Related Accession #    O95944 [Other Products]
 Molecular Weight    15.0 kDa (133aa)
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 NCBI Official Full Name    natural cytotoxicity triggering receptor 2 isoform 1
 NCBI Official Synonym Full Names    natural cytotoxicity triggering receptor 2
 NCBI Official Symbol    NCR2 [Similar Products]
 NCBI Official Synonym Symbols   
LY95; CD336; NKP44; NK-p44; dJ149M18.1
[Similar Products]
 NCBI Protein Information    natural cytotoxicity triggering receptor 2
 UniProt Protein Name    Natural cytotoxicity triggering receptor 2
 UniProt Synonym Protein Names   
Lymphocyte antigen 95 homolog; NK cell-activating receptor; Natural killer cell p44-related protein; NK-p44; NKp44; CD_antigen: CD336
 Protein Family    Natural cytotoxicity triggering receptor
 UniProt Gene Name    NCR2 [Similar Products]
 UniProt Synonym Gene Names    LY95; NK-p44; NKp44 [Similar Products]
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 UniProt Comments for NCR2    Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
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Product References and Citations for NCR2 recombinant protein

   Vitale M, Bottino C et al. (1998) J Exp Med. 15;187 (12):2065-72.
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 Research Articles on NCR2    1. On CD56(+) CD3(-) cells, NKp44 and NKp46 expressions were high in the acute hepatitis E patients, whereas NKp30, NKp44, NKp46 and NKG2D were high in the recovered individuals.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NCR2 recombinant proteinPathways associated with NCR2 recombinant protein
 Reference Product  PubMed Publications
 NCR1 recombinant protein  >65 publications with NCR2 and NCR1
 NCR3 recombinant protein  >47 publications with NCR2 and NCR3
 IL15 recombinant protein  >7 publications with NCR2 and IL15
 KLRD1 recombinant protein  >6 publications with NCR2 and KLRD1
 TYROBP recombinant protein  >6 publications with NCR2 and TYROBP
 NCAM1 recombinant protein  >4 publications with NCR2 and NCAM1
 KIR2DL1 recombinant protein  >3 publications with NCR2 and KIR2DL1
 CD226 recombinant protein  >3 publications with NCR2 and CD226
 IL2 recombinant protein  >2 publications with NCR2 and IL2
 KLRC1 recombinant protein  >2 publications with NCR2 and KLRC1
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies  Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Natural Killer Cell Mediated Cytotoxicity Pathway antibodies  Natural Killer Cell Mediated Cytotoxicity Pathway Diagram
 Natural Killer Cell Mediated Cytotoxicity Pathway antibodies  Natural Killer Cell Mediated Cytotoxicity Pathway Diagram
Diseases associated with NCR2 recombinant proteinOrgans/Tissues associated with NCR2 recombinant protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >14 publications with NCR2 and Inflammation
 Necrosis Antibodies  >11 publications with NCR2 and Necrosis
 Liver Diseases Antibodies  >7 publications with NCR2 and Liver Diseases
 Lupus Erythematosus, Systemic Antibodies  >2 publications with NCR2 and Lupus Erythematosus, Systemic
 Disease Models, Animal Antibodies  >2 publications with NCR2 and Disease Models, Animal
 Kidney Diseases Antibodies  >2 publications with NCR2 and Kidney Diseases
 Demyelinating Diseases Antibodies  >2 publications with NCR2 and Demyelinating Diseases
 Liver Cirrhosis, Experimental Antibodies  >1 publications with NCR2 and Liver Cirrhosis, Experimental
 Eye Diseases Antibodies  >1 publications with NCR2 and Eye Diseases
 Organ/Tissue Name  Pubmed Publications
 Bone Marrow Antibodies  >4 publications with NCR2 and Bone Marrow
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